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Biomedical subjects

F Casper

Publications and source records attributed to F Casper.

26 records · Page 2Linked to original sources
PubMed1986

[Thrombocytopenia following intracervical prostaglandin priming].

Thrombocyte aggregation with normochromic anaemia occurred in a gravida III of 27 years of age with sonographically confirmed foetal hydrocephalus, after prostaglandin E2 cervical priming. The authors discuss the differential diagnostic possibilities, but the actual genesis of the changes remains unclear. Hence, it is recommended to check with particular care especially in induction of abortion, the coagulation system with the thrombocytes, over and above the well-known prostaglandin side effects. Special attention must be paid to the occurrence of allergic reactions, and it must always be borne in mind that induction of abortion after the 14th week of gestation is a risky matter (1).

Abortion, Induced↗
PubMed1986

[Are small urodynamic evaluation units competitive?].

Urodynamic investigation allows a classification and differential diagnosis of disorders of the lower urinary tract. The number of parameters registered is fixed by patient selection and then economical feasibility of the urodynamic unit. Differentiating stress urinary incontinence and urge incontinence or neurogenic disorders, which is of clinical importance, small two-channel recorders showed to be a competitive screening-method.

Adolescent↗
PubMed1985

[Ureteral endometriosis].

In the literature, figures quoted for the involvement of the urinary tract range between 1% and 11%, adenomyosis being the exception rather than the rule. The problems of preoperative diagnosis are illustrated with reference to five of the author's cases. In four-fifths of the cases definitive confirmation of the findings was only obtained by intraoperative examination with a rapid incision. In cases with preserved renal function, ureteroneocystostomy employing the psoas hitch technique with subsequent hormone treatment was the treatment of choice. Summarizing, endometriosis should be considered in differential diagnosis in premenopausal women with unclear complaints and micturition disorders in the distal one-third of the ureter.

Diagnosis, Differential↗
PubMed1985

[Value of flowmetry in disorders of bladder emptying].

After definition of the 'rate of increase in urinary flow' uroflowmetry still does not seem to be of any value for the differentiation of abnormalities of micturition in women as a screening method. Correlating several parameters of uroflowmetry with different subjective and objective data and the final urodynamic diagnosis in 1113 sophisticated urodynamic studies we did not find a discriminatory value of any of the parameters described.

Adult↗
PubMed1982

[Palliative urinary diversion in cases of cancer of the pelvis].

The introduction of percutaneous nephrostomy under xc-ray control or ultra-sonic control makes it possible to do the operation even in patients with a bad general condition. The decision for palliative urinary diversion in cases of cancer of the pelvis is therefore largely an ethical question. A group of patients with palliative urinary diversion (n = 48) was compared to a group with iatrogenic obstruction of the urinary tracts but without recurrence of carcinoma (n = 26). Six months later only 23 of the 48 Patients in the palliative group were alive, whereas 23 of the 26 patients without recurrence of cancer were alive. After 24 months, 35 of the 48 patients with incurable cancer had died. The indications are listed.

Adult↗
PubMedDate not supplied

[Significance of pathological alpha-1-fetoprotein levels in the framework of prenatal diagnosis].

Merkatz (1984) showed that in 68% of live birth with Down Syndrome maternal age was 34 years or less. It would be desirable to define a high risk collective of women younger then 35 years with the help of a screening test, which could further on lead to a prenatal diagnostics. Several studies showed that low maternal serum alpha-fetoprotein levels (SAFP) in pregnancy is associated with fetal chromosomal abnormalities. The results of a retrospective study at the Department of Obstetrics and Gynecology at University of Mainz showed that maternal SAFP-level does not accomplish the demand of a prenatal screening test, because only 17% of the Down Syndrome could be diagnosed by this parameter. In case of trisomy 13 and 18 SAFP-concentrations were normal or even increased, maybe on account of the combination with other malformations like neural-tube or abdominal-wall defects.

Adult↗
PubMedDate not supplied

[Pre- and postpartum hemostatic characteristics in pregnancy-related hypertension and pre-eclampsia in comparison with normotensive pregnancies].

Pregnancy is accompanied by a physiological activation of intravascular coagulation; however without disorder. Normal markers of coagulation are unchanged despite activation. Special coagulation parameter--such as Thrombin-Antithrombin-III-complex (TAT) or D-Dimer are increased also in normal pregnant women. Pregnancy induced hypertension (SIH) and preeklampsia may be associated with a disorder of coagulation that precedes the well known clinical manifestation of hypertension. Therefore it was the aim of the study to distinguish both the pregnancy induced hypertension (15 patients) and preeklampsia (10 patients) as far as it is possible by coagulation parameters such as thrombin generation (by TAT), fibrinolysis (by D-Dimer), AT-III, platelets and others comparing them with 25 normotensive pregnancies. In preeklampsia, the results showed that clinical signs were associated with simultaneous coagulation abnormalities. TAT and D-Dimere are significant increased whereas a decrease of AT-III and platelets was observed. There are no significant differences between SIH and normal pregnancies. Three days after delivery there was an increase of D-Dimer, AT-III and platelets and a decrease of TAT-complex in all groups. For risk pregnancy, the parameters TAT and D-Dimer may be useful as screening test. They although may support confirming the diagnosis of preeklampsia.

Adult↗