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Biomedical subjects

E Zeitler

Publications and source records attributed to E Zeitler.

233 records · Page 13Linked to original sources

Immediate sealing of arterial puncture site following femoropopliteal angioplasty: a prospective randomized trial.

PURPOSE: A new hemostatic puncture closure device (HPCD) was evaluated following femoropopliteal angioplasty. Efficacy in hemostasis and complications were compared between manual compression and the new system. METHODS: One hundred patients undergoing percutaneous interventional procedures were randomly assigned to receive either manual compression or HPCD. The time to complete hemostasis (when a compression bandage was applied) was noted as well as complications such as hematoma or arterial stenosis at the puncture site. Follow-up was by clinical examination and color-coded duplex sonography (CCDS). RESULTS: With the HPCD, immediate hemostasis was achieved in 22 patients (44%). Discrete oozing without the necessity of external compression or further consequences was observed in 11 patients. Mean manual compression time was 25 (+/- 20) min including application of the pressure bandage. Eleven patients needed additional manual compression and technical failures were observed in 6 patients (12%). The compression time in these 17 cases was 27 (+/- 12) min. Subcutaneous hematomata with a diameter of more than 5 cm developed in 15 of 48 patients in the HPCD group and in 14 of 48 patients in the manual compression group. No surgical or percutaneous intervention was necessary. The complication rate was comparably low in the experimental and control groups. CONCLUSION: Compared with manual compression HPCD is faster and more accurate for sealing the arterial puncture defect following angioplasty. After an initial learning curve, it is easy to handle and time-saving as well as convenient for the patient. Furthermore, immediate and full anticoagulation is possible and arterial inflow is not compromised. A drawback is the necessity of an 8 Fr sheath. Nevertheless, the complication rate is comparably low for both methods.

Adult↗

Peripheral nerve stimulation by time-varying magnetic fields.

PURPOSE: A study was performed to assess the stimulation threshold for healthy adults using sinusoidally oscillating gradients. METHOD: One hundred thirteen healthy adults were examined in the study. ECG and physiological parameters were measured. All measurements were performed of both the head and the abdomen. The subjects were measured in the supine position with the region of interest positioned in the center of the gradient coils. The measurement was performed for three orthogonal, four oblique, and double oblique orientations. RESULTS: No volunteer reported painful, severe stimulation. The mean thresholds for peripheral stimulation in head and body measurement were similar: 85.5% of stimulation during examination of the head and 87.6% during measurements of the abdomen were reported when the y-gradient was used. CONCLUSION: The greatest frequency of reported stimulations occurs when the y-gradient is used. This was confirmed by the results and supports the hypothesis that orthogonal to the y-axis the body has its largest conductive loop, resulting in the strongest peripheral stimulation.

Adult↗

Primary and late results of percutaneous transluminal angioplasty (PTA) in iliac and femoro-popliteal obliterations.

The results of a prospective PTA study with single teflon and Grüntzig balloon catheters are reported. The pre- and long-term medication is made with aggregation inhibitors. The primary results, the complication rate and the three-year patency rate indicate the prognosis to be expected. Hence it follows that the most favourable results in stage II to IV are obtainable in single iliac artery stenoses, isolated and multiple femoral or popliteal artery stenoses and femoro-popliteal occlusions up to 10 cm in length. Even in stage III/IV when vascular surgery is not possible and general contraindications to surgery exist can a treatment attempt be meaningful for femoral occlusions of longer extent. A significant reduction of the leg amputation rate is noticeable in stage III/IV.

Angioplasty, Balloon↗

Transluminal catheter dilatation. Indications, technical aspects, results.

After 18 years of PTA experience, the results of a prospective study concerning the follow-up patency rate is demonstrated. The best results were seen in patients with claudication (1011) and treatment of iliac or superficial femoral artery stenoses and occlusions in the superficial femoral artery smaller than 12 cm. The 5 years patency rate in patients with claudication was 85 to 89%, and 65 to 72% in 491 patients with rest pain or gangrene. The primary and late results in patients with superficial femoral artery occlusion of more than 12 cm in length were not as good. In patients with claudication (82) the primary success rate was only 68%, but the follow-up patency rate was nearly as good as in the others. Patients with gangrene and occlusions of more than 12 cm showed only in 52% good primary success and only a patency rate of 30% out of all patients after 5 years. In 42% of this group PTA was a limb-saving procedure. Special details of technique and indications are discussed.

Adult↗

Digital transvenous angiography in follow-up examinations after carotid reconstruction: early results.

A total of 187 check-up examinations by DVSA were carried out after various types of carotid reconstructions. The results were inconclusive in only 2.7% of the cases. A good or very good postoperative result could be demonstrated in 77.5%. A slight stenosis was present in 16%, a significant stenosis in 2.7% and a complete occlusion of the internal carotid artery in 1.1%. Patch plasty alone showed the best results followed by endarterectomy and endarterectomy with patch plasty. Segmental carotid resections and dilatations led to the poorest results. Most of those cases, where a stenosis recurred, it was already present immediately after the operation and only rarely caused by progression of the basic disease or intimal proliferation. The complication rate of DVSA was low. It is concluded that DVSA is a low risk and reliable method which can routinely be used in the postoperative evaluation of patients with carotid reconstructions.

Acute Kidney Injury↗

Surgical treatment of renal artery occlusive disease: long term results.

68 patients were operated on for renal artery occlusive disease. After a mean follow-up of 61 months renovascular hypertension was cured or markedly improved in 79.2%. The results depended mostly on the duration of preexisting hypertension and on the histology of the renal artery lesion. Forty-four months after surgery, 37 reconstructions were examined by angiography. Mostly digital subtraction technique was used. Total occlusion rate was 24%. Patency rates of autogenous vein bypass grafts were similar to prosthetic grafts. It is concluded that prosthetic grafts like PTFE are a reasonable alternative in aortorenal bypass procedures.

Adolescent↗