Biomedical subjects

Edward Gardner

Publications and source records attributed to Edward Gardner.

4 recordsLinked to original sources

PubMed2004

Contrast-agent detection and quantification.

The Cadence contrast pulse sequencing (CPS) technology offers improved clinical information and workflow efficiency during contrast agent examinations. The technology harnesses unique non-linear microbubble energy discovered within the same fundamental frequency band as the transmitted pulses of sound and thus offers improved sensitivity and penetration. An auto tracking contrast quantification (ACQ) technology further complements the CPS detection technology with automatic image alignment during quantification with features such as on-line multiple time intensity curves (TIC). The regional image analysis holds promise of alleviating workflow inefficiency associated with manual alignment of image frames.

Contrast Media↗

PubMed2003

Stereotactic radiosurgery for patients with cancer of the head and neck.

Patients with recurrent cancer of the head and neck involving the base of the skull have limited treatment options. Stereotactic radiosurgery is currently being investigated as a viable modality of treatment for these patients. This paper reviews the basic principles and treatment procedures involved in stereotactic radiosurgery, as well as published reports on its use with these patients. Finally, questions to be addressed by future studies for clarification of the role of this technology are outlined.

Dose Fractionation, Radiation↗

PubMed2002

Tympanoplasty results in patients with cleft palate: an age- and procedure-matched comparison of preliminary results with patients without cleft palate.

OBJECTIVE: Because of continued eustachian tube abnormalities, the presence of a cleft palate repair has been thought to be associated with poor outcomes after tympanoplastic surgery. However, little published data exist regarding the results of major otologic surgery in patients with cleft palate. The objective of this study was to review our results of otologic surgery in these patients and compare results with those of age- and procedure-matched controls. METHODS: Our otologic database was used to identify patients with a repaired cleft palate who underwent otologic surgery between March 1994 and December 1999. Two control patients were identified for each cleft palate patient. Results of hearing, graft take, and need for postoperative pressure-equalizing tubes were compared. RESULTS: No significant difference existed between patients with a repaired cleft palate and control patients with regard to postoperative air-bone gap (P = 0.6805), graft survival rate (P = 1.00), and need for postoperative intubation (P = 0.457). CONCLUSION: Results in patients with cleft palate appear to be similar to those in patients without cleft palate.

Adolescent↗

PubMed2002

Hearing results with a hydroxylapatite/titanium bell partial ossicular replacement prosthesis.

OBJECTIVES/HYPOTHESIS: To study the preliminary hearing results in patients receiving a hybrid hydroxylapatite/titanium bell partial ossicular replacement prosthesis (PORP) and compare these with a cohort of patients receiving a HAPEX PORP. We hypothesized that the design of the hybrid PORP would enhance its acoustic properties. In particular, the titanium bell, which allows the prosthesis to be freestanding, would obviate the need for Gelfoam, preventing fibrosis. STUDY DESIGN: A retrospective study was made of two cohorts of patients. METHODS: A computerized otologic database was used to identify all patients implanted with either PORP. The four-frequency (500, 1000, 2000, and 3000 Hz) pure-tone average air-bone gap (PTA-ABG) and ABG values for individual frequencies were compared using the Student test. RESULTS: The PTA-ABG for the titanium bell prosthesis was 9.8 +/- 5.7 dB, compared with 13.2 +/- 8.3 dB for the HAPEX PORP, which was statistically significant ( P<.05). The average ABG values at 500 and 1000 Hz were also statistically significantly improved with the titanium bell PORP ( P<.05). CONCLUSIONS: The titanium bell PORP showed improved postoperative results for the PTA-ABG and at 500 Hz and 1000 Hz. The prosthesis is freestanding and may provide better coupling with the capitulum, factors which may lead to improved hearing results in the lower frequencies.

Adolescent↗