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Biomedical subjects

F Bienvenu

Publications and source records attributed to F Bienvenu.

27 records · Page 2Linked to original sources
PubMed1981

[Plasmatic and urinary zinc in rheumatoid arthritis (author's transl)].

The analysis of the plasmatic and urinary levels of zinc in 50 patients presenting a non inflammatory disease and in 50 rheumatoid arthritis, points out to an high significative difference between plasmatic data (13,37 +/- 2,72 mumol/l and 11,32 +/- 2,22 mumol/l respectively ; p less than 0,001). No difference was found in urinary levels and neither age, nor sex, duration of the disease, most biologic parameters, nor long term medications can explain the difference which seems related to the inflammatory tissue process.

Adult↗
PubMed1981

Laser nephelometry of orosomucoid in serum of newborns: reference intervals and relation to bacterial infections.

Orosomucoid was evaluated by laser-nephelometry in 1790 sera collected from 1170 newborns. Within-run precision (CV) was 2.1 to 4.2%, between-run 2.9 to 5.2%. Results correlated well with radial immunodiffusion (r = 0.989). Results can be obtained within 1 h. Orosomucoid concentrations in serum at birth range from 130 to 200 mg/L and are influenced by gestational age during the first two days of postnatal life. Thereafter, the values increase very rapidly in the first week of life, concentrations being the same as in adults by about 10 months. In 66 of 78 cases of severe bacterial infections, orosomucoid concentrations were above normal. Evidently, serum orosomucoid constitutes an useful index in diagnosis and monitoring of bacterial infections in the neonatal period.

Adult↗
PubMed1980

Serum copper and zinc concentration in premature and small-for-date infants.

Serum copper (Cu) and zinc (Zn) concentrations were measured in neonates with an appropriate birth weight for gestational age (AGA) and in small-for-gestational age infants. At 7 days of age, there was a positive correlation between serum Cu concentration and gestational age (GA) (r = 0.63; P < 0.001) and a negative correlation between Zn concentration and GA (r = 0.62; P < 0.01). At 7 days of age, the mean (+/- S.E.) concentrations in AGA full-term infants (Cu, 79 +/- 8 microgram/dl; Zn, 84 +/- 4) were similar to those in small-for-gestational age, full-term infants (Cu, 78 +/- 6 microgram/dl; Zn, 85 +/- 12). In preterm infants, there was also no difference between AGA and small-for-gestational age infants. In 23 AGA infants with a birth weight of less than 1500 g, serum Cu concentration increased from 51 +/- 7 microgram/dl at the age of 7 days to 86 +/- 7 microgram/dl at the age of 60 days (paired t-test: P < 0.05) whereas serum Zn concentration decreased from 149 +/- 9 to 91 +/- 5 microgram/dl (P < 0.01). A positive correlation was found between serum Zn concentration and daily intake of Zn (n = 39; r = 0.3458; P < 0.05), but no correlation was found for serum Cu concentration. The evolution of serum Cu and Zn concentration with total age (GA + postnatal age) in the infants with a low birth weight (i.e., < 1500 g) was similar to the evolution with GA.

Animals↗
PubMedDate not supplied

Serum procalcitonin rise is only slight in two cases of disseminated aspergillosis.

High serum concentrations of procalcitonin (PCT) have been found during bacterial and parasitic infections. This is a report of two cases of disseminated aspergillosis with moderate PCT increase in two 14-year-old girls after bone marrow transplantation (BMT) for myelodysplastic syndrome and Fanconi's anemia, respectively. In contrast, the important rise of serum CRP observed in these patients tends to demonstrate that the synthesis of these two proteins is under different control mechanisms.

Adolescent↗
PubMedDate not supplied

[The normal protein profile in newborn infants].

The authors report the results of the immunonephelometric determination of 9 proteins in the serum of 74 newborns: CRP, orosomucoid, haptoglobin, alpha-1-antitrypsin, C3, C4, transferrin, prealbumin and apo B have been studied. The influence of gestational and postnatal ages are shown. Results are compared with those of the literature. The respective role of the transfer of plasma proteins from mother to foetus and of foetal synthesis in the concentration of a protein in the serum of a neonate is discussed.

Apolipoproteins B↗
PubMedDate not supplied

[Immunochemical methods for measuring specific proteins].

Immunochemical methods are based on the antigen-antibody reaction. Two groups of techniques can be made: group I in which the visualization of the antigen-antibody reaction is direct (radial immunodiffusion, immunonephelometry, immunoturbidimetry...), group II which needs a label to detect the complex (radioimmuno assay, immunoenzymology). The characteristics of the principal methods (time needed, sensitivity, apparatus, applications) and their causes of error are compared. Thanks to their precision, the possibility of micromethod and their rapidity, immunonephelometric technics are recommended in pediatrics.

Antigen-Antibody Complex↗
PubMedDate not supplied

[Course of inflammatory and nutrition proteins in bacterial infections in newborn infants].

A study of 214 neonates (with 87 premature infants) reveals that C-reactive protein (CRP), orosomucoid and prealbumin are the most interesting proteins for the diagnosis of neonatal sepsis and for studying its follow-up. Orosomucoid is high in 85% of bacterial infections and CRP in 75%. Early type strep B infections give often false negative results. The evolution of CRP and of prealbumin corresponds to the effects of treatment and the evolution of orosomucoid is parallel to the healing of the patients. The ratio orosomucoid/prealbumin allows an earlier appreciation of the healing.

Bacterial Infections↗