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Biomedical subjects

F Cauwe

Publications and source records attributed to F Cauwe.

5 recordsLinked to original sources

Technetium-99m HM-PAO single photon emission computed tomography imaging in transient global amnesia.

Five right-handed patients with pure transient global amnesia were evaluated with technetium-99m hexamethylpropyleneamine oxime single photon emission computed tomography after the amnesic attack. Independent of the interval between the procedure and the amnesic episode, single photon emission computed tomography demonstrated a decreased cerebral blood flow in the left temporal lobe in one patient and in the left parietotemporal region in three patients, with a more marked reduction in the temporal lobe. The remaining three patients were normal. A control single photon emission computed tomographic study was carried out in one patient 3 months after the amnesic attack and showed a left-sided persistent temporal hypoperfusion. These findings suggest that in some patients, transient global amnesia can be due to a vascular mechanism requiring strong investigations for vascular risk factors and appropriate treatment. During a follow-up period of 12 to 32 months, none of the patients with regional hypoperfusion suffered cerebrovascular events, suggesting that single photon emission computed tomography has no predictive value for further stroke.

Aged

Quantitative organ-uptake measurement with a gamma camera.

A study was carried out to investigate the use of a gamma camera for quantitative measurement of the absolute radioactivity in internal organs. Phantoms simulating different patient conditions were used to derive the attenuation correction factor and the conversion factor which relates a known radioactive dose to organ activity. The delimitation of the source image was established by means of an isocontour of maximum count rate. A mathematical approach was used for achievement of isosensitivity with depth of the organ and for correction for background. The accuracy of the procedure was proven by the recovery over the stomach area of the ingested activity. The method is applied to the quantitative assessment of the splenic red-cell volume.

Erythrocytes

The long-term results of the treatment with transtympanic ventilation tubes in children with chronic secretory otitis media.

In the present report we discuss the short-term and long-term results of treatment with transtympanic ventilation tubes in 140 children with chronic secretory otitis media. Important findings are: after 6 months only 40% and after 12 months only 5% of the inserted grommets are still draining. A good clinical result is obtained in 72% after 6 months, and in 52% after 12 months. With a long follow-up, up to 10 years, 71% of the children suffering from chronic secretory otitis media and treated with grommets, can be considered as cured, with or without a small complication. The poorest results are obtained after a follow-up of 2-3 years. Children under 7 years have a better prognosis than older children. There is also a better prognosis in children with serous effusions than in those with a glue ear. We noticed very few complications in our treatment with grommets: no sensorineural hearing loss and a persisting perforation in 2% of the treated ears.

Adolescent

Proximal femur density in type 1 and 2 diabetic patients.

This study reports on the proximal femur mineral content in 36 Type 1 and 60 Type 2 diabetic patients. Bone mass measurements were performed in the neck, Ward's triangle and in the trochanteric area of the femur, using dual-photon absorptiometry with 153Gd. Bone mineral density (BMD) was significantly decreased in Type 1 diabetic men and women as well in Type 2 men, when compared with a non diabetic matched population. In Type 1 men, neck and Ward's triangle densities were reduced from 0.94 +/- 0.05 to 0.86 +/- 0.11 (p = 0.007) and from 0.87 +/- 0.10 to 0.74 +/- 0.14 g.cm-2 (p = 0.011), respectively. In Type 1 women, BMD was reduced from 0.97 +/- 0.10 to 0.90 +/- 0.10 g.cm-2 (p = 0.023) in the femoral neck. In Type 2 men, BMD in Ward's triangle was also significantly lower than in controls: 0.69 +/- 0.14 vs 0.76 +/- 0.19 g.cm-2, respectively (p = 0.001). In contrast, no bone loss was observed in a group of Type 2 overweight diabetic women. No statistical correlation was observed between bone loss and age, duration of diabetes, body mass index, C-peptide levels, daily insulin doses, HbA1 and the presence of diabetic complications. In conclusion, long-standing Type 1 diabetic men and women and Type 2 diabetic men have a decrease in the proximal femur bone mass. Type 2 diabetic women appear to be protected from diabetic osteopenia.

Adult