Staphylococcal brain abscess following hematogenous seeding of an intracerebral hematoma.
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Biomedical subjects
Publications and source records attributed to F Bert.
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We performed a 2-year microbiological study of specimens of sinus fluid recovered from patients with suspected nosocomial sinusitis in six intensive care units. Over that period, 103 cases of sinusitis were documented by positive culture. The number of cases varied widely from one unit to another and was particularly high in the neurosurgical unit. Cultures were often polymicrobial. The main pathogens were Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacteriaceae. Streptococcus pneumoniae and Haemophilus influenzae were far less frequently isolated. Anaerobes and yeasts were often associated with aerobic bacteria. The pathogen involved was also recovered from bronchopulmonary samples in 50 patients and from blood cultures in seven patients.
Polyacrylamide-agarose gel electrophoresis was used to study polymorphism of lactate dehydrogenase (LDH), nucleoside phosphorylase (NSP), phosphoglucose isomerase (PGI), hydroxybutyrate dehydrogenase (HBD), adenylate kinase (ADK) and esterases of 44 strains of Streptococcus pyogenes, 25 group G streptococcal strains, 11 "S. equisimilis" strains, seven S. dysgalactiae strains, four S. canis strains, three S. equi strains and seven S. zooepidemicus strains. Analysis of LDH, NSP, PGI, HBD and ADK provided valuable interspecies differentiation, by showing that four groups of strains corresponded to the four known DNA homology groups. Esterases showed greater intraspecies variation than the other enzymes. The combined analysis of the six enzymes indicated 31 zymotypes among S. pyogenes, 14 in group G streptococci and 11 in "S. equisimilis" strains. This was shown to be an effective technique for typing pyogenic streptococci.
We report a case of a brain abscess due to Bacillus macerans and Clostridium sp. following a penetrating periorbital injury by a wooden branch. Intracranial penetration by and retention of a foreign body were not suspected initially, and neurological symptoms developed only 2.5 months later. Previously reported cases of brain abscesses due to Bacillus species are reviewed.
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The susceptibility to antibiotics of 1367 non-replicate strains of Pseudomonas aeruginosa isolated at Beaujon Hospital between 1990 and 1992 was investigated and compared with the serogroup O and the strain origin (ward, sample). Five betalactam resistance patterns were distinguished according to susceptibility to ticarcillin, piperacillin, ceftazidime and aztreonam,: 1 = SSSS, 2 = RRSS, 3 = RRRR, 4 = RSSR, 5 = RRSR. The other antibiotics studied were imipenem, tobramycin, amikacin, ciprofloxacin and fosfomycin. Resistance to all antibiotics, fosfomycin excepted, was higher in intensive care units than in other wards. The respective frequencies of the phenotypes were: 70.3%, 4.3%, 11.8%, 10.2% and 3.4%. The frequency of pattern 3 steadily increased between 1990 and 1992 at the expense of pattern 1, whereas patterns 2, 4 and 5 remained stable. The most common serogroups were O6 (15.8%), O11 (14.5%) and O1 (9.9%). The O11 strains were more widespread in intensive care units than in other wards and were more resistant to antibiotics. Most of the O12 strains displayed pattern 2 and were highly resistant to antibiotics.
Meat regulations also involve game inspection. The previous publications on the one hand dealt with the regulations and their practice concerning game intended for slaughter, especially the control of fences and the gaining of meat. On the other hand regulations concerning game hunted for food (Deer: Red deer, Sika deer, Fallow deer, Roe deer; Horned ungulates: European mouflon, Chamois; Wild boar; European hare; European rabbit; game such as Badger and Raccoon) and regulations to be observed by hunters, mainly for the gaining of meat were discussed. The recent publication regarded meat inspection (routine inspection) of slaughter game. The following publication deals with meat inspection (routine inspection) of game hunted for food and with meat inspection (additional inspection) of slaughtered game as well as game hunted for food.
Meat regulations also involve game inspection. On the one hand the previous publications dealt with the regulations and their practice concerning game intended for slaughter, especially the control of fences and the gaining of meat. On the other hand regulations concerning game hunted for food (deer: red deer, sika deer, fallow deer, roe deer; horned ungulates: European mufflon, chamois; wild boar; European hare; European rabbit; game such as badger and raccoon) and regulations to be observed by hunters, mainly for the gaining of meat were discussed. At the beginning the following publication completes the previous ones concerning game hunted for food and later deals with the meat inspection of slaughtered game.
Meat regulations also involve game inspection. This publication deals with the regulations concerning furred game intended for slaughter and furred game hunted for food.
Meat regulations also involve game inspection. The previous publication mainly dealt with the regulations and their practice concerning game intended for slaughter. The following publication deals with game hunted for food (deer: red deer, sika deer, fallow deer, roe deer; horned ungulates: european mufflon, chamois; wild boar; european hare; european rabbit) and also game such as the badger and the raccoon.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
An 86-year-old woman with a history of metastatic breast cancer developed two episodes of streptococcal bacteraemia and erysipelas separated by an interval of 3 months. The isolates belonged to Lancefield group A but were biochemically identified as Streptococcus equisimilis. The similarity of the two isolates was established by DNA macrorestriction analysis and pulsed-field gel electrophoresis, indicating that the second episode was due to relapse and not reinfection.
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The in vitro activity of piperacillin, cefoperazone, cefsulodin, ceftazidime, aztreonam and imipenem was studied against 44 isolates of Pseudomonas aeruginosa with 'intrinsic' resistance to ticarcillin in comparison with 20 ticarcillin-susceptible strains, by MIC determination and the disk diffusion test. The activity of the antibiotics, imipenem excepted, against the resistant strains was reduced when compared to the susceptible strains. The most significant reduction was found for aztreonam and the least significant for ceftazidime. When considering the breakpoints, all strains were intermediate with aztreonam and cefoperazone, but most of them remained susceptible to ceftazidime, piperacillin and cefsulodin.
The in vitro activities of cefepime and cefpirome against 44 intrinsically ticarcillin-resistant strains of Pseudomonas aeruginosa were compared to their activities against 20 ticarcillin-susceptible strains by MIC determination and the disk test. Time-killing curves were constructed for piperacillin, ceftazidime, cefepime and cefpirome against two susceptible and two resistant strains. The activities of cefepime and cefpirome against the resistant strains were impaired, and most of the strains were of intermediate sensitivity to these agents. The time-killing curves of the four beta-lactams were similar, with a modest decline in viable cell counts over the first 6 h followed by regrowth. There was no difference between the susceptible and resistant strains.