Vesicobullous lesions in a child. Bullous pemphigoid (BP).
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Biomedical subjects
Publications and source records attributed to E Zombai.
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A 34-year-old women had a hen's egg-sized supernumerary mammary gland with no nipple or areola in the left anterior axillary line for the last 8 years. The main complaint about the axillary "lump" was that it was aesthetically displeasing, and it was excised. The importance of an axillary breast lies in the possibility that pathologic changes could develop in its substance and that clinically it could be confused with a lipoma. Early diagnosis and correct excision are usually recommended.
INTRODUCTION: Cutaneous calcinosis, without any disturbance of phosphocalcic metabolism, secondary to circumscribed previous skin lesions are quite common. Those secondary to viral skin lesions are rare and worth of publication. CASE REPORT: A 73-year old female patient disclosed progressive calcinosis in the scar of a cervico-thoracic herpes zoster which occurred 20 years ago. DISCUSSION: The occurrence of a secondary calcinosis in an old scar is common and non specific: the eliciting role of a previous herpes virus infection (VZV) may be discussed in the reported case and in few other cases reported in the literature (HSV, CMV)
A case of metastasizing basal cell carcinoma in a 57-year-old male is described. The primary tumor localised on the left lower leg metastasized to near skin and inguinal lymph nodes. The primary and metastatic skin tumors were excised and the defects covered by free skin grafts. Besides, the inguinal lymph nodes were block dissected and a part 10 cm long of the left calf bone was resected.
The authors describe the case of a 40-year old female patient. Since her childhood she realised of her urine the black discoloration of the underwear. For about a year, without subjective complaints, blue-black color of the skin involved the axillae and pinnae. For a year appeared the increased pain of thoracal and lumbal spine column and the limitation of motion of these parts. The examination of urine, histological and electron microscopical findings, the X-ray photograph of the spinal column confirmed the diagnosis of alkaptonuria or rather congenital ochronosis.
The authors describe a typical case of a rare disease, disseminated cicatricial pemphigoid. At the site of the subepidermal bulla excessive scarring in seen. Electron microscopic examination reveals elastic fibrin deposition and incipient vacuolation under the basement membrane. The indirect immunoperoxidase study shows increased numbers of positive Langerhans cells, which support their antigen-presenting role.
The association of malignant lymphoma (M. Hodgkin) and verrucosis plantaris of abnormal extent was found in a young woman patient whose death was due to an underlying disease. In connection with this case the authors discuss the immunopathogenesis of malignant lymphomas (among them that of M. Hodgkin), the biology of human papilloma viruses as well as the common etiological aspects of the above immune deficient condition and the associated virus infection.
We report on the typical case of a 71-year-old male patient suffering from herpetiform dermatitis. Histological investigation and immunofluorescence revealed the characteristic features of pemphigus. The symptom disappeared after therapy with corticoids.
A 49-year-old male patient is presented, who developed hyperpigmented macules on the face. An exact classification of the disorder was not possible on the basis of anamnestic data, histology and electron microscopy. An attempt was made to differentiate it from other known dyschromias of the face.
We report on a young man having suffered from infiltrated, scaly, hyperkeratotic, erythematous skin eruptions since his birth, varying in its course. Histologic examination revealed erythrokeratodermia. Therapy with Etretinate led to rapid regression; on keeping the maintenance dose for a year, we did not observe any recurrences. Light and electron microscopical investigations were carried out both before and 7 weeks after treatment.
The authors present a 86 years old male patient with gradually developing upper right arm swelling. There were several hyperaemic papules, vesicles and teleangiectases on his arm. The histology revealed a lymphangitis carcinomatosa. There were no signs of any tumor, but multiple isotope accumulations in the bones. Anaplastic thyroid gland carcinoma with multiple metastases were found at autopsy.
The differential diagnosis and classification of acrokeratoelastoidosis, a relatively rare disorder, may cause difficulties. The authors therefore report the case of a 25-year-old male patient with characteristic clinical and histological signs of the disorder.
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A 14-years-old girl suddenly developed typical dermal signs of ashy-dermatosis at the time of menarche. After one year, the signs began to fade and had disappeared completely two years later. The direct immunofluorescence and the ultrastructure resemble lichen planus. Endocrine factors may have played a part in the presented case, considering the sudden onset at the time of menarche.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.