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Biomedical subjects

E Yunis

Publications and source records attributed to E Yunis.

102 records · Page 6Linked to original sources
PubMed1971

Human lymphocyte antigen reactivity modified by neuraminidase.

Human lymphocytes treated with neuraminidase (from Vibrio cholera) are more susceptible to lysis with antiserums directed against HL-A antigens in the cytotoxicity test than are the corresponding cells incubated in buffer. Enzymetreated cells are also lysed by antibodies other than those directed against HL-A, but control cells are not. The extra sensitivity to antibody disappears after 2 to 6 days in tissue culture.

Antigen-Antibody Reactions↗
PubMed1969

Human leukocyte antigenic specificity HL-A3: frequency of occurrence.

Reactivity of antiserum against HL-A3, a human leukocyte and tissue antigenic specificity, depends upon a property of the lymphocyte as well as on the potency of the serum. Many reactions of HL-A3 antiserums can only be recognized through absorption or by a two-stage test not in general use. Interpretations of donor-recipient compatibility and of the constitution of HL-A alleles affected by these findings.

Alleles↗
PubMedDate not supplied

XX males: two new cases.

Two new cases of phenotypic males with 46,XX karyotype are presented. Fluorescence, autoradiographic and centromeric heterochromatin studies in several lines, including testicular cells, failed to demonstrate the existence of the Y chromosome or the existence of distal Yq material translocated to another chromosome in the two patients. The Xg study in one of the patients and his family provided direct evidence of transmission of an X chromosome from father to son. We present indirect evidence favoring the mutation theory to explain the XX male phenotype.

Adult↗
PubMedDate not supplied

Does zonal aganglionosis really exist? Report of a rare variety of Hirschsprung's disease and review of the literature.

The aganglionic segment of intestine in Hirschsprung's disease begins at the anus and extends proximally for a distance that varies from case to case. Occasional reports describe patients in whom the aganglionosis is segmental, with normal distal innervation or a skip area of normal innervation within an area of aganglionosis. This paper describes 4 patients with Hirschsprung's disease wherein a segment of normally innervated colon was found in an otherwise aganglionic colon. Two of these patients were siblings with different fathers. Problems encountered in the management of these patients are detailed. In a critical review of the literature, 2 additional male patients with well-documented zonal aganglionosis were identified. Although variations from the usual morphology or Hirschsprung's disease do exist, they are so rare that they merit clinical consideration only when the anatomic record and the clinical course are in obvious disagreement. Rectal biopsy remains the best method for the diagnosis of Hirschsprung's disease.

Biopsy↗