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Eldon R Smith

Publications and source records attributed to Eldon R Smith.

At least 19 recordsLinked to original sources

Ethics for editors.

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Editorial Policies↗

Opening the pericardium during pulmonary artery constriction improves cardiac function.

During acute pulmonary hypertension, both the pericardium and the right ventricle (RV) constrain left ventricular (LV) filling; therefore, pericardiotomy should improve LV function. LV, RV, and pericardial pressures and RV and LV dimensions and LV stroke volume (SV) were measured in six anesthetized dogs. The pericardium was closed, the chest was left open, and the lungs were held away from the heart. Data were collected at baseline, during pulmonary artery constriction (PAC), and after pericardiotomy with PAC maintained. PAC decreased SV by one-half. RV diameter increased, and septum-to-LV free wall diameter and LV area (our index of LV end-diastolic volume) decreased. Compared with during PAC, pericardiotomy increased LV area and SV increased 35%. LV and RV compliance (pressure-dimension relations) and LV contractility (stroke work-LV area relations) were unchanged. Although series interaction accounts for much of the decreased cardiac output during acute pulmonary hypertension, pericardial constraint and leftward septal shift are also important. Pericardiotomy can improve LV function in the absence of other sources of external constraint to LV filling.

Animals↗

The cost of illness.

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Biomedical Technology↗

Academic health sciences centres: a view from the academy.

Academic Health Sciences Centres have provided and continue to provide valuable service to society. However, the lack of a clear mandate, structure, governance and administration results in their full potential not being met. As the Canadian healthcare system undergoes the reform that must occur to make the publicly funded system sustainable into the future, it is essential that AHSCs have clarification of their roles, develop a distinct governance structure and be provided a distinct budget for a set of deliverables within an agreed-upon accountability framework.

Academic Medical Centers↗