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Elliot K Fishman

Publications and source records attributed to Elliot K Fishman.

At least 91 records · Page 5Linked to original sources

Multidetector CT angiography for preoperative evaluation of living laparoscopic kidney donors.

OBJECTIVE: The purpose of this study was to determine the accuracy of multidetector CT (MDCT) angiography as the primary imaging technique in the evaluation of living kidney donors. SUBJECTS AND METHODS: Seventy-four consecutive living kidney donors (30 men, 44 women; mean age, 41.7 years) who underwent MDCT were evaluated. CT examination was performed with 120 mL of IV contrast material at an injection rate of 3 mL/sec and a pitch of 6. In every case, arterial and venous phase volumetric data sets were acquired at 25 and 55 sec, respectively. Scans were reconstructed at 1-mm intervals for three-dimensional (3D) imaging using a volume-rendering technique. Axial CT images and 3D CT angiography were evaluated prospectively by one reviewer and retrospectively by two reviewers who had no knowledge of surgical results. Surgical correlation for the location of primary and accessory renal arteries, early branching of the renal arteries, and renal vein anomalies was made. RESULTS: Seventy-two subjects underwent left nephrectomy, and two subjects underwent right nephrectomy because supernumerary left renal arteries were detected on preoperative CT angiography. Eighteen supernumerary renal arteries (two arteries to 16 kidneys and three arteries to one kidney) to 74 kidneys underwent nephrectomy. CT and surgical findings agreed in 93% of subjects (the average of three reviewers; range, 89-97%). Two small accessory renal arteries were missed by all three reviewers. Those arteries were diminutive and were thought to be insignificant by the surgeons. Early branching of the renal arteries was shown in 14 arteries, and CT and surgical findings agreed in 96% (the average of three reviewers; range, 93-97%). Renal vein anomalies were present in eight subjects, and CT and surgical findings agreed in 99% of the cases (range, 96-100%). CONCLUSION: MDCT angiography is highly accurate for detecting vascular anomalies and providing anatomic information for laparoscopic living donor nephrectomy.

Adult↗

Sacral fractures: a potential pitfall of FDG positron emission tomography.

OBJECTIVE: Positron emission tomography (PET) with FDG is useful for tumor imaging, but false-positive results can occur. The purpose of this study is to describe three oncology patients with sacral fractures in whom FDG uptake in the sacrum increased on PET. CONCLUSION: Sacral fractures can show increased uptake of FDG on PET. Therefore, correlative cross-sectional imaging is necessary to avoid the erroneous diagnosis of sacral metastases on PET and prevent inappropriate treatment of patients.

Aged↗

Initial experience with oral contrast in PET/CT: phantom and clinical studies.

UNLABELLED: The aims of the study were to evaluate the effects of oral contrast on apparent tracer activity measured with PET/CT when using CT attenuation correction and to report our initial experience in the use of oral contrast with PET/CT. METHODS: Phantom studies with (18)F activity and saline bags or syringes filled with barium or gastrografin of varying densities were performed using a PET/CT scanner (CT attenuation correction). In the study, 91 clinical patients received dilute oral contrast and were evaluated by whole-body (18)F-FDG PET. RESULTS: A phantom experiment with CT contrast (1.3% weight/volume [w/v] barium) showed a "cold" area in the cold stomach whereas a phantom with high-density barium (98% w/v) showed an artifactual focus of intense "activity" in the cold stomach. In clinical studies, stomach and right colon were opacified by CT contrast. Maximal measured contrast density was 239 Hounsfield units. CONCLUSION: High-density barium causes overestimation of tissue (18)F-FDG concentration. Low-density barium does not cause significant artifacts and appears suitable for clinical use.

Administration, Oral↗

Anterior mediastinal extension of primary chest wall infections: role of spiral CT in detection and management.

UNLABELLED: The purpose of this review was to define the role of spiral CT in the diagnosis and clinical management of patients with mediastinal infections resulting from extension of anterior chest wall infections. The review focuses on determining the frequency of mediastinal extension of chest wall infections as well as to define the patterns spread. SUBJECTS AND METHODS: CT scans of 22 consecutive patients collected over a 2-year period with anterior chest wall infections were evaluated both prospectively and retrospectively. Clinical, pathologic, and CT characteristics of the infections were evaluated. The extension of the infection into the mediastinum as well as the role of CT in diagnosis and management of these patients was examined. RESULTS: Of the 22 patients, 10/22 (45.4%) showed CT evidence of mediastinal infection. Extension of chest wall infection occurred in patients with both soft tissue and sternoclavicular joint processes. The assessment of mediastinal involvement was best seen at the level of the great vessels origin from the aortic arch. CT findings in the mediastinum included fat hyperdensity and stranding, fluid collections (abscess), and mass effect on the great vessels. Sensitivity and specificity of CT for determination of mediastinal infection were both 100%. In 5 of 10 cases with evidence of mediastinal extension, the clinical situation required surgical drainage. In the other five cases the patients were managed with antibiotic therapy alone. CONCLUSIONS: Mediastinal involvement of chest wall infections is a common occurrence. Conservative and/or surgical management must be tailored to the patient. Factors to consider in management decisions include the clinical status, CT findings, and patient compliance. Rapid CT evaluation may permit timely surgical intervention, limiting complications in some patients.

Adult↗

Abdominal involvement in tuberculosis.

Rising incidence of disseminated and extrapulmonary tuberculosis (TB), especially in immunocompromised hosts and patients with multi-drug-resistant tuberculosis, has resulted in an increase of unusual clinical and radiographic presentations of TB. With CT being a common part of emergency room (ER) evaluation of abdominal pain, it is imperative that radiologists be able to recognize abdominal presentations of TB. We discuss and illustrate typical and less common CT manifestations of tuberculosis in the abdomen to help ER radiologists in this task.

Journal Article↗

Prevalence of significant noncardiac findings on electron-beam computed tomography coronary artery calcium screening examinations.

BACKGROUND: Screening electron-beam computed tomography (EBCT) examinations for the detection and quantification of coronary artery calcification are being performed throughout the country. In addition to information about the heart, great vessels, and coronary arteries, these examinations include portions of the lungs, bony thorax, and upper abdomen. The purpose of this study was to determine the prevalence of significant noncardiac findings in a series of patients undergoing coronary artery calcification screening studies with EBCT scanning. METHODS AND RESULTS: Between January 1, 2001, and October 1, 2001, 1326 consecutive patients underwent coronary artery calcification screening with EBCT (3-mm-thick slices were obtained at 3-mm intervals). Two board-certified radiologists reviewed the examinations on a workstation using standard mediastinal windows, lung windows, and bone windows. Significant extracardiac abnormalities were noted. Of 1326 patients, 103 (7.8%) had significant extracardiac pathology requiring clinical or imaging follow-up. These included 53 patients with noncalcified lung nodules <1 cm, 12 patients with lung nodules > or =1 cm, 24 patients with infiltrates, 7 patients with indeterminate liver lesions, 2 patients with sclerotic bone lesions, 2 patients with breast abnormalities, 1 patient with polycystic liver disease, 1 patient with esophageal thickening, and 1 patient with ascites. CONCLUSIONS: In this study, 7.8% of patients undergoing screening EBCT examinations for coronary artery calcification were found to have important extracardiac pathology requiring additional work-up. Therefore, it is essential that a radiologist review the entire examination.

Adult↗

Positron emission tomography for detecting clinically occult surgically resectable metastatic ovarian cancer.

BACKGROUND: The specific indications for PET imaging in patients with ovarian cancer have yet to be precisely defined. While PET has limited sensitivity for detecting small-volume (<1 cm) metastatic disease, accurate identification of larger tumor nodules may have a significant impact on clinical management and the selection of patients for cytoreductive surgery. CASES: The cases of two patients with suspected recurrent Stage IIIC serous ovarian cancer based solely on elevated CA125 levels and one patient with an apparent Stage IC poorly differentiated ovarian sex cord-stromal tumor who had macroscopic surgically resectable disease (>1 cm) identified by PET after negative or equivocal computed tomography are presented. CONCLUSION: PET imaging may be a useful technique for identifying potentially surgically resectable, macroscopic metastatic ovarian cancer when computed tomography findings are negative or equivocal.

Adolescent↗

Imaging of uncommon tumors of the pancreas.

In this article, the radiological manifestations of a variety of uncommon tumors of the pancreas are illustrated, with emphasis placed on their appearance at helical CT. Islet cell tumors, because of their vascularity, typically present as masses that are hyperattenuating to the normal pancreas at dual-phase helical CT. Lymphomas appear as hypoattenuating focal lesions or can diffusely infiltrate the gland. Absence of biliary tree dilatation, despite the presence of a bulky tumor, or associated extensive retroperitoneal adenopathy should offer clues to the diagnosis. Pancreatic metastases are usually seen in patients with advanced cancers, although isolated metastases from renal cell carcinoma can occurs years after the original tumor; such patients may benefit from surgical resection. Finally, the appearance of some rare neoplasms of mesenchymal origin is discussed.

Adenoma, Islet Cell↗

Adenocarcinoma of the pancreas: CT imaging.

CT currently plays a vital role in pancreatic cancer staging. Continued advancements in computers, scanner technology, and 3D software have improved CT detection of smaller masses and staging. In particular, the introduction of MDCT and real-time 3D volume-rendering software have greatly improved the visualization of the pancreas and adjacent vasculature. This progress will continue as manufacturers introduce the next generation of scanners, which can acquire up to 32 slices per second with ever faster scan times. The impact of these new scanners on diagnostic accuracy will need to be carefully evaluated.

Adenocarcinoma↗

Classic bladder exstrophy in a nonhuman primate: a comparative analysis.

OBJECTIVES: To describe the pelvic floor musculature and bony pelvic anatomy in a case of naturally occurring classic bladder exstrophy in a rhesus monkey, the first reported case in the animal population since 1832, and compare the results to exstrophy seen in human newborns. METHODS: A 7-day-old male rhesus monkey with classic bladder exstrophy was examined by a pediatric urologist and primate veterinarian before being killed. A multidetector row computed tomography study with three-dimensional reconstruction was obtained, and a comparison computed tomography study of a 17-day-old male human with exstrophy was also reconstructed three dimensionally. The bony pelvis and pelvic floor muscular anatomy of both subjects were then examined and compared. RESULTS: On gross examination, a similar appearance of classic bladder exstrophy in the rhesus monkey and human newborn were noted, including an open exposed bladder, associated penile epispadias, and widely separated pubic bones. The evaluation of the three-dimensional models showed a similar orientation of the bony pelvis in both the rhesus and the human newborn. The iliac wings were significantly rotated outward, and the sacroiliac joint was 10 degrees wider than that seen in normal children. The exstrophy pelvic floor in both the rhesus and the newborn was markedly flattened, with approximately 33% of the muscle located anterior to the rectum to support the pelvic structures (normal children have 50% of their levator ani anterior to the rectum). CONCLUSIONS: By using advancements in imaging modalities, this study illustrated that naturally occurring classic bladder exstrophy in the human newborn and rhesus monkey were identical in both external appearance and internal anatomy.

Animals↗

Influence of a new prophylactic antibiotic therapy on the incidence of liver abscesses after chemoembolization treatment of liver tumors.

Intrahepatic abscess is a complication of transcatheter arterial chemoembolization (TACE) treatment in patients who have a history of biliary reconstructive surgery. This study followed eight patients who underwent chemoembolization after biliary surgery. These patients were divided into two groups. Patients in group one (n = 4) were administered intravenous cephalexin for prophylaxis. Patients in group two (n = 4) were administered bowel preparation and tazobactam/piperacillin. All patients in group one developed hepatic abscesses, which were treated with percutaneous catheter drainage and antibiotics. None of the patients in group two developed abscesses. Aggressive antibiotic prophylaxis with bowel preparation may provide protection against intrahepatic abscesses after chemoembolization in patients who have a history of biliary reconstructive surgery.

Adenocarcinoma↗

Availability, requesting practices, and barriers to referral for high-resolution CT of the lungs: results of a survey of U.S. pulmonologists.

RATIONALE AND OBJECTIVES: The authors performed this study to assess the availability of high-resolution computed tomography (CT), current referral practices, and potential barriers to the clinical use of high-resolution CT in patients with diffuse lung disease. MATERIALS AND METHODS: The authors sent a survey to 450 pulmonologists who were members of the American College of Chest Physicians. They sought information about the availability of high-resolution CT services, explored the physicians' current requesting practices and the monthly number of referrals, and assessed the influence of six factors on the decision to refer. RESULTS: The authors received completed surveys from 230 pulmonologists (52.6%). High-resolution CT services were available to all respondents and had been used by 226 (98.3%) of them during the preceding 12 months. Two-thirds of respondents referred one to four patients per month, and one-third referred five or more. Monthly referral volume did not significantly vary among different practice types. The pulmonologists expressed a preference for hospital-based imaging facilities and routinely reviewed the images from the examinations they ordered. The most frequent reason for high-resolution CT was classification of a known interstitial process. High-resolution CT was infrequently requested to evaluate symptomatic immunocompromised patients. Confidence in the radiologist's high-resolution CT interpretation was the most important factor influencing the referral decision, and radiation dose to the patient was the least important. CONCLUSION: High-resolution CT services are widely available to and frequently requested by U.S. pulmonologists in a variety of practice settings. High-resolution CT may be underutilized in symptomatic immunocompromised patients. Radiologists should be aware that the perception of their skill in high-resolution CT interpretation is an important determinant in the pulmonologist's decision to refer.

Adult↗