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Biomedical subjects

F A Berry

Publications and source records attributed to F A Berry.

At least 37 records · Page 2Linked to original sources
PubMed1980

Transcutaneous oxygen monitoring of neonates during surgery.

Thirteen neonates who underwent surgery under general anesthesia were studied for a cumulative total of 30 hr of intraoperative transcutaneous oxygen (tcO2) monitoring. Simultaneous umbilical or radial arterial blood gas measurements were recorded frequently throughout each operation. A variety of drugs and anesthetics (including halothane) were used during surgery. PaO2 ranged from 27 to 390 mm Hg and PaCO2 ranged from 11 to 75 mm Hg. All patients but one required adjustment of inspired oxygen to correct abnormal values. In 11 of 13 patients there was close correspondence between PaO2 and PtcO2 (r = .92) in the absence of hypotension. In one patient, the transcutaneous electrode came loose, in another patient with edema the tcO2 monitor was unreliable both during and after surgery (r = .25). A low PtcO2/PaO2 ratio (.48) in one patient suggested decreased blood volume, and the ratio returned to normal (1.0) after a blood transfusion. The tcO2 monitor was the earliest indicator of airway compromise (extubation and kinked endotracheal tube) in two patients. The tcO2 monitor was reliable with inspired halothane of 1% or less. Since intraoperative blood gases fluctuate greatly and because of the risks of hypoxia and retrolental fibroplasia, it is important that frequent blood gas monitoring be routinely performed during neonatal surgery. In the non-edematous, normotensive patient, the tcO2 monitor is reliable and can provide an early indicator of intraoperative airway compromise, hypovolemia, hypoxemia, or hyperoxemia.

Humans↗
PubMed1975

Lidocaine and its metabolites in the newborn.

Concentrations of lidocaine and its metabolites were measured chromatographically in the blood and urine of mothers and babies after epidural administration of lidocaine to the mother for cesarean delivery. Delivery occurred a mean time of 29.83 plus or minus 8.64 minutes after a mean dose of 398.33 plus or minus 63.38 mg to the mother, at which time mean maternal venous plasma concentration was 1.70 plus or minus 0.77 mug/ml. Of the total molar quantity of lidocaine and metabolite recovered from the newborns' urine in the first 12 hours of life, 50.63 per cent appeared as unchanged lidocaine, while 49.37 per cent appeared as metabolites. In the second 12 hours of life, 23.37 per cent appeared as unchanged lidocaine, while 76.63 per cent appeared as metabolites. We conclude that the greater proportion of metabolite excretion in the second 12 hours is evidence that the new born is capable of metabolizing lidocaine.

Anesthesia, Epidural↗
PubMed1975

New surgical concepts resulting from cranio-orbito-facial surgery.

The authors have defined the subspecialty of craniofacial surgery and described the organization of the multi-disciplinary team required to care for such patients. Common features of the craniofacial patient have been summarized and three major categories of patients have been proposed. These are: I. Syndromes associated with hypertelorism; II. Syndromes associated with premature synostoses or growth arrests; III. Syndromes associated with primarily mid- and lower face anomalies. Growing out of an experience with 242 operations on 106 patients, the authors have listed 9 relatively new surgical "principles." Each has led to a current surgical approach that is now being employed by the craniofacial team at The University of Virginia. A number of examples are given to show ways in which the lessons learned from the craniofacial patients are now being applied, with improved results, to patients with neoplasms, traumatic injuries, or other conditions.

Anesthesia, General↗