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Biomedical subjects

F Balogh

Publications and source records attributed to F Balogh.

At least 91 records · Page 5Linked to original sources

Estimated frequency of acute and chronic renal insufficiencies in a Transdanubian region of Hungary.

The literature on the incidence of chronic and acute renal insufficiency is reviewed and the results of own investigations in an area with a population of 1,560,000 are presented. Data were collected in questionnaires. The yearly incidence of patients with chronic uraemia requiring active therapy was estimated at 33 per 1 million population. The number of acute cases was 45 per million. The necessity of increasing the dialysis capacity is stressed. The importance of peritoneal dialysis in the therapy of uraemia cases which do not meet the requirements of the acute and chronic dialysis programmes is emphasized.

Acute Kidney Injury↗

Treatment of prostatic cancer with Estracyt (estramustine phosphate).

The experience gained with Estracyt, kindly supplied by AB LEO, Sweden, is reported. On the basis of former data in the literature we only used the drug in estrogen resistant and advanced cases. Estracyt (estramustine phosphate) is a nitrogen mustard derivative of the urethan type, attached to oestradiol-17-phosphate. In histologically verified cases, it was administered in daily doses of 300 mg intravenously for three weeks, followed by maintenance doses of 300 mg a week in tablets for three months. During treatment, liver and bone marrow function was checked systematically. The changes in morphological picture were studied by means of biopsies during and at the end of treatment. In agreement with the data in the literature a favourable effect was observed in estrogen resistant patients, with no toxic effect whatever on the bone marrow. At the same time GOT and GPT and BSP retention examinations demonstrated a hepatotoxic side effect. The pathological values returned to normal after withdrawal of the drug. Histological examinations showed that the tumour cells had changed but failed to disappear after treatment.

Clinical Trials as Topic↗

[Resection syndrome following transurethral resection of the prostate].

The essence and clinical aspects of the resection syndrome occurring in association with transuretheral prostate resection and the possiblity of determining the direction of the absorption of the washing solution are discussed. By means of radioisotope tests a direct correlation was detected between the extent of the haemorrhage and the intravasation of the washing solution. Great importance is ascribed to the vesico-renal reflux often occurring during resection, which might have a major role in the development of post-resectional pyelonephritis.

Aged↗