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F Bouvet

Publications and source records attributed to F Bouvet.

13 recordsLinked to original sources

[Anaesthetic-induced myocardial preconditioning: fundamental basis and clinical implications].

OBJECTIVE: Volatile halogenated anaesthetics offer a myocardial protection when they are administrated before a myocardial ischaemia. Cellular mechanisms involved in anaesthetic preconditioning are now better understood. The objectives of this review are to understand the anaesthetic-induced preconditioning underlying mechanisms and to know the clinical implications. DATA SOURCES: References were obtained from PubMed data bank (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) using the following keywords: volatile anaesthetic, isoflurane, halothane, sevoflurane, desflurane, preconditioning, protection, myocardium. DATA SYNTHESIS: Ischaemic preconditioning (PC) is a myocardial endogenous protection against ischaemia. It has been described as one or several short ischaemia before a sustained ischemia. These short ischaemia trigger a protective signal against this longer ischaemia. An ischemic organ is able to precondition a remote organ. It is possible to replace the short ischaemia by a preadministration of halogenated volatile anaesthetic with the same protective effect, this is called anaesthetic PC (APC). APC and ischaemic PC share similar underlying biochemical mechanisms including protein kinase C, tyrosine kinase activation and mitochondrial and sarcolemnal K(ATP) channels opening. All halogenated anaesthetics can produce an anaesthetic PC effect. Myocardial protection during reperfusion, after the long ischaemia, has been shown by successive short ischaemia or volatile anaesthetic administration, this is called postconditioning. Ischaemic PC has been described in humans in 1993. Clinical studies in human cardiac surgery have shown the possibility of anaesthetic PC with volatile anaesthetics. These studies have shown a decrease of postoperative troponin in patient receiving halogenated anaesthetics.

Anesthetics, Inhalation↗

Randomised trial of preventive nasal ventilation in Duchenne muscular dystrophy. French Multicentre Cooperative Group on Home Mechanical Ventilation Assistance in Duchenne de Boulogne Muscular Dystrophy.

Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy in children. Paralysis of respiratory muscles causes a decrease in forced vital capacity (FVC) from age 12 years, and death occurs between 20 and 25 years old and is usually related to respiratory insufficiency. Uncontrolled studies suggest that early home use of nasal intermittent positive-pressure ventilation (NIPPV) in DMD patients free of respiratory failure could limit progression of the restrictive syndrome and therefore improve survival because efficacy of preventive NIPPV has not been demonstrated in a controlled trial, we undertook a randomised multicentre study in which 70 patients with DMD were included. Patients were free of daytime respiratory failure and FVC was between 20 and 50% of predicted values. At least 6 h of nocturnal NIPPV (n = 35) was compared with conventional treatment (n = 35). During a mean follow-up of 52 months, 10 patients died, 8 in the NIPPV group and 2 in the control group (p = 0.05, log-rank test). No differences were observed between the two groups for occurrence of hypercapnia, decrease of FVC below 20% of initial values, or use of necessary mechanical ventilation. Preventive NIPPV did not improve respiratory handicap and reduced survival of DMD patients. Use of NIPPV for preventive purposes should be avoided in patients with FVC between 20 and 50% of predicted values.

Adolescent↗

[Management of neuromuscular training and psychotherapy].

In 9 out of 10 cases it is a very simple matter to persuade children age 7 to 9 years to stop sucking their thumbs by means of very elementary and brief supportive psychotherapy. In the majority of cases it is possible, three months after interruption of the habit and after studying the morphologic improvement, to decide whether treatment should be completed by education of deglutition and of phonetic articulation, possible after previous mechanical treatment if this is justified by the residual vestibulolingual bite disorder.

Child↗

[An index for induction of labour. A scheme based on Parzen's method (author's transl)].

It would seem to be necessary to make a score for pre-induction which would give the highest success rate and which would be available to all members of the obstetrical team, since there has been such a constant increase in the number of indications for induction of labour. Following a study based on 255 inductions the authors have been able to work out a system for calculating the prognosis according to the different classical scores used up till now and they have, after treating the information available, been able to work out a score according to the analytical method of Parzen which allows discrimination. In 95 per cent of cases one can predict the successful outcome by considering just 6 parameters: consistency of the cervix, the height of the presenting part, the length of the cervix, the height of the uterine fundus, and an estimation of the fetal weight and the state of the membranes. A complete list of the group that failed is furnished by the computer which could coordinate each new case in two minutes. As the study concerned itself with only 18 variables, a new study should be carried out on 1,000 case histories which would include some extra parameters such as: tocolytics used in pregnancy, cerclage (Shirodkar's stitch), the psychological state of the mother...which might shift the relative importance of the six variable that have been kept on perhaps even show how a percentage could be worked out of the cases classified using a smaller number of parameters to be taken into account.

Birth Weight↗

[Puerperium].

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Female↗

[Our operative strategy in the cure of genital prolapse by high approach].

The work from the School of Broca has made it possible to specify simple techniques which at one and the same time deal with genital prolapse and stress incontinence. These results, which for a long time had been disappointing, seem now to have improved in the last few years. The authors describe a triple operation which is particularly indicated in cases of large cystoceles found in patients suffering from the clinical condition of prolapse.

Female↗