[Significance of longitudinal kidney measurement in recurrent nonobstructive urinary tract infections in childhood].
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Biomedical subjects
Publications and source records attributed to E Willich.
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Radiological findings of segmental renal hypoplasia are reported, based on the observation of 6 children aged between 8 and 14. The leading clinical symptom is arterial hypertension. Urinary tract infection and proteinuria are additional common findings. Cases with bilateral disease often have renal failure. The intravenous urogram shows unilateral or bilateral small kidneys with segmental renal scarring and transverse lobulation. In the pathological areas the calyces are ectatic or clubbed and their infundibulum is elongated. Vesico-ureteral reflux is frequent. In angiography the lobulated segments appear hypovascular. Diagnosis was verified by histological examination.
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Six cases of accessory diaphragm, associated with respiratory symptoms are reported and of them two have so far been proved, by operation and autopsy, respectively. The described 15 cases in the medical literature are reviewed. The accessory diaphragm consists of a fibromuscular membrane separating the affected hemithorax into two cavities and in three cases a nerve supply has been reported. The diagnosis can be made by simple frontal and lateral roentgenograms of the chest. Typically they show a small lung with shift of the mediastinum to the affected side, an area of increased hazy density, lack of sharpness of the mediastinal structures and the cardiac border on the affected side and a characteristic strip of increased density paralleling the sternum in the lateral view. Roentgenologic differential diagnosis includes lobar atelectasis and pulmonary hypoplasia. There is a high incidence of associated pulmonary maldevelopment of the ipsilateral side and of vascular and cardiac malformations. Improper timing in the interaction of lung buds and septum transversum with the development of a double diaphragm possibly is responsible for this rare congenital anomaly. Usually it is encountered on the right side. Since pulmonary maldevelopment maintains repeated or chronic respiratory infections, recognition and operative therapy are essential.
Suprapubic bladder puncture has recently found additional employment in paediatric radiology as a technique for micturition cystourethrography. Experience of 247 micturition cystourethrographies (MCU) by means of suprapubic bladder puncture (SBP) in 210 children aged from 6 days to 15 years is reported. The technique is simple: complications were observed in 6%, but were harmless in nature. The advantages consist in the absolutely sterile procedure, less strain on the children, and the possibility of simultaneously obtaining bladder urine, directly, for bacteriological and cytological examination.
Clinical, biochemical, roentgenological, and histological features of slipped epiphyses (epiphysiolysis) in 11 out of 112 children with renal osteodystrophy have been analysed. Characteristic age-related patterns of involvement of different epiphyses are described. Quantitative measurements of iliac bone histology, serum parathyroid hormone levels, and clinical history show the presence of more advanced osteitis fibrosa in children with epiphysiolysis than in those without. A good correlation was found between serum parathormone levels and osteoclastic resorption, endosteal fibrosis as well as osteoid. Histological studies show that the radiolucent zone between the epiphyseal ossification centre and the metaphysis in x-rays is not caused by accumulation of cartilage and chondro-osteoid (as usually found in vitamin D deficiency rickets) but by the accumulation of woven bone and/or fibrous tissue. The response to vitamin D therapy in most cases was good. Parathyroidectomy was required in only one case.
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This reports about 54 children suffering from retroperitoneal tumors excluding renal tumors. Characteristic radiological findings of neuroblastomas, pheochromocytomas, suprarenal carcinomas, adenomas, and teratomas are discussed. The diagnosis is made by the following roentgenological investigations: intravenous urography via the V. cava as "Cavo-Urography" or infusion urography (including zonography), sonography and nuclear medicine studies. Arteriography, pneumoretroperitoneum and lymphography are indicated if the primary tumor is unknown, in order to reveal suspected metastases, to decide about operability and for controlling radiotherapy. Further radiological examinations are made depending on the type of the metastasis.
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