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E von der Lippe

Publications and source records attributed to E von der Lippe.

17 recordsLinked to original sources
PubMed2001

[Two cases of pneumococcal pericarditis].

BACKGROUND: Bacterial pericarditis is often overlooked, partly because symptoms and signs associated with pericarditis are frequently missing, but also because of the rarity of the disease. MATERIAL AND METHODS: Two cases of pneumococcal pericarditis treated at Ullevaal University Hospital are presented. RESULTS: Pneumococcal pericarditis is a rare, but serious complication to infections like pneumonia, pleural empyema, and septicaemia. Patients with an infectious disease who develop signs of elevated central venous pressure, enlarged cardiac silhouette on chest x-ray, or severe hypotension should have an echocardiography performed. If pericardial fluid is present, a diagnostic pericardiocentesis should be considered. INTERPRETATION: Treatment consists of drainage and antibiotics. Pericardiocentesis and subxiphoid catheter drains may be inadequate because of fibrin precipitation resulting in organization of the fluid. In these cases surgical intervention has traditionally been recommended, but intrapericardial fibrinolysis could be an alternative.

Aged↗
PubMed1998

[Clinical wound botulism in injecting drug addicts].

Wound botulism among drug abusers was first described in the USA in 1982. From 1988 to 1995, 46 laboratory confirmed cases were reported in California. The condition occurred for the first time in Norway in 1997 when three cases of suspected wound botulism among drug users who injected heroin subcutaneously or intramuscularly were reported. Two of these cases are presented here with neurophysiological findings and differential diagnosis.

Adult↗
PubMed1998

[Botulism after intake of half-fermented fish].

From 1975 to 1997, 21 cases of foodborn botulism have been reported in Norway. Half-fermented fish is the major cause. We describe one patient with botulism following intake of home-prepared half-fermented fish. Seven people had eaten fish from the same bucket, but only two developed symptoms. The fish was initially stored at 13 degrees C; this probably explains why toxin developed. Type E toxin in moderate concentrations was found in fish samples. The patient was treated with specific antitoxin and made a gradual recovery. He returned to work after eight months.

Adult↗
PubMed1998

[Yellow staphylococci with borderline resistance to methicillin].

Over the last four years there has been an increase in the incidence of borderlineresistant Staphylococcus aureus isolated from bacteriological samples at the Ullevål University Hospital, Department of Medical Microbiology. Several severe infections caused by these bacteria have been noticed in the Department of Infectious Diseases at Ullevål University Hospital. From December 1994 to April 1997, 24 patients suffering from this type of S. aureus infection were examined with regard to clinical and microbiological outcome. 15 of the patients had hospital-acquired infections, and all except one had acquired the infection in Norway. 13 of the patients had at least one predisposing factor, 50% had received antibiotics (mainly cefalosporins) beforehand. Three of the 24 patients died from the infection. We discuss etiology, identification of groups at risk and management of the infection.

Adolescent↗
PubMed1998

[Bilateral pulmonary infiltrations in patients admitted to an intensive care unit].

Diffuse pulmonary infiltrates are commonly found in hypoxic respiratory failure. We have reviewed 16 patients admitted to our medical intensive care unit over a period of 21 months, of whom seven died in hospital. Only patients requiring ventilatory support (CPAP or mechanical ventilation) for respiratory failure due to non-cardiogenic causes were included. All patients met the criteria for the diagnosis of ARDS. Three patients suffered from Wegener's granulomatosis, three from Pneumocystis carinii pneumonia, three from bacterial pneumonia, and two from pneumonia. Staphylococcal septicemia, SLE, sarcoidosis, cancer-associated hemolytic-uremic syndrome and ARDS of unknown etiology were each found in one patient. We discuss diagnosis and treatment of such patients on the basis of our experience.

Adult↗
PubMed1998

[Infectious endocarditis at Ullevål hospital 1988-94. Echocardiographic investigation].

During a seven-year period (1998-94) 68 patients with infectious endocarditis were diagnosed at a university hospital. Staphylococcus aureus was the most common etiological agent (38%), followed by Streptococcus viridans (21%). In seven patients the diagnosis infectious endocarditis was first made during autopsy, all seven of them had the clinical diagnosis septicaemia. Surgery was performed on 41% of the patients. Case fatality was 34%. Case fatality was significantly higher for S aureus endocarditis than for S viridans endocarditis, 48% vs. 7% (p = 0.01). The advantages of transthoracic and transoesophageal echocardiography in the diagnosis and follow up of patients with infectious endocarditis is emphasized. In spite of these new diagnostic tools a definitive clinical diagnosis of infectious endocarditis was not made for 23% of the patients.

Adolescent↗
PubMed1997

[Urosepsis].

Septicemia as a result of urinary infection is a serious condition, almost always caused by gram-negative bacteria. The bacterial toxins have a profound influence on haemostasis, microcirculation, and cardiac anf respiratory function. This article contains a brief review of aetiology, pathogenesis, pathophysiology, diagnostic work-up and treatment of this life-threatening condition. As soon as specimens from urine and blood are sent for bacteriological examination, intravenous antibiotics are given. It is essential that free drainage of urine from both kidneys is established by means of a bladder catheter, retrograde catheterization or percutaneous nephrostomy. The development of septic shock is a life-threatening condition which should be treated in an intensive care unit with continuous monitoring of vital parameters.

Humans↗
PubMed1997

[Serious streptococcal infections of the head and neck region].

This article describes the four cases of serious infections caused by Streptococcus pyogenes in the head and neck. Three patients presented with invasive infections of the soft tissues in the neck and one with epiglottitis. Two patients fulfilled the criteria for toxic streptococcal shock syndrome. The incidence of severe streptococcal disease is increasing in Norway, which emphasizes the importance of an aggressive attitude when diagnosing and treating atypical throat infections.

Adult↗
PubMed1995

[Infections in intensive care units. A challenge for the specialist of infectious diseases?].

There is an obvious need for teamwork between different specialists on the diagnosis and treatment of patients in an intensive care unit. The infectious disease specialist must contribute by establishing definite and quick diagnosis of infections and by employing an adequate and sensible antibiotic policy for successful treatment. The local microbiological flora should be kept at an acceptable level of resistance to antibiotics, and preventive measures should be chosen carefully. To achieve this goal, extensive knowledge on antibiotics and microbial epidemiology is essential.

Bacterial Infections↗
PubMed1995

[Induced sputum. Indication for examination in Pneumocystis carinii pneumonia?].

Induced sputum is a simple, rapid, and non-invasive technique for detection of Pneumocystis carinii in patients with Pneumocystis carinii pneumonia. In this study 31 patients were examined both with induced sputum and bronchoalveolar lavage. P. carinii was found in 24 patients. In 68% of the samples obtained by the induced sputum method the microorganism was found after Giemsa or methenamine silver staining. In 32% the diagnosis was established in the lavage fluid only. Induced sputum is indicated in moderate cases of P. carinii infection. Bronchoalveolar lavage has to be performed in suspected cases where staining of induced sputum is negative and when coinfection with other microbial agents is suspected.

Bronchoalveolar Lavage Fluid↗
PubMed1992

[Myocarditis and pericarditis in connection with Campylobacter jejuni infection].

We describe a case of myo/pericarditis related to infection with C. jejuni. The microbe was repeatedly isolated from faeces and the patient had specific IgA, IgM and IgG antibodies, detected in serum samples by means of a DIG-ELISA method. The condition is rare and the pathogenesis unclear. The case described may be the result of a primary infection or a reactive immune response.

Adult↗
PubMed1992

Ciprofloxacin versus a tobramycin/cefuroxime combination in the treatment of serious systemic infections: a prospective, randomized and controlled study of efficacy and safety.

Sequential intravenous and oral ciprofloxacin (CF) was compared with a combination of tobramycin and cefuroxime (T/C) in the treatment of serious systemic infections. Altogether 310 patients were randomized, 160 receiving CF and 150 T/C, the 2 groups being reasonably well balanced. 29 patients without infection were excluded from the analysis. Complete clinical resolution was obtained in 75% (107/143) patients receiving CF and in 78% (107/138) receiving T/C; the difference was not statistically significant. The rate of bacterial eradication in septicaemia was 72% (95% confidence interval (95% c.i.): 58-86%) for patients treated with CF and 87% (95% c.i.: 77-96%) when T/C was given, while the eradication rates in urinary tract infection were 72% (95% c.i.: 54-90%) and 45% (95% c.i.: 23-67%) for CF and T/C, respectively. Significant differences in bacteriological response for other diagnoses were not detected. Also for lower respiratory tract infections (LTRI) the clinical and bacteriological responses were quite similar, although relatively more failures occurred in CF treated patients with LRTI caused by pneumococci. The frequencies of adverse reactions were comparable, but the reactions were less serious following CF treatment. Our results indicate that CF may be used for empirical treatment of serious infections. However, if pneumococcal etiology is likely, alternative antibiotics should be used, and if necessary, coverage against anaerobic bacteria should be added.

Adult↗
PubMed1986

Effect of fibroblast interferon and recombinant gamma interferon on zymosan-induced nitroblue tetrazolium reduction in mouse peritoneal macrophages.

Mouse peritoneal macrophages (MPM) were cultivated with a fibroblast interferon (IFN) preparation or recombinant gamma-IFN (rIFN-alpha) for 1, 24 or 48 h. The zymosan-induced reduction of nitroblue tetrazolium (NBT) in these MPM was then measured. Fibroblast IFN enhanced the NBT reducing capacity of MPM when the incubation period was 1 h. When the incubation period was extended to 48 h, a suppressed NBT reduction by fibroblast IFN treated MPM was recorded. The influence of rIFN-alpha on MPM with regard to NBT reduction was minor. Only when the MPM were treated with a moderate dose of rIFN-alpha (10 U/ml) for 48 h was an enhanced NBT reduction recorded.

Animals↗
PubMed1984

Septicaemia in granulocytopenic patients caused by multiresistant diphtheroid rods. A study of two cases.

Two cases of septicaemia in granulocytopenic patients are reported. Both were caused by multiresistant aerobic (JK-group) diphtheroid rods. The bacterial isolates were resistant to all commonly used antibacterial agents but showed good sensitivity to vancomycin and rifampicin. These agents should be included in the routine sensitivity testing of such isolates and diphtheroids should always be reported by the routine laboratory for granulocytopenic patients.

Adult↗