[Influence of sanitary and antibiotic regimes on the bacterial flora of premature and newborn infants under hospital care].
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Biomedical subjects
Publications and source records attributed to F B Spencker.
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In a newborn after delivery by vacuum extraction and after application of a scalp electrode for fetal monitoring a cephalhematoma followed by infection due to E. coli was observed.--It was treated by antibiotics and incision. In a brief review of the literature the problems of the origin, diagnostic, and therapy of infected cephalhematoma are discussed. For the detection of local infection and bacteremia the authors emphasize careful bacteriological examinations (aspirate from hematoma, blood culture) as well as radiographs of the skull. The treatment of infected cephalhematoma must consist of antimicrobial chemotherapy and incision of the local process.
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The authors report on a case of sepsis due to E. coli in a newborn baby with galactose intolerance. The immature immunological state of the newborn child in combination with a disorder of galactose metabolism obviously favour the development of bacterial infections. Galactose-free formulas should be applied quickly together with an adequate antibiotic therapy in the case of newborn babies with suspected bacterial infection. The prognosis may be influenced favourably by early clarification of the cause of severe impairment including jaundice, vomiting, loss of weight and somnolence in the first three weeks of life.
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After introductory explanations the following topics are treated: acute respiratory diseases, virus infections of the central nervous system and virus infections of the intestine. In the last paragraph the present state of virus-diagnostic possibilities is described. From this is derived that the routine use of modern virus diagnostics brings great advantages for the clinician. The intensive construction of virological laboratories for the treatment of patients is emphasized.