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Biomedical subjects

F Boer

Publications and source records attributed to F Boer.

25 records · Page 2Linked to original sources
PubMed1994

The factor structure of the Buss and Plomin EAS Temperament Survey (parental ratings) in a Dutch sample of elementary school children.

The psychometric properties of the Buss and Plomin (1984) EAS Temperament Survey for Children (Parental Ratings) were examined in a sample of Dutch children between 4 and 13 years of age. Ratings were obtained from 230 mothers and 172 fathers. The findings presented here provide the lacking cross-validation of the original analyses by Rowe and Plomin (1977): Emotionality, activity, and shyness were independent temperaments, regardless of age and gender. The factorial position of the yet experimental Sociability scale is more ambiguous: Sociability was significantly related to both shyness and activity but was more strongly associated with shyness in the youngest age cohort and most strongly with activity in the oldest cohort. This age trend, combined with a positive association with activity, supports the premise that sociability cannot be equated to nonshyness and justifies the inclusion of a separate Sociability scale in the EAS. All four EAS scales are reliable in terms of internal consistency and interrater agreement, but one modification of the Sociability scale is needed.

Adolescent↗
PubMed1992

Uptake of sufentanil, alfentanil and morphine in the lungs of patients about to undergo coronary artery surgery.

We have studied the pulmonary extraction and retention of sufentanil, alfentanil and morphine using a double indicator technique in 30 patients undergoing elective aortocoronary bypass surgery. Patients were allocated to three groups (10 each) to receive sufentanil 43 micrograms, alfentanil 672 micrograms or morphine 1887 micrograms, mixed with indocyanine green as indicator. After sufentanil, mean peak extraction was 93.7% (95% confidence interval 87.1-100.4%) and release occurred after 16.1 (13.8-18.4) s; first-pass retention was 61.1 (51.3-70.9)%. After alfentanil, peak extraction was 67.4 (42.7-92.0)% and release occurred after 9.9 (8.5-11.3) s; first-pass retention was 10.1 (3.5-16.7)%. After morphine, peak extraction was 58.3 (44.4-72.2)% and release occurred after 7.2 (4.4-10.1) s; first-pass retention was 7.1 (-4.7-19.9)%. Both peak extraction and first-pass retention were significantly greater after sufentanil. There was no significant difference in the peak extraction and first-pass retention between alfentanil and morphine.

Alfentanil↗
PubMed1991

Siblings in foster care: success and failure.

This article reports on a retrospective study of 59 joint placements of siblings in foster homes, involving a total of 137 children. An overall picture is presented of the agencies' considerations in making these placements. The number of prematurely terminated placements in this group amounted to 14 (23.7%). Several factors that appear related to premature termination are discussed.

Adolescent↗
PubMed1991

Effect of thiopentone, etomidate and propofol on systemic vascular resistance during cardiopulmonary bypass.

We have studied the effect of thiopentone, etomidate and propofol on systemic vascular resistance (SVR) during cardiopulmonary bypass with constant pump flow in 30 patients undergoing elective coronary artery bypass surgery. SVR decreased to 78% of control values after thiopentone 4 mg kg-1, to 72% of control after etomidate 0.3 mg kg-1, and to 68% of control after propofol 2 mg kg-1; it returned to control values 10 min after administration of thiopentone and propofol and 7 min after administration of etomidate. Analysis of variance showed that there were no significant differences in the changes in SVR between the groups.

Adult↗
PubMed1990

Effect of propofol on peripheral vascular resistance during cardiopulmonary bypass.

Twenty-eight patients undergoing elective coronary artery bypass surgery were allocated randomly to receive either propofol 2 mg kg-1 or an equivalent volume of its vehicle during cardiopulmonary bypass with constant pump flow. Peripheral vascular resistance (PVR) was calculated from perfusion pressure and pump flow. After propofol, PVR decreased from 1767 (SD 415) dyn s cm-5 to a minimum of 1263 (283) dyn s cm-5 at 2 min, and remained significantly less than the control value until 12.5 min after administration of propofol. In the group given the vehicle, PVR did not change significantly. In a second study in 10 patients, venous blood samples were withdrawn before and 2, 4, 6, 8, 10, 20 and 30 min after injection of propofol 2 mg kg-1 during cardiopulmonary bypass, for measurement of blood concentrations of propofol. Concentrations were greater than predicted by a computer simulation based on published pharmacokinetic data. The decrease in PVR may be an important factor in the hypotension caused by propofol during induction of anaesthesia.

Aged↗
PubMed1989

[The Kleine-Levin syndrome].

Two boys, aged 12 and 13 years, showed relapsing periods of somnolence and excessive eating, starting after a viral illness. One of them also showed periodic disturbance of sexual impulse control. The symptomatic periods were followed by symptom-free intervals in a highly characteristic pattern. This gave the clue to the diagnosis Kleine-Levin syndrome. The cause of this syndrome is unknown, in some cases a relationship between infectious disease or traumatic brain damage has been postulated. A dysfunction of the hypothalamus and associated structures is suspected. The syndrome has a rather favourable prognosis. The symptoms can be relieved by amphetamines, methylphenidate and probably also by lithium carbonate.

Adolescent↗