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Biomedical subjects

F Aragona

Publications and source records attributed to F Aragona.

At least 163 records · Page 9Linked to original sources
PubMedDate not supplied

[Myelolipoma of the adrenal gland].

Adrenal myelolipomas are rare, nonfunctioning, benign neoplasms of the adrenal gland. The authors describe their experience of a case and they report the review of the literature. They illustrate what's etiopathogenetic theories, modern diagnostic technology "of imaging" and different surgical approaches need to be adapted to the excision of the adrenal myelolipomas.

Adrenal Gland Neoplasms↗
PubMedDate not supplied

[Pheochromocytoma and catecholamine cardiomyopathy].

We describe a 40 years old patient deceased of pheochromocytoma-caused heart failure, with no previous specific symptomatology. At autopsy the heart was characterised by thin cardiac walls and cavity dilatation. Histologic pattern showed extensive myocardial fibrosis and some acute myocytolytic areas. This pattern is equal to that of prolonged and decompensated stress cardiomyopathy. These pathologic pictures are both caused by catecholamines cardiotoxicity.

Adrenal Gland Neoplasms↗
PubMedDate not supplied

Lymph node metastases displaying lower Ki-67 immunostaining activity than the primary breast cancer.

UNLABELLED: The aim of the study was to verify by Ki-67 immunostaining if any difference exists in the cell proliferating fraction between primary breast tumors (PTs) and matching positive axillary lymph nodes (ALNs). PATIENTS AND METHODS: Immunohistochemistry with the monoclonal antibody against Ki-67 was performed in 160 node-positive breast carcinomas and in their respective lymph node metastases. RESULTS: An increase of Ki-67 immunoreactive cells in ALN compared with that of PTs was observed in 84% of cases (ALN: mean 17%, PTs: mean 8%; p < 0.001), whereas 16% of the cases showed Ki-67 value two to six times lower in the ALNs than in the corresponding PTs (ALN: mean 3.2%, PTs mean 12.5%; p < 0.005). The decrease of Ki-67 positive cells in the ALN was independent from the histotype and the histological grade of the tumor. CONCLUSION: A different cell proliferation fraction between PTs and matching positive ALNs was demonstrated and underlined that the existence of a group of patients with decreased number of Ki-67 immunoreactive cells in lymph node metastases compared with that of the primary tumors could be taken into account in the choice of therapeutic strategy.

Breast Neoplasms↗
PubMedDate not supplied

[Coagulative myocytolysis and its outcome in homicide victims. Reflexions on its relative psychologic meaning].

This research has been justified by the recent acquisitions about the pathogenic role that stress may play on myocardium, not only through the involvement of coronary vessels, but even through an action directed on the muscle fibres, which results in a coagulative myocytolysis with consequent fibrosis. The Author intended to verify the incidence of the above said cardiopathy, evaluating it with respect to the suprarenal glands changes, in the victims for homicide, mostly belonging to the criminal subculture of the province of Reggio Calabria. The choice of such a casuitic is based on the fact that the suprarenal glands study, carried out by the same Author on the above said victims since 1958 till today, has allowed to point out, excluding the cases of people accidentally involved in the crime (the so-called "innocent victims", typical morphological changes including all degrees of stress (acute, subacute or chronic), with the prevalence of those typical changes occurring in subacute or chronic forms, chiefly in the medullar gland. The research was carried out on the casuistic from two periods: 1st group: 1958-1975 (61 cases, 53 males, aged 10 to 73, mostly killed with fire-arms); 2nd group: November 1989-October 1990 (52 cases, almost exclusively males, aged 17 to 66, 51 of which killed with fire-arms, and one with a knife). The results are the following: 1) In the first group: a) 32 cases showed the presence of myocardial fibrosis striae, for the most part very thin, wavy and parallel to the myocytes; b) all the cases showed a hypercontracted aspect of the myocytes; c) 10 cases, belonging to the 32 cases with fibrosis, showed signs of acute myocytolysis; d) 13 cases showed mild signs of intimal fibrosis in the coronary arteries; e) 48 cases showed signs of subacute or chronic functional hyperactivity of the suprarenal glands, either in the medullar or in the cortical gland, often with signs of acute superstimulation; f) 12 cases showed exclusively signs of acute stimulation of the same glands; g) one case (innocent victim), showed suprarenal glands of normal aspect.(ABSTRACT TRUNCATED AT 400 WORDS)

Adolescent↗
PubMedDate not supplied

[Peripheral neuropathy during ocular myopathy: description of a case].

A case of ocular myopathy view presents only slight subjective symptoms, but a wide range of objective manifestations. The clinical features, but above all the morphological aspects of the muscle and the peripheral nerve presented by the patient, are briefly discussed, also in view of possible pathogenetic correlations.

Adult↗
PubMedDate not supplied

Computerized interactive morphometry as a potentially useful tool for the study of human placenta.

Two hundred human term placentas underwent morphometric study by means of semiautomated computerized method. Outer villous perimeter per cent parenchymal area and mean chord length were the investigated parameters. The mean value of outer villous perimeter, mean chord length and per cent area were respectively 46.9 mu (X 1000 mu 2) with a standard deviation of 4.6, 57.7 mu (standard deviation 9.3) and 66.1% (standard deviation 7.4). The relative distribution of these various parameters can constitute a valid basis for a comparison in cases of placental insufficiency.

Female↗