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Biomedical subjects

F Beccia

Publications and source records attributed to F Beccia.

At least 19 recordsLinked to original sources

The brain amino acid pattern in experimental coma due to phenytoin in guinea pigs.

An experimental study was carried out on 50 guinea pigs to evaluate the amino acid pattern in the whole brain after a toxic dose of phenytoin (1 g . kg-1 body wt). One group of 25 guinea pigs was treated with the drug which made them comatose, and their brains removed by craniotomy and frozen in liquid nitrogen; 25 guinea pigs were used as a control group. The brain amino acid pattern was determined by ion-exchange chromatography. All the amino acids, except threonine and methionine, decreased. Hypotheses about the particular cerebral metabolic pathways involved are discussed.

Amino Acids

The effect of five drugs in coma doses on neurotransmitter amino acids in the brains of guinea pigs.

The study has been carried out in order to investigate the effects of some drugs in coma doses on the concentration in brain of some amino acids involved in brain function. Six groups of 25 guinea pigs each were utilized. In each of the five groups a subcutaneous dose of diazepam, flunitrazepam, phenobarbital, phenytoin or alfaxalone, was injected and one group was utilized as control. Some neurotransmitter amino acids (glutamate, aspartate, glycine and taurine) and precursors of neurotransmitters (phenylalanine and tyrosine) were determined in brain preparations. The results are discussed.

Amino Acids

[Anesthesiological problems in tracheal resection operations. Clinical contribution].

The anaesthesia technique adopted for tracheal resection in a woman patient with tracheal stenosis secondary to prolonged intubation is reported. The criteria underlying the choice of anaesthesia are outlined. Various anaesthesiological techniques are discussed and solutions illustrated in relation to the location of tracheal stenosis.

Anesthesia

[Our experience with peridural anesthesia in labor].

A clinical study has been carried out on 86 child-bearing mothers, continuous lumbar peridural block being employed, in the light of personal experience, to induce analgesia during labour. The results were positive on the whole as regards duration and the algogenous intensity measured during the dilatation phase and during expulsion.

Adult

[Lumbar epidural anesthesia in peripheral arteriography].

A brief survey of the difficulties associated with the intra-arterial administration of contrast media during peripheral arteriography is followed by an assessment of anaesthesiological and arteriographic results obtained with lumbar peridural anaesthesia in a group of patients. Complete analgesia, block of the sympathic, and motor block gave particular assistance in the securing of optimum definition of the radiographical picture of the peripheral circulation. These and other advantages offered by peridural anaesthesia suggest that it is a valid technique for peripheral arteriography.

Anesthesia, Epidural

[Cardiac contusion in closed injuries of the thorax].

Cardiac contusion is a fairly frequent clinical event in closed chest traumas. The diagnostic problems it involves influence prognosis in these patients and, in effect, prevention, speedy recognition and early treatment of the complications of cardiac contusion are essential for therapy. Here the incidence of cardiac contusion in a group of patients with closed chest trauma is analysed and the clinical, diagnostic and therapeutic aspects are examined.

Adolescent

[Effects of CT 1341 (althesin) anesthesia on human adrenal cortical function].

Following a short introduction on the stress action of anaesthetics, the effects of anaesthesia with CT 1341 (Althesin) on cortico-adrenal function was investigated, with an evaluation of cortisone plasma concentration. The results obtained in 10 patients point to an increase in plasma cortisone after 30 and 150 minutes of anaesthesia. The discussion hypothesizes the possible influences of the anaesthetic on the hypophyseal-adrenal axis.

Adolescent

[Gaseous myelography. Accidents and complications. Case reports].

Attention is called to the risks of gas myelography and two cases of complications are described. One of these, observed personally, was fatal and its possible pathogenetic mechanisms are illustrated. Stress is laid on certain rules and precautions that should be respected in radiological and anaesthesiological practice. Insufflation pressure and volumes of injected air deserve particular attention and scrupulous intraoperative control cut of vital parameters must be carried and appropriate attention paid to patient hydration during the postoperative period.

Adult