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Biomedical subjects

F Attie

Publications and source records attributed to F Attie.

At least 91 records · Page 5Linked to original sources

[Axial angiography in tetralogy of Fallot].

We studied 15 patients with the diagnosis of tetralogy of Fallot by means of conventional and axial angiocardiography. Axial studies were performed in the four chamber view (vertical and horizontal X-ray beams) and in the sitting-up view (vertical X-ray beam). With the right ventriculogram we analyzed the anatomic characteristics of this chamber, infundibular stenosis and the pulmonary branches. Left ventriculograms were performed in order to rule out other less common associated defects. In the sitting-up view we analyzed the characteristics of the right ventricular infundibulum and the pulmonary valve, artery and branches. None of our patients underwent aortography or coronary artery angiography. We conclude that utilization of axial angiocardiography is useful in tetralogy of Fallot because it permits a better appreciation of the anatomy of this malformation, the presence or absence of stenosis of the pulmonary branches and other less frequent associated defects. Aortography or coronary artery angiography must be performed in children in which the anatomy of the coronary arteries cannot be determined by either left or right ventriculograms.

Angiocardiography↗

[Isolated double-chamber right ventricle. Report of 2 cases].

Two cases of double-chambered right ventricle without ventricular septal defect are presented. Both were diagnosed with the hemodynamic study and underwent successful surgical repair. We discuss the probable embryologic development and the diagnostic procedures of this malformation.

Adolescent↗

[The electrocardiogram of the normal child].

The EKG findings of 202 normal children, aged 1 month to 10 years were reviewed in order to determine criteria for diagnosis of ventricular hypertrophy. QRS voltage in right and left precordial leads are very variable and do not constitute adequate criteria for the diagnosis of ventricular hypertrophy the same is true with QRS duration, which increases progressively from 50 to 60 msec from the first to the fourth year of life, and to 70 msec over that age. The values found are smaller than those previously reported in the literature. Measurement of initial intrinsicoid deflection time in leads VI, aVF and V6 apparently have important clinical significance. This is a constant finding in normal hearts in lead VI, where deflection time is 18 to 20 msec. Therefore, times above 25 to 30 msec are sugestive of right ventricular hypertrophy when RBBB is not present. Intrinsicoid deflection time in lead V6 in children under one year of age was 20 msec, while between age one and ten it varied between 20 and 31 msec. Such variations show how left ventricular tissue increases after the first years of life, and also that times above 5 msec over those found for any age group are indicative of left ventricular hypertrophy.

Age Factors↗

[Fibrous fixed subaortic stenosis].

Fifty eight patients with isolated with discrete subaortic stenosis or in association with just another heart defect, were studied between 1961 and 1980. The age range was between 2 and 42 years. The evaluation of each case was done according to clinical manifestations, systolic overloading of the left ventricle and the amount of the systolic gradient. There is a poor correlation between the clinical, electrocardiographic and hemodynamic parameters according to the student t test in the preoperative evaluation. Forty-one patients were operated, two of them died in the early post-operative period. There was a good clinical evolution with significant values comparing pre and post-operative symptoms. The decrease in the systolic gradient in 26 cases after surgery was significative (p less than or equal to 0.005). Based on the natural history of this malformation and on the results obtained with the surgical treatment, we may conclude that there is surgical indication once the diagnosis is made, because this malformation has a completely different evolution compared with other forms of congenital aortic stenosis.

Adolescent↗

[Infectious endocarditis in children].

he recent advances in surgical treatment of congenital heart disease, permits the survival of those cases to adult life. Infective endocarditis in the childhood is becoming increasingly important. We studied 32 cases in the pediatric cardiology ward at the INC between 1977 and 1981. There was a male predominance of 62.5%. Rheumatic heart disease (40.7%), congenital heart disease (15.6%) and postoperative cases (43.7%) were the underlying conditions. There was an average time of 43 days delay from the first symptom to diagnosis. Blood cultures were taken in 29 cases (90.6%). Only half of them were positive. Staphylococcus and streptococcus were the commonest isolates. Peripheral and pulmonary embolism (11 cases-34.4%) were the most frequent complications. In those cases with negative blood culture the most successful antibiotic combination was ampicillin or oxacillin plus aminoglucosides (56%). There were 17 deaths (53%).

Adolescent↗

[Double outlet of the right ventricle with anterior aorta to the left of the pulmonary artery in situs solitus].

Two cases of double outlet of the right ventricle with an anterior aorta to the left of the pulmonary artery are described. Both in situs solitus. One had an anterior interventricular communication, and other had a middle posterior communication. The importance of the aortic component of the second sound is analyzed with regard to its localization and intensity. An analysis is also made of the morphology of the cardiac silhouette and the peculiarities of the electrocardiogram as diagnostic aides in the malformation. Considerations are made of the distinct theories which explain the malformation. It is clearly shown that a correct diagnosis is necessary since this cardiopathy may be treated surgically.

Abnormalities, Multiple↗

[Prevention of recurrence of rheumatic cardiopathy in 564 patients].

In a group of 564 patients with rheumatic heart disease seen in the period from 1971 to 1975, who were under benzatinic prophylaxis, 23% were seen in the clinic and 77% at home. The object of this revision is to analyze the latter group in order to obtain the frequency of pharyngoamigdaline infections, and of relapses. 1. During the observation, those patients who did not present pharyngeal infections had no relapses. On the other hand, all relapses were observed in those patients who presented infections. 2. Those patients who carried out the prophylaxis incorrectly and who also presented pharyngeal infections, had almost twice the percentage of relapses as those who carried out the prophylaxis correctly. 3. In the group with effective prophylaxis, including those cases with or without pharyngeal infection, 5% had recurrences. In the group with ineffective prophylaxis, 16% had relapses. 4. Those patients with subsequent attacks doubled the percentage of relapses in comparison with those with initial attacks. 5. The plurivalvular patients have a higher frequency of recurrences than the univalvular patients. 6. During the first year of post-attack prophylaxis, the incidence of relapses is only 1.7%, in comparison with the following years in which there is a higher incidence of around 10%. 7. The total number of recurrences in 564 patients was 8%.

Adolescent↗

[Superoinferior ventricles].

We describe two patients with under-and-over ventricles. Both were diagnosed angiographically. One has atrial, situs solitus with discordant atrioventricular and ventriculoarterial connections and a ventricular septal defect. The second has atrial situs inversus with concordant atrioventricular connections and double-outlet right ventricle. We review the literature and analyze the probable embryogenesis of the malformation.

Adult↗

[Anatomy of atrioventricular discordances].

Nineteen anatomic specimens were revised, 10 in situs solitus and 9 in situs inversus. The type of atrioventricular connection, atrioventricular relation, the characteristics of atrioventricular valves and ventricular cavities, the atrial and ventricular septa, the conducting tissue, the type of arterio-ventricular connections, the anatomy of the coronary arteries and associated defects were studied. The anatomic features of the ventricular cavities differ from those in the normal heart with respect to the orientation of the atrio-ventricular valve rings, the implantation of the papillary muscles in both ventricles and the extention of the membranous septum. The most frequently found type of arterioventricular connection was discordant, followed by double-outlet right ventricle, concordant connections and finally single outlet. We did not find any case of double-outlet left ventricle. It is important to know the anatomy of the conducting tissue that is in close contact with the ventricular septal defects, the most common associated anomaly in our series, and with infundibular pulmonary stenosis.

Heart Atria↗

[Electrocardiographic diagnosis in atrioventricular discordance].

The ECG of 37 patients with atrioventricular discordance were studied and divided in two main groups: I) Situs solitus and II) situs inversus, either a) without associated defects or b) with associated defects. It was concluded: 1) The first vector of ventricular activation, oriented in the same sense of that of atrial activation is a fundamental diagnostic sign; 2) The preponderance of anatomical right ventricle, leads to the diagnosis of unassociated defects; 3) The recognition of biventricular hypertrophy obliges to the diagnosis of associated defects; 4) The AQRS deviation and the shortening in duration of the local electrical systole help to recognized the hypertrofied ventricle and its overload; 5) The presence of right bundle branch block is not in relation to the degree of overloading; 6) The primary alterations of ventricular repolarization are univocal signs of myocardial damage.

Adolescent↗

[Management of pulmonary stenosis in the correction of the tetralogy of Fallot].

Successful surgical correction of (la estenosis pulmonar en la tetralogía de Fallot), requires that the postoperative ratio between the (right ventricular pressure) and (left ventricular pressure) (PVD/PVI) be less than 0.70. By measuring the ring diameter and pulmonary branch on relation to the (superficie corporal) it is possible to predict the outcome of this ratio and therefore indicate whether or not it is necessary to increase (AP). This paper presents our experience with 24 patients subjected to total correction of (tetralogía de Fallot) from March of 1975 to the present using the above criteria. The average age was 7 years (ranging from 2 to 20). In all cases the (cresta supraventricular) was (resected). In 14 (58%) a (valvultomia pulmonar) was performed and in 9 patients (37) it was necessary to increase the ring and pulmonary branch of the pulmonary artery according to measurements taken. The post-operative relationship PVD/PVI was 0.2-0.3: 15%, 0.4-0.5: 60%, 0.6-0.7: 25% In no case was the ratio greater than 0.70. No significant difference was found between those cases requiring... (parche transanular) and those where such treatment was not necessary. Three patients (12%) died immediately following the operation. It is concluded that measurement of the diameter of the pulmonary ring in comparison to the (superficie corporal) is extremely useful in management during surgery of (estenosis pulmonar) in patients with (tetralogía de Fallot).

Humans↗

[Corrected transposition of the great arteries in patients over 65].

Three cases with corrected transposition of the great arteries in patients older than 65 years are described. Two had atrial situs solitus and one atrial situs inversus. One had pulmonary valvular stenosis with valvular calcification and a small ventricular septal defect in association with ischemic heart disease. This patient died due to cardiac failure at the age of 80 years. The second case was associated with ventricular septal defect, atrial septal defect and pulmonary hypertension. The third patient presented with mild tricuspid regurgitation. Although this congenital heart malformation is theoretically compatible with normal life, few patients have long survival because of associated congenital defects or the subsequent development of tricuspid regurgitation or atrioventricular block.

Aged↗

[The transcatheter closure of patent ductus arteriosus. The initial experience].

Percutaneous closure of the patent ductus arteriosus (PDA) has been recently reported to be an effective alternative in the treatment of patients with ductal shunting. We report the initial experience and results during follow-up of percutaneous ductal occlusion with the Rashkind occluder (USCI) in six patients with isolated PDA. Ages ranged from 3 to 23 years. Diagnosis was corroborated with two dimensional and Doppler echocardiography in all patients. During cardiac catheterization systolic pulmonary artery pressure oscillated between 22 and 64 mmHg and Qp/Qs ratio between 1.3 and 4.1. In two patients prosthesis of 12 mm were used and in the remaining prosthesis of 17 mm. Only one patient demonstrated total occlusion during immediate control aortography, the other patients presented central residual shunting over the occluder. In the three patients occlusion with balloon-catheter was added to the procedure, resulting in total occlusion in two and significant reduction of the shunt magnitude in one. Two technical problems were resolved satisfactorily. None of the cases presented device embolization. Mean follow-up was 23.8 months with control echocardiograms at 24 hours, 1, 4, 12 and 24 months. In all patients immediate reduction of the left atrial dimension was demonstrated. Three patients presented residual shunts in the first 24 hours. In two of them total occlusion had occurred after one month and the other patient persisted with a small residual shunt until one year after the procedure. In conclusion, in this small study group good results were obtained with percutaneous ductal closure.

Adult↗

[Truncus arteriosus communis and interrupted aortic arch].

The association between persistent truncus arteriosus and interrupted aortic arch is a rare but important condition since it has special clinical and therapeutic implications. In this article we present three cases with this malformation. The clinical characteristics are similar to patients with isolated truncus such as heart failure and cyanosis since birth, a protosystolic click, an ejection murmur over the left parasternal line, heart enlargement, increased pulmonary vascular markings and biventricular hypertrophy. The clinical suspicion of interrupted aortic arch is bases on the presence of asymmetric pulses in the upper and lower limbs, but this difference is present only when the arterial duct is restrictive. Because of that, the echocardiographic analysis, mainly, and the angiocardiogram, secondarily, are very important diagnostic tools. We analyze the echocardiographic diagnostic findings, as well as the angiocardiographic anatomy. Also, some important pathophysiological aspects are discussed.

Aorta, Thoracic↗

[Pulmonary balloon valvulotomy. The results in 42 cases].

The percutaneous balloon valvulotomy is nowadays the treatment of choice for isolated pulmonary stenosis. Forty two patients with congenital pulmonary stenosis underwent balloon valvulotomy at the Instituto Nacional de Cardiología "Ignacio Chávez". Ages 1 month to 24 years, mean 7.6 +/- 5.9 years, with a follow-up of 28.3 +/- 14.8 months. With an infundibular gradient of 50 mm Hg or more a treatment with propranolol was given. After valvulotomy the total basal pressure gradient decrease from 82.9 +/- 40.6 mm Hg to 31.2 +/- 27.1 mm Hg (p < 0.00001). The patient's results were divided in two groups: with and without reactive infundibular obstruction. The 31 patients without infundibular obstruction had a total initial gradient of 71.6 +/- 33.5 mm Hg, and after valvulotomy the gradient was reduced to 18.9 +/- 11.2 mm Hg (p < 0.00001). The 11 patients with infundibular obstruction had a total initial gradient of 114.8 +/- 43.2 mm Hg, and after valvulotomy the valvular gradient was 12.4 +/- 8.5, the infundibular gradient 53.4 +/- 22.9 and the total gradient 65.9 +/- 29.1 mm Hg (p = 0.002 in relation to the basal gradient). All patients with infundibular obstruction (8 treated with Propranolol) and a follow-up of 8.5 +/- 9.8 months underwent Doppler examination, showing a progressive reduction of the total gradient. By six months no one had a total gradient greater than 50 mm Hg. These data confirm that balloon valvulotomy in valvular pulmonary stenosis is safe and effective, and that restenosis is very low. Good results relay on the use of proper balloon diameters (balloon diameter/pulmonary annulus relation of 1.2 to 1.5).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

[The termination of auricular flutter by noninvasive programmed electrical stimulation using a permanent AAI-mode pacemaker].

We describe a case of a 15-year-old boy with an atrial septal defect who three years after the direct closure of the defect presented with atrial flutter type I according to Wells's classification. He was then electrically cardioverted but presented immediately sinus bradycardia and a ventricular escape rhythm that required epicardial pacing (Intermedics 292-03 DASH) in the AAI mode. We report here the successful termination of a new episode of atrial flutter into sinus rhythm with a noninvasive programmed stimulation using his previously implanted pacing system.

Adolescent↗