Biomedical subjects

Eric Soetens

Publications and source records attributed to Eric Soetens.

12 recordsLinked to original sources

PubMed2006

Learning sequence movements in a homogenous sample of patients with Parkinson's disease.

We investigated the acquisition of sequence movements in Parkinson's disease (PD) by means of the serial reaction time (SRT) task. To this end, we used a sample of PD patients that fell within the same stage of the disease. Sixteen PD patients and 16 age-, sex- and education-matched control subjects performed the SRT task with a first-order conditional (FOC) sequence and with a second-order conditional (SOC) sequence. The results showed that the group of PD patients could be divided into two distinct subgroups: a fast PD patient subgroup (n=11) and a slow PD patient subgroup (n=5). FOC and SOC sequence learning in faster PD patients proved to be highly comparable to the group of controls. In contrast, learning of FOC and SOC sequences was severely impaired in slower PD patients. Since slow PD patients also scored lower on measures of cognitive functioning than faster PD patients, we assume that the deficits in SRT learning of the former reflect some more general cognitive impairment. This indicates that SRT performance can provide additional information about the cognitive abilities of PD patients, and accordingly may contribute to disease screening.

Aged↗

PubMed2006

Spatial processing and perceptual sequence learning in SRT tasks.

We investigated the influence of processing relevant spatial information on learning a probabilistic sequence of irrelevant locations. Using the SRT design of Remillard (2003), we found that spatial perceptual learning occurs with paired but not with single targets. The pairs of targets consisted of the same stimuli, but in a different order, so that responses could have been based on the left-right location of an element, relative to the other element of the pair. The prerequisite of spatial pairs of targets suggests that spatial processing of relevant information plays a crucial role in perceptual location learning. In addition, spatial perceptual learning only took place when the target pair was presented together with other stimuli, but was absent when the target pair was presented in a blank field. Since in the latter case attention is automatically captured, this suggests that sequence learning requires endogenous attention.

Adult↗

PubMed2006

Sustained suppression in congruency tasks.

In a list version of the Stroop task, Thomas observed that Stroop interference was smaller when the irrelevant word was repeated through parts of the list. MacLeod formulated the sustained-suppression hypothesis for this effect. It is assumed that the automatic response activation on the basis of the irrelevant word is selectively suppressed. In this paper this hypothesis is further investigated. In a serial Stroop task with short response-stimulus interval (RSI) we demonstrate that the Stroop effect disappears when the irrelevant word is repeated, whereas the Stroop effect is evident when the word changes. With a long RSI, there is no influence of the sequence of the irrelevant word. The same pattern of results is observed in a flanker task. The results are discussed in terms of the activation-suppression model (Ridderinkhof) and the sustained-suppression hypothesis.

Adolescent↗

PubMed2006

The role of response selection in sequence learning.

We investigated the role of response selection in sequence learning in the serial reaction time (SRT) task, by manipulating stimulus-response compatibility. Under conditions in which other types of learning, like perceptual, response-based, and response-effect learning, were unaffected, sequence learning was better with an incompatible than with a compatible stimulus-response mapping. Stimulus discriminability, on the other hand, had no influence on the amount of sequence learning. This indicates that the compatibility effects cannot be accounted for by a different level of task difficulty. Relating our results to the dimensional overlap model (Kornblum, Hasbroucq, & Osman, 1990), which assumes that incompatible stimulus-response mappings require more controlled response selection than do compatible stimulus-response mapping, we suggest that sequence learning in the SRT task is particularly effective when response selection occurs in a controlled way.

Adult↗

PubMed2005

Effector-dependent and response location learning of probabilistic sequences in serial reaction time tasks.

We investigated the contributions of the sequences of effectors and response locations to probabilistic sequence learning in the serial reaction time task by means of bimanual transfer. Participants, trained with the dominant hand, were either required to maintain responding with the dominant hand after transfer or to switch to the nondominant hand. For both groups, half of the participants were transferred to the originally trained sequence, whereas the other half was transferred to a mirror-ordered sequence. This way, the sequence of effectors varied independently of the sequence of response locations. Sequence learning was assessed with probabilistic sequences, composed of either first-order or second-order probabilities. Transfer of sequence knowledge to the nondominant hand was equally good for the originally trained sequence as for the mirrored sequence. This suggests that probabilistic sequence learning can be based on either the sequence of effectors or response locations. However, when participants responded with the dominant hand to a mirrored sequence, transfer performance was disturbed. This indicates that changing both the sequences of effectors and response locations has a disruptive effect on the learning performance.

Adult↗

PubMed2005

Response monitoring and expectancy in random serial RT tasks.

Two different sequential patterns have been reported in serial reaction-time (RT) tasks with random stimulus sequences, depending on the response-to-stimulus interval (RSI). When RSI is short a first-order repetition effect and a higher order benefit-only pattern are found, and when RSI is long a cost-benefit pattern is observed. In a series of three experiments, we found that the patterns are not unique for spatial dimensions, and that the benefit-only pattern does not appear for irrelevant stimulus features. The cost-benefit pattern, on the other hand, can shift to irrelevant locations, but not to irrelevant colour. Distributional analyses of the sequential effects demonstrate that the first-order repetition effect can be dissociated from the higher order effects. The results are interpreted as support for the role of response monitoring in the development of the benefit-only pattern at short RSI, while the first-order repetition effect is explained as repetition priming. With a long RSI, the cost-benefit pattern is confirmed as a low-level subjective expectancy process, which is primarily controlled by stimulus location. The data clearly strengthen the support for three different processes generating sequential effects in random serial RT tasks.

Adult↗

PubMed2004

Perceptual or motor learning in SRT tasks with complex sequence structures.

We investigated under which conditions sequence learning in a serial reaction time task can be based on perceptual learning. A replication of the study of Mayr (1996) confirmed perceptual and motor learning when sequences were learned concurrently. However, between-participants manipulations of the motor and perceptual sequences only supported motor learning in cases of more complex deterministic and probabilistic sequence structures. Perceptual learning using a between-participants design could only be established with a simple deterministic sequence structure. The results seem to imply that perceptual learning can be facilitated by a concurrently learned motor sequence. Possibly, concurrent learning releases necessary attentional resources or induces a structured learning condition under which perceptual learning can take place. Alternatively, the underlying mechanism may rely on binding between the perceptual and motor sequences.

Adult↗

PubMed2004

Sequential effects on speeded information processing: a developmental study.

Two experiments were performed to assess age-related changes in sequential effects on choice reaction time (RT). Sequential effects portray the influence of previous trials on the RT to the current stimulus. In Experiment 1, three age groups (7-9, 10-12, and 18-25 years) performed a spatially compatible choice task, with response-to-stimulus intervals (RSIs) of 50 and 500 ms varied between trial blocks. In Experiment 2, three age groups (7-9, 15-16, and 18-25 years) performed the task with spatial stimulus-response (S-R) mappings (compatible versus incompatible) varied between participants. For adults, the experiments yielded a pattern of sequential effects suggestive of "automatic facilitation" (i.e., a first-order repetition effect and a higher order benefit-only pattern for short RSIs) and "subjective expectancy" (i.e., a first-order alternation effect and a higher order cost-benefit pattern for long RSIs). Automatic facilitation was more pronounced for incompatible responses than for compatible responses. Both experiments showed the anticipated decrease in automatic facilitation with advancing age. Finally, the first-order alternation effect showed the predicted age-related increase, but the cost-benefit pattern revealed an opposite trend, suggesting that the first-order and higher order indexes of subjective expectancy may relate to dissociable mechanisms.

Adolescent↗

PubMed2003

Irrelevant auditory attention shifts prime corresponding responses.

In this paper we investigate whether an attention shift towards an auditory signal, while performing a two-choice serial reaction time task, primes responses in the direction of the auditory signal. In Experiment 1, subjects had to react to the pitch of the signal, which was randomly presented to the left or right ear. A short (50-ms) and a long (1000-ms) response-stimulus interval (RSI) was used. In Experiment 2 with an RSI of 2000 ms, subjects had to respond to the color of a centrally presented visual stimulus, while a sound was presented to one of the ears. In the short RSI condition of Experiment 1, there was a Simon effect for location alternations only. In the long RSI condition, there was a Simon effect for location repetitions and alternations. Experiment 2 showed a Simon effect in relation to the accessory sound. The results of this study suggest that an attention shift is a sufficient and necessary condition in order to observe a Simon effect.

Adolescent↗

PubMed2003

The influence of irrelevant stimulus changes on stimulus and response repetition effects.

In this study the influence of irrelevant stimulus changes from one trial to another in a serial reaction time task was investigated. Two experiments were performed in which subjects were required to respond to stimulus colour. Four colours were mapped on two response keys, so that colour and response repetition effects could be dissociated. In Experiment 1, the irrelevant stimulus dimension was location and in Experiment 2 it was shape. Both experiments were performed with a short and a long response-stimulus interval (RSI)-condition. In both experiments, the irrelevant dimension influenced the response repetition effect but not the colour repetition effect. In the reaction times, a response alternation effect was observed only when the irrelevant location of the stimulus changed in the long RSI-condition. The error rates showed a response alternation benefit for both irrelevant dimensions, in the short and the long RSI-condition. The benefit for response alternations is explained in terms of a response bias towards change that is triggered by a changing stimulus feature. We assume that the response bias is stronger for location than for colour and that accuracy is more sensitive to this bias than response latencies.

Adolescent↗

PubMed2002

Process-specific slowing with advancing age: evidence derived from the analysis of sequential effects.

In the current study we examined the generalized slowing hypothesis on the mechanisms underlying sequential effects in serial two-choice reaction time tasks. For young adults, sequential effects of conditions with a high and a low stimulus presentation rate respectively pointed to an automatic and an expectancy mechanism. Older adults' low presentation rate data corroborated the general slowing hypothesis for expectancy, whereas the high presentation rate results did not. The observation of a differential influence of age on the automatic and the expectancy mechanism poses a problem for notions assuming that higher level processes are more vulnerable to advancing age than lower level processes.

Adult↗

PubMed2002

Control over location-based response activation in the Simon task: behavioral and electrophysiological evidence.

In 4 Simon experiments the authors examined control over 2 routes of sensorimotor processing: response priming in the unconditional route and response selection via the conditional route. The Simon effect diminished as the frequency of noncorresponding trials increased. Location-based response priming was observed only when the stimulus followed a corresponding event but not after a noncorresponding trial. Therefore, the unconditional route appears to be suppressed whenever the task context indicates priming as potentially disadvantageous. Moreover, the task-irrelevant stimulus location was used for response selection as a function of correspondence probability. Although exact repetitions of stimulus-response sequences caused a marked speed-up of responses, this 3rd mechanism is independent of unconditional route suppression and frequency-based adjustments in the conditional route.

Adult↗