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Biomedical subjects

Edward Onusko

Publications and source records attributed to Edward Onusko.

3 recordsLinked to original sources

Chest pain, weakness, and elevated cardiac enzymes: how would you treat?

You are making rounds in the hospital one Saturday morning when you receive a call from the emergency department saying a 68-year-old man is having chest pain, weakness, and "positive cardiac enzymes." His electrocardiogram (ECG) reading is reported as unremarkable. Because it is the weekend and no cardiology consultation is available at your hospital, the family medicine resident wants to know if you would like to admit the patient to your service or transfer him to a larger hospital. You decide that you can best make this decision by going to the emergency department and personally evaluating the patient.

Aged↗

Tympanometry.

Tympanometry provides useful quantitative information about the presence of fluid in the middle ear, mobility of the middle ear system, and ear canal volume. Its use has been recommended in conjunction with more qualitative information (e.g., history, appearance, and mobility of the tympanic membrane) in the evaluation of otitis media with effusion and to a lesser extent in acute otitis media. It also can provide useful information about the patency of tympanostomy tubes. Tympanometry is not reliable in infants younger than seven months because of the highly compliant ear canals of infants. Tympanogram tracings are classified as type A (normal), type B (flat, clearly abnormal), and type C (indicating a significantly negative pressure in the middle ear, possibly indicative of pathology). According to the Agency for Healthcare Research and Quality guidelines on otitis media with effusion, the positive predictive value of an abnormal (flat, type B) tympanogram is between 49 and 99 percent. A type C curve may be useful when correlated with other findings, but by itself it is an imprecise estimate of middle ear pressure and does not have high sensitivity or specificity for middle ear disorders.

Acoustic Impedance Tests↗

Diagnosing secondary hypertension.

Secondary hypertension is elevated blood pressure that results from an underlying, identifiable, often correctable cause. Only about 5 to 10 percent of hypertension cases are thought to result from secondary causes. The ABCDE mnemonic can be used to help determine a secondary cause of hypertension: Accuracy of diagnosis, obstructive sleep Apnea, Aldosteronism, presence of renal artery Bruits (suggesting renal artery stenosis), renal parenchymal disease (Bad kidneys), excess Catecholamines, Coarctation of the aorta, Cushing's syndrome, Drugs, Diet, excess Erythropoietin, and Endocrine disorders. An algorithm showing the general strategy to help screen for factors involved in secondary hypertension is presented. Routine urinalysis, complete blood cell count, blood chemistry profile (potassium, sodium, creatinine, fasting glucose, fasting lipid levels), and a 12-lead electrocardiogram are recommended for all patients with hypertension.

Blood Pressure Determination↗