[Case no 1. Neuroepithelial dysembryoplastic tumor].
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Biomedical subjects
Publications and source records attributed to F Brami-Zylberberg.
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THE TECHNIQUE: Today, magnetic resonance imaging (MRI) is the exploration of choice for a number of central nervous system disorders. This technique, which does not use ionising rays, examines the encephalus in all its dimensions. Various sequences are used to study the cerebral parenchyma: specific sequences in T1, with or without injection of a contrast product, specific sequence in T2, and FLAIR sequence. THE RESULTS OBTAINED: The diffusion and perfusion imaging respectively reveal the movement of the water molecules and the cerebral microcirculation. Visualisation of the arteries and veins is non-invasive with magnetic resonance angiographical techniques. Study of the chemical composition of tissues (magnetic resonance spectroscopy) and of cerebral activation (functional activation imaging) will not be addressed.
THE MRI DIAGNOSTIC SUPPORT: Magnetic resonance imaging is an efficient technique for revealing an intercranial tumor, and specifying its topography and loco-regional impact. A macroscopical approach is possible with MRI, since it distinguishes the components: tumoral tissue, cyst, necrosis and hemorrhage. DEPENDING ON THE TUMOR: Assessment of the tumoral limits is easy for extra-axial tumors. However, it is imprecise or even impossible for infiltrating intra-axial tumors. MRI specificity is low, however some lesions such as meningiomas, glioblastomas, arachnoid cysts and neurinomas are evocative.
IN ARTERIAL ISCHEMIC PATHOLOGY: Magnetic resonance imaging is increasingly proposed for any suspicion of cerebral vascular accident. Because of its diffusion sequences, it permits the rapid diagnosis and screening of ischemic lesions and provides prognostic information. FOR OTHER CEREBRAL VASCULAR DISORDERS: Intra-parenchymatous and sub-arachnoid hemorrhages are easily revealed by MRI. Today, MRI is the most effective examination for the diagnosis of venous thrombosis and of its impact on the parenchyma.
CRANIO-ENCEPHALIC TRAUMAS: Scanography remains the examination of choice. However, MRI can be useful in diagnosis of diffuse axional lesions, not clearly visualized with scanography, and for screening the subsequent lesions. INFECTIOUS OR INFLAMMATORY LESIONS: Some are very evocative with MRI: cerebral abscesses, notably herpetic encephalitis and Creutzfeldt-Jacob's disease. If multiple sclerosis is suspected, MRI is considered as the principle para-clinical examination able to confirm the diagnosis with the first episode. It also supplies data for the diagnosis of metabolic, toxic and degenerative diseases.