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Biomedical subjects

E Zderkiewicz

Publications and source records attributed to E Zderkiewicz.

At least 19 recordsLinked to original sources

[Resumption of professional work after cerebral aneurysm surgery].

The influence of various factors upon the resumption of professional work was examined in the group of 87 patients, who had undergone an operation of single cerebral aneurysms. Professional activity was resumed by 59.9% members of the examined group. The age and the level of education or professional training were found to be the most influential factor. The location of aneurysms and sex of patients was found to have no influence. The fact that greater percent of those living in the country resumed their professional activities than those living in towns or cities can be explained by greater difficulty in to suffering was a quite frequent factor which can be overcome due to proper information given to the patients, thereby the greater number of patients can resume their professional career.

Adult↗

[Biological and clinical significance of acute phase proteins with particular emphasis on the role of C-reactive protein].

The acute phase response is a non-specific, early phenomenon, in which the concentration of a number of plasma proteins is increased following most forms of tissue injury, bacterial infection, inflammation, malignant neoplasia and surgical procedures. These plasma proteins are collectively termed acute-phase proteins. Their most important role is to restore the homeostasis of human organism. C-reactive protein (CRP) regarding his dynamic reaction, is one of the best non-specific biochemical indicators of most disorders. The multiple quantitative measurement of CRP is usefull in the diagnosis, differentiation, the assessment of treatment effectiveness and patient's prognosis, additionally to other clinical parameters.

Acute-Phase Proteins↗

[Management in cases of multiple cerebral aneurysms].

In the management of multiple intracranial aneurysms one has to face some problems, which do not occur in cases with single ones. The majority of neurosurgeons nowadays trend to operate on all detected aneurysms. Some controversy still exists concerning operating strategy--to operate all aneurysms simultaneously or in stages. Those who advocate the late way of treatment have to recognise which one of aneurysms was the cause of haemorrhage and must be operated first. This is one of the main factors influencing the results of treatment of multiple cerebral aneurysms.

Humans↗

[Theories of intracranial aneurysm etiology].

The main theories of the origin of intracranial aneurysms as the most common vascular malformations are presented. Three main theories maintain that they are either the congenital, acquire or both of those defects. The presence of aneurysms in the bifurcations of the arteries with the loss of the muscle layer and the coexistence with other vascular malformations of the arteries and their rareness in children give the evidence of the acquire origin. The present theories join this two positions and take into consideration also the hemodynamic and inflammation as well as degeneration, atheromatosis, toxic and traumatic factors.

Hemodynamics↗

[Angiographic evaluation of the effectiveness of surgical treatment of intracranial aneurysm].

On the basis of control angiographies after surgical treatment of 59 intracranial aneurysms full effectiveness of aneurysm elimination from the circulation was assessed and found to be fully effective in 93.2% of cases. In 3 cases the aneurysmal sac was partially visualized, and in 2 cases the metal clip was found to have slipped off from the aneurysm neck. One of these patients was reoperated successfully. The investigations demonstrated in 17 cases (29%) presence of postoperative vasospasm, in 8 cases internal hydrocephalus following past bleeding and in 2 cases accumulation of cerebrospinal fluid in the subdural space. On the basis of literature reports and own experiences the authors stress the necessity of possibly early control angiography which should be accepted as a routine method. In case of internal hydrocephalus demonstration insertion of a ventriculoatrial shunt is suggested.

Adolescent↗

[Cerebral aneurysm associated with meningioma in the area of small wing of the sphenoid bone].

A patient is described in whom removal of meningioma situated on the small wing of the sphenoid bone was followed by haemorrhage from an aneurysm of the middle cerebral artery. The aneurysm was recognized only after angiography was done after the operation for brain tumour. The problem of lack of visualization of aneurysms situated in the vicinity of brain tumours and diagnostic difficulties in cases of coexistence of these diseases are discussed.

Adult↗

[Chronic bilateral subdural hematoma].

The authors report 31 patients treated surgically for chronic bilateral subdural haematomas stressing the diagnostic difficulties in such cases and discussing the value of radiological investigations and surgical methods, especially multipoint trepanation.

Adult↗