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Biomedical subjects

F Caravati

Publications and source records attributed to F Caravati.

7 recordsLinked to original sources

[Cardiac rhythm disturbances in hypertensive cardiopathy].

Patients with hypertensive heart disease are at a significantly increased risk for cardiovascular morbidity and mortality. Ultrastructural and gross anatomical cardiac changes, combined with hemodynamic and neurovegetative balance fluctuations, are frequently responsible for cardiac arrhythmias of atrial and/or ventricular origin. The prevalence, the pathophysiologic mechanism and the prognostic significance of cardiac rhythm disturbances occurring in hypertensive heart disease are discussed in this review.

Arrhythmias, Cardiac↗

Effects of surgical trauma of laparoscopic vs. open cholecystectomy.

The effects of surgical trauma resulting from laparoscopic cholecystectomy and open cholecystectomy, were compared by assessing the postoperative acute phase alterations of selected plasma proteins, hormones and lymphocyte subpopulations in fifty-seven patients prior to elective cholecystectomy. Patients were prospectively randomized to undergo either laparoscopic cholecystectomy (n = 30) or open cholecystectomy (n = 27). Duration of operation and general anesthesia was similar in the two patient groups. The laparoscopic cholecystectomy patients had a shorter postoperative stay in hospital (3.1 (0.5) days vs. 7.1 (1.6) days; p < 0.001). In open cholecystectomy patients a significantly greater postoperative acute phase increase in plasma C-reactive protein (p < 0.001), cortisol (p < 0.05), and prolactin blood level (p < 0.001) was recorded. The postoperative acute phase decrease in the blood total-T-lymphocyte count (CD3 cells) and in the activated-lymphocyte count (OKDR cells) was significantly greater after open cholecystectomy (p < 0.05). These results, showing that acute phase responses are less marked after laparoscopic cholecystectomy than after open cholecystectomy, support the concept that the laparoscopic procedure is less traumatic.

Acute-Phase Reaction↗

[Incidence and treatment of local recurrences after conservative surgical treatment for cancer of the breast].

Long-term survival is comparable after total mastectomy or conservative surgery for early breast cancer. Our purpose was to evaluate the rate and therapy of breast relapse at the Regional Hospital of Varese (Italy) in a 10 years period. From 1/1/1980 to 31/12/1990 a total of 606 patients with early breast cancer (Stage I or II early) were evaluated. They all were submitted to quadrantectomy, axillary dissection and radiotherapy. In case of metastases to the axillary lymph nodes, hormono or chiotherapy were performed. 425 patients were regularly followed for a period of 2.5-13 years. In 15 patients (3.2%) a local recurrence was discovered. They were treated as follows, 8 patients: mastectomy, 4 patients: conservative surgery, 4 patients: no therapy. The surgical approach of the local recurrence, mastectomy or conservative surgery, does not influence long-term survival of patients treated with conservative surgery and radiotherapy for early stage breast cancer. Conservative surgery is often possible in treating local recurrence without interfering with complete removal of the tumor and long-term survival.

Antineoplastic Combined Chemotherapy Protocols↗

[Acute postintervention cholecystitis].

A case of postoperative cholecystitis in a 64 years old man is reported. This is a nosological entity characterized by gallbladder distension without any patent obstacle in the cystic duct and constancy of necrosis involving all the parietal layers. Clinical signs and symptoms are aspecific. Mortality rate is high and diagnosis has to be done quickly because the gallbladder necrosis makes cholecystectomy compulsory on such patients.

Acute Disease↗