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Biomedical subjects

F B Bailie

Publications and source records attributed to F B Bailie.

12 recordsLinked to original sources

Malignant melanoma in a skin graft: burn scar neoplasm or a transferred melanoma?

Malignant melanomas (MM) arising in burn scars are rare with 16 cases previously reported. Malignant melanomas arising on skin grafts are even more rare with only two cases reported. We present the case of MM arising on a burned area that had been previously grafted with a split thickness skin graft. A 19-year-old patient sustained 20% burns in a road traffic accident. The burned areas were debrided and skin grafted. Six months later, the patient developed MM on the left calf (an area that was burned and grafted). The tumour was excised with wide margins. Six months following the excision of the MM, the patient started to develop multiple dysplastic naevi in the skin grafted burned areas. In the present case, the main question to be answered is whether the MM arose from the donor or the recipient site of the split thickness skin graft. After thorough discussion of the two options and reviewing the literature, the authors believe that the MM and the atypical naevi were transferred to the recipient site with the skin graft. Therefore, it is suggested that in the process of harvesting skin grafts, any pre-existing naevi should be avoided or removed, and if this is not feasible, should be recorded in detail in the operation notes. Also, patients at discharge should be advised that any change in the appearance of the grafts or any new lesions in the engrafted areas should be reported to their physicians.

Adult↗

Omental transposition flap for gross locally recurrent breast cancer.

BACKGROUND: The omentum has been employed to cover the defect produced after resection of gross breast cancer recurrence for nearly three decades. METHODS: A series of 11 patients undergoing omental transposition flap for very wide resection of gross local recurrence (LR) of breast cancer is reported. The median age was 39 years, with a short interval (median = 21 months) from the treatment of the primary tumour to LR. Local recurrence was gross and predominantly inflammatory. RESULTS: All except one patient had lymphovascular invasion in the recurrent tumour. The omental graft was 100% viable but one patient required re-application of further split-thickness skin graft. The mean hospital stay was 16 days. Two cases of seroma formation were encountered. New recurrence developed around the periphery of the flap in eight patients after a median duration of local control of only 2.5 months. Eight patients died with metastatic disease after a median period of 6 months, six patients with uncontrolled local disease. Five patients were free from LR in over half of their remaining period of life. CONCLUSION: Omentoplasty is a safe and reliable procedure but the length of palliation achieved is often far from satisfactory.

Adult↗

Petrol--something nasty in the woodshed? A review of gasoline-related burns in a British burns unit.

Petrol (gasoline) is probably the fuel most easily available and widely in use today. Indeed, most households have a can lurking in the garden shed or basement for domestic use. It's chemical properties make it a highly explosive as well as a combustible fluid, a fact that is sometimes poorly appreciated. We looked at the incidence of petrol-related burns seen in our unit over a 2-year period. Nearly 33 per cent of the adult male admissions were petrol-related and 16 per cent were in children under the age of 16 years. The commonest cause of injury was attempting to start or accelerate a bonfire (38 per cent) with only a small number of barbecue injuries (4 per cent). Petrol causes a significant number of burn injuries a year, and particularly worrying were the number of children injured. However, we feel there is a need for greater public education and perhaps stricter control of this substance.

Adolescent↗

Survey of analgesia regimens in burns centres in the UK.

A survey of the analgesia regimens used in burns units throughout the UK was performed. Continuous intravenous opiate infusions remain the mainstay for providing pain relief in patients in severe pain as a result of burn injuries. Other methods include: patient-controlled analgesia in appropriate patients, bolus doses of opiates combined with Entonox for control of peaks of pain and a wide variety of oral analgesics for less painful burn injuries.

Analgesia↗

Acute haemodilution in surgery for burns: a preliminary report.

Blood loss is a major problem in the management of patients with burns treated by early excision and grafting. Acute normovolaemic haemodilution has been successfully used in cardiac surgery for many years but has not been reported previously in surgery for burns. The technique has been used in six patients with burns undergoing early excision and grafting, with no obvious morbidity and an apparent reduction in homologous blood requirements.

Adolescent↗

Serious group A streptococcal infections complicating cryotherapy to lip haemangiomas.

Cryotherapy is a safe and effective way of treating haemangiomas of the oval cavity and lips without complications in adults in a reported series. Two cases of serious group A streptococcal infection after cryotherapy in two children are reported. In conclusion it is likely that these children were undiagnosed carriers for the organism. Pre-operative nasopharyngeal swabs would have identified this and prevented the complications which occurred.

Child, Preschool↗

Infective cutaneous gangrene--urgency in diagnosis and treatment.

Many descriptions of infective cutaneous gangrene have been published under a variety of names. The classification adopted by Ledingham and Tehrani is illustrated by 4 cases seen in the Stoke Mandeville Hospital. Although the incidence is high in Eastern countries, infective cutaneous gangrene is uncommon in the Western hemisphere owing to a difference in geographic pathology. Early and delayed management is described, stressing that early diagnosis and aggressive treatment is required, ideally by a team consisting of a microbiologist and plastic and general surgeons. There is a substantial risk associated with the failure to diagnose and treat this condition. Mortality rates and prognosis are reviewed.

Adolescent↗

Aplasia cutis congenita of neck and shoulder requiring a skin graft: a case report.

A case of aplasia cutis congenita in a neonate is presented, involving absence of skin over the left side of the neck and shoulder. There were no associated abnormalities and the defect was successfully skin grafted on the ninth day after birth. Several possible causes have been adduced to explain amnionitis as a result of intrauterine injury and amniotic bands but a strong factor in this case was felt to be maternal chickenpox contracted during the fifteenth week of pregnancy.

Dermatologic Surgical Procedures↗