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Biomedical subjects

F Biancari

Publications and source records attributed to F Biancari.

At least 73 records · Page 4Linked to original sources

Stent grafting for abdominal aortic aneurysms in Finland--a feasibility study.

BACKGROUND AND AIMS: Endovascular repair of abdominal aortic aneurysms (AAA) is a feasible procedure in selected patients. In order to assess how many AAAs are suitable for such a procedure, a survey has been conducted in Helsinki, Kuopio, and Tampere University Hospitals. MATERIAL AND METHODS: AAAs having a maximum diameter of 45 mm or more at ultrasonography were included for further evaluation and assessment by angiography and/or spiral CT angiography to determine the length and width of infrarenal aneurysmal neck as well as the dimensions of the distal abdominal aorta and iliac arteries. RESULTS: Among a total of 75 patients with AAA examined in three centres, ultrasonography overestimated the size of the aneurysm in 12 cases that were demonstrated by angiography and CT to have a diameter of less than 45 mm. Among those patients with larger aneurysms, 17 (27%) were suitable for endovascular repair. Stent grafting has been performed in 10 patients until May, 1997. Perigraft leakage occurred in one patient who required the insertion of an additional collar stent graft. CONCLUSIONS: Large numbers of suitable patients are not easy to find but, by performing joint screening in Finland, epidemiological data on suitable aneurysms and improving co-operation between centres can be achieved. Therefore, it would be wise to centralise endovascular repair of AAA.

Aortic Aneurysm, Abdominal↗

Biofragmentable anastomosis ring in emergency surgery.

BACKGROUND: The biofragmentable anastomosis ring (BAR) proved its usefulness in elective bowel surgery. AIMS: To verify the validity of the BAR in restoring bowel continuity in emergency. MATERIAL AND METHODS: The authors retrospectively evaluated the results of 62 intestinal resections and primary anastomoses with the BAR performed in 53 consecutive patients undergoing single-stage surgery for acute abdomen. No patients had either preoperative bowel preparation or intraoperative intestinal lavage. RESULTS: No proximal ileostomy or colostomy was used. A single anastomosis was made in 47 patients, while the remaining 6 patients underwent multiple intestinal resections with primary anastomoses. Forty-nine of the 53 patients had an uneventful recovery. Anastomotic leakage occurred in 2 patients (3.2%) operated on for an obstructing carcinoma of the left colon. One patient was successfully treated with a period of total parenteral nutrition, whereas the other required reoperation for a complete anastomotic leak due to failed closure of the device which was re-inserted successfully. Two patients (3.7%) died postoperatively of myocardial infarction and hepato-renal syndrome. CONCLUSIONS: Although this is a non-randomised trial, these results suggest that the BAR can be employed effectively in the emergency setting, even when single-stage intestinal surgery is performed.

Abdomen, Acute↗

[Surgery of differentiated cancer of the thyroid].

A retrospective study on patients with differentiated thyroid carcinoma operated on at the 3rd Department of General Surgery of the University "La Sapienza" of Rome from 1970 to 1996 was performed. In 709 patients total thyroidectomy was performed as the minimal procedure acceptable, while 19 patients had subtotal thyroidectomy out of necessity. A functional ipsilateral or bilateral lymphnectomy of the neck was performed in 256 cases. This wider operation is indicated in the presence of metastatic lymph nodes and on principle in patients older than forty-five years in which at least another risk factor is present. Long term follow-up (12 years) was assured in 302 patients and the survival rate was 92% independently from the histotype (papillary or follicular). The survival rate of a group of 120 patients (80 with papillary and 40 with follicular carcinoma) was analyzed in relation to the risk factors. This group analysis demonstrated a very low mortality rate in patients with low risk index and an increased rate in patients with a high risk index.

Carcinoma↗

Late onset of myasthenia gravis after total resection of thymoma: report of two cases.

The authors report two patients presenting myasthenia gravis, respectively, 4 years and 2 months, and 6 years and 7 months after total resection of thymoma. Computed tomographic scan and magnetic resonance imaging did not show any signs of recurrent or metastatic thymoma. Pyridostigmine bromide was successfully administered in both patients. The late onset of autoimmune disorders should be kept in mind as possible and, sometimes, fatal complications of surgical treatment for thymoma. In all cases, recurrent or metastatic thymoma should be ruled out because reoperation may be effective even in the treatment of myasthenia gravis.

Adult↗

[Cystic nephroma].

The authors describe a rare case of cystic nephroma treated by partial surgical excision. Because there is concurrence in the association of multilocular cysts with Wilms tumors and others tumors of the kidney, it is underlined the importance of a differential diagnosis to avoid nephrectomy for treatment of this benign neoplasm.

Adult↗

Reoperation for recurrent thymoma: experience in seven patients and review of the literature.

The authors analysed retrospectively seven patients who underwent reoperation for recurrent thymoma. Patients have been categorised according to the classification of thymic epithelial tumours proposed by Masaoka et al. (29). In addition, patients have been subgrouped according to pleural invasion as defined by Haniuda et al. (15). Thus three substages were proposed as follows: p0-no adhesion to the mediastinal pleura; p1-patients with fibrous adhesion to the mediastinal pleura without microscopic invasion; p2-patients with microscopic invasion into the mediastinal pleura. At the initial operation, two patients were in Stage I, four Stage II, and one in Stage III. All Stage I patients were classified as p1, and of the four patients in Stage II one was classified as p0 and three patients as p2. One Stage III patient was classified as p2. Disease-free survival ranged from two years and four months to 20 years and two months. All patients underwent reoperation without preoperative treatment. Recurrent disease was aggressively resected from the pleura in six patients, mediastinum in four patients, lung in three patients, and diaphragm in three patients. Two patients refused further postoperative treatment. Adjuvant radiotherapy was administered to five patients; chemotherapy was added to the postoperative treatment of three patients with more advanced recurrent disease. Five patients were alive, free from any detectable tumour recurrence, one year and nine months to five years and four months after reoperation. In two patients with exacerbation of myasthenia gravis, reoperation was followed by complete remission of myasthenic symptoms. One patient died of post-radiation pulmonary fibrosis 13 months after reoperation, and one patient died of disease two years and two months after the second operation. Our findings indicate that an aggressive surgical approach to recurrent thymoma is justified and can be followed by prolonged disease-free survival.

Adult↗

[Endoesophageal ultrasonography in the staging of esophageal carcinoma].

Staging of esophageal cancer is fundamental for treatment and prognosis of this tumour. At present, barium swallow and computed tomography (CT) are the most utilized diagnostic modalities. In recent years Endoscopic Ultrasonography (EUS) has been employed for this purpose. We retrospectively compared the results of EUS and CT staging of 33 selected patients with postsurgical stage. EUS allowed a correct diagnosis of parietal invasion in 82% of cases vs 67% obtained by CT. At the same time, EUS diagnosed correctly 85% of metastatic lymph nodes vs 64% reached by CT. We believe that EUS, in combination with CT, is an appropriate modality for the staging of esophageal cancer.

Esophageal Neoplasms↗

Benign vascular tumours of the Mediastinum: presentation of three cases and review of the literature.

Two patients with epithelioid haemangioendothelioma and one patient with multiple cavernous haemangiomas of the mediastinum, pharynx and larynx, are herein presented. Haemothorax as initial manifestation of the tumour was observed in one of them. Epithelioid haemangioendotheliomas were radically removed in both cases. Because of the absence of a well defined capsule and the huge extension, the cavernous mediastinal haemangioma was not resected. However the patient was successfully treated by administration of corticosteroids. Clinicopathologic characteristics of these benign forms of vascular tumours are discussed and treatment options are suggested.

Adolescent↗

[Nephro-jejunal fistula associated with nephro-cutaneous fistula].

The development of a renal fistula is a rare event which results from an acute or chronic inflammatory process in the kidney. The authors report a very rare case of nephrojejunal and nephro-cutaneous fistulas due to acute and chronic pyelonephritis in a patient with staghorn stones of the left kidney.

Aged↗