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Biomedical subjects

F A Jenner

Publications and source records attributed to F A Jenner.

At least 19 recordsLinked to original sources
PubMed1989

Castilla del Pino's contribution to a scientific psychopathology.

This paper attempts to express critically the basic concepts in the extensive writings on psychopathology of the Spanish author, Castilla del Pino. These are otherwise only available to the world in Castilian. His work offers a way in which the course and depth of psychotic disorders could be charted mathematically. It illustrates the fact that, what is apparently objective is still necessarily so within the confines of the conventions of our languages, from which we cannot ever escape. He nevertheless shows how psychopathology is not therefore fundamentally different from other sciences, even if its development remains rudimentary.

History, 20th Century↗
PubMed1989

Patterns of benzodiazepine use in Great Britain as measured by a general population survey.

In a general population survey by Gallup in Great Britain of 4148 subjects, 7.7% had taken benzodiazepines within the last year (male:female ratio 106:212). Younger subjects tended to take anxiolytics for shorter periods compared with older subjects, who often took hypnotics chronically. This pattern was most marked among females. Dosage escalation, tolerance, high daily dose usage, and hoarding were not common. A substantial proportion of current users had experienced difficulty in stopping their medication. Withdrawal problems were associated with being older than 45 years and consuming benzodiazepines for over 12 months. This lends support to the idea of benzodiazepine dependency. However, the appropriateness of long-term therapy for chronic symptoms cannot be ruled out.

Adolescent↗
PubMed1988

Literature on methadone maintenance clinics.

The literature on the impact of methadone maintenance clinics is presented and it is pointed out that only a very tentative evaluation can be made. The authors themselves, however, are opposed to these clinics based on the balance of the evidence available.

Heroin Dependence↗
PubMed1979

Urinary dicarboxylic acids in patients receiving lithium or rubidium salts.

Lithium salts administered in therapeutic doses to four subjects who were kept on controlled diets increased up to fivefold the urinary output of some dicarboxylic acids. Some of the acids affected are intermediates in the tricarboxylic acid cycle, others are chemically similar but not directly related in metabolic terms. This is probably a direct effect on renal transport. Rubidium salts increased urinary 2-oxoglutarate output and blood 2-oxoglutarate levels, probably by some action on intermediary metabolism.

Bipolar Disorder↗
PubMed1978

Nerve fibre refractory period in patients treated with rubidium and lithium.

Nerve fibre refractory period distributions have been measured on the median nerves of six manic-depressive patients controlled with lithium carbonate, three chronic patients (two manic-depressives and one catatonic schizophrenic) controlled with rubidium chloride, and eight normal volunteers. Rubidium prolonged the refractory periods of all nerve fibres while lithium increased only the longer refractory periods.

Adult↗
PubMed1978

Effects of rubidium chloride on the course of manic-depressive illness.

Clinical studies of the effects of rubidium ions on the course of manic-depressive illness are reported. It seems that rubidium tends to increase the length of manic phases and possibly reduces the extremes of mood. Rubidium did not seem to produce any severe side effects in the dose administered, but it has a long biological half-life and caution is still required. Some details of the CSF, RBC, saliva and plasma and urine kinetics are also reported.

Adult↗
PubMed1978

[Lord Adrian].

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History, 20th Century↗