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Biomedical subjects

F A Cioffi

Publications and source records attributed to F A Cioffi.

54 records · Page 3Linked to original sources
PubMedDate not supplied

Kinking and coiling of the internal carotid artery: Clinical-statistical observations and surgical perspectives.

The incidence of kinking and coiling of the internal carotid artery in an unselected series of 1,010 angiographies is reported. The angiographies of patients with cerebrovascular insufficiency and those of patients with other brain diseases were separately reviewed. On the basis of a statistical comparison, the finding of kinks and coils appears significantly higher in "vascular" than in "non-vascular" patients. The greater difference concerns age subgroups up to 50 years. These data give support to the assumption that both kinking and coiling of the internal carotid artery may play a role in determining cerebral ischemic attacks. Surgical experience concerns a series of 19 patients operated by various corrective procedures, including resection of the internal carotid artery and end-to-end anastomosis. It is felt that surgery, performed in appropriately selected cases, can afford significant benefits to cerebrovascular patients, especially those presenting recurrent ischemic episodes.

Adult↗
PubMedDate not supplied

Small arterial anastomoses: experimental models applicable to microneurosurgical practice.

Four main models of vascular microsurgical anastomoses in rabbits are described with reference to revascularization procedures in man. Some technical expedients designed to improve the patency rate, are outlined. This preliminary report emphasizes the value of laboratory training to achieve successful results with microneurosurgical treatment of cerebral ischemia.

Animals↗
PubMedDate not supplied

Cavernous angioma does not exist?

12 cases of cerebral "venous angioma" are reported; pathological, clinical and radiological features of the lesion are reviewed. "Venous angioma" should be regarded as a developmental anatomic variation of the venous drainage system of the white matter. Its clinical significance is controversial, although it has been reported to cause hemorrhage, seizures, progressive neurological deficits, headaches. The clinical presentation of our patients was variable and, in some of them, dependent also on associated lesions. An hematoma was found in three patients, infarction in one and tumor in one. Angiography, CT and MRI demonstrated the typical appearance of the anomaly. Surgery was performed in one patient harboring a significant cerebellar hematoma and the coexistence of a cavernoma was pathologically confirmed. Venous developmental anomalies are often identified as the source of symptoms due to other conditions, that should be treated independently sparing the anomaly.

Adult↗
PubMedDate not supplied

Spinal ossifying arachnoiditis. Case report.

A case of low dorsal spinal cord compression, due to ossifying arachnoiditis, is reported. Its relationship with a venous malformation overlying the dorsal surface of the spinal cord is mentioned. The literature is reviewed and possible etiopathogenetic factors favouring this rare condition are discussed in the light of few similar reports. The value of surgical treatment is stressed.

Arachnoiditis↗
PubMedDate not supplied

Cerebral pan-angiography in rabbit. Technical note.

An open technique of cerebral four-vessel angiography via femoral artery "in vivo" of the rabbit is described. This method allows a good visualization of extracranial and intracranial circulation without direct damage to the cerebral vessels.

Animals↗
PubMedDate not supplied

Ceftazidime in the treatment of infective complications of spinal cord lesions.

The use and the abuse of the antibiotics are certainly a subject of great concern, particularly for the increasing incidence of multiresistant bacteria. Since these resistant organisms may be sensitive to cephalosporin, we have tested the effectiveness of a new cephalosporin, ceftazidime, in the treatment of resistant infection in spinal cord injured patients. A randomized study of ceftazidime versus amikacin was carried out on twenty patients. The preliminary results are presented.

Adolescent↗
PubMedDate not supplied

Valuation of some biological parameters in acute spinal cord trauma: experimental study in rabbits.

The authors investigated the formation of edema consequent to Spinal Cord Injury in rabbits. The goal of this project was to study the accumulation of Water, Sodium, Potassium and Ferrum in traumatized cords in the early time after the acute injury. To this aim a spinal cord trauma was induced in forty unselected animals using the weight-drop method; Water content was measured by wet and dry weight method; Sodium, Potassium and Ferrum content were measured by atomic absorbance spectrophotometry. These parameters were recorded at various time from the cord trauma (30 minutes up to 14 days). The results are presented and discussed with a particular view to the relationships between biological variation and time from the injury.

Animals↗