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Biomedical subjects

F Carsuzaa

Publications and source records attributed to F Carsuzaa.

At least 37 records · Page 2Linked to original sources

[Blue nevus of the scalp associated with a meningeal melanocytoma].

INTRODUCTION: Headache opposite to a blue nevus of the scalp can reveal intra cranial melanotic lesions. CASE REPORT: A 25-year-old man caucasian was admitted to hospital for a first generalized tonic-clonic seizure. For six months, he has had episodic frontal-temporal right headache opposite to a blue pigmentary cutaneous congenital lesion in frontal territory (histology confirmed benign blue nevus). Neurologic examination noted a right congenital hereditary ophtalmoplegia. Cerebral MRI showed a right rolandic tumor with diffuse leptomeninge infiltration. This patient was operated of a meningeal melanocytoma with leptomeninges melanosis. DISCUSSION: The apparition of headache related to a blue nevus must lead to realize a cerebral MRI to look for a neuroectodermic hamartoma: melanotic tumor (in particular melanoma), or leptomeninges melanosis with high potential of degeneration. Meningeal melanocytoma is a rare benign spinal or intra cranial melanotic tumor.

Adult↗

[Cutaneous metastatic Crohn disease. Apropos of a case].

The authors report the case of a 54-year old man suffering from facial papulonodular eruption. He has Crohn's disease which was diagnosed 36 years ago. There were no clinical symptoms of the disease when the cutaneous manifestations occurred. The biopsy of a cutaneous lesion showed cutaneous granuloma at skin's level. Having no other etiology, we shall diagnose it as a cutaneous metastatic Crohn's disease. Derived sulfasalazine (Pentasa) healed all lesions in 1 month. This observation reminded us to that it is essential to biopsy all atypical cutaneous lesions occurring in a Crohn's disease case.

Crohn Disease↗

[Mycosis fungoides].

Explore the source record for details and available documents.

Antineoplastic Agents↗

[Sweet's syndrome and aseptic abscess of the spleen].

Extra-cutaneous manifestations of neutrophilic dermatosis are exceptional and diverse: they consist of inflammatory infiltrates with neutrophil polymorphonuclears, without evidence of infectious agents. Localisations to the lung are the most frequently observed. A single observation of spleen involvement has been reported in a case of Sneddon-Wilkinson's disease. Herein we report the case of an aseptic splenic abscess during the course of a Sweet's syndrome.

Abscess↗

[Panniculitis-fasciitis syndrome disclosing systemic erythematous lupus].

INTRODUCTION: Panniculitis is a common manifestation of lupus, but is rarely the first manifestation in systemic lupus erythematosus. We report a case associated with fasciitis. CASE REPORT: A 67-year-old man was hospitalized for fever, pleuropericarditis, subcutaneous diffuse infiltration of the two thighs and the abdomen due to panniculitis and lupic fasciitis. Antiphospholipid antibody test was positive. There was non antiphospholipid syndrome. COMMENTS: Panniculitis can occur simultaneously or a few months or years before systemic lupus erythematosus. An association with fasciitis should be entertained whenever the cutaneous involvement is extensive and firm. In such a situation, deep biopsies are indicated. Observations of further cases will help identify the role of general steroid therapy in fasciitis-panniculitis and systemic lupus erythematosus.

Aged↗

[Capillary leak syndrome disclosing Ofuji's papuloerythroderma].

INTRODUCTION: Capillary leak syndrome is a specific entity among syndromes with capillary hyperpermeability. Endothelial cell activation is related to the higt level of adhesion molecules (sICAM-1, sVCAM-&, sCD62E) possibly due to several cytokines (IL-2, TNF ...). CASE REPORT: An 84-year-old woman was hospitalized for erythroderma. Ofujui papuloerythroderma was diagnosed and edema was attributed to capillary leak. A kinetic study of several cytokines and adhesion molecules sCD62E, sVCAM-1 and sICAM-1 was done. Outcome was favorable with corticopuvatherapy. DISCUSSION: The capillary leak syndrome reported here is simlar to that described in other erythrodermas with or without lymphoma. The keratinocyte would be activated by the CD4 T lymphocyte via the gamma-interferon mediator. The T cell secretes cytokines (interleukin-1, tumor necrosis factor ...) which activates the endothelium and increases vascular permeability. The level of adhesion molecules and changes observed during the episode of edema demonstrated the endothelial activation.

Aged↗

Cutaneous findings in hairy cell leukemia. Review of 84 cases.

The authors of this paper present a retrospective analysis of 84 cases of hairy cell leukaemia diagnosed over the past ten years in two haematology departments. Cutaneous manifestations are noted on 47 occasions, 58% of infectious origin with 60% of these infections due to bacterial agents, results which are in relatively close accord with those of the Mayo Clinic. Since no cases of necrotic angeitis or neutrophilic dermatosis are reported, the considerable number of publications concerning these affections give a poor indication of their rarity. Prospective studies will be required to evaluate the incidence of spinocellular carcinoma and melanoma, while specific lesions are only infrequently encountered and do not appear to bear the same unfavourable prognosis as in other haemopathia.

Humans↗

[Patch-like sweat gland necrosis in AIDS].

Hard plaques located in pressure areas were observed in an HIV-infected male patient at the AIDS stage. Histological examination of the skin showed necrosis of the eccrine sweat glands. The relationship between this disease and eccrine neutrophilic hidradenitis observed in HIV infection is discussed. The authors propose a concept of eccrine sweat gland lesion spectrum.

Acquired Immunodeficiency Syndrome↗