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Biomedical subjects

E Williams

Publications and source records attributed to E Williams.

At least 289 records · Page 16Linked to original sources

Biosystematics and diversity amongst novel carboxydotrophic actinomycetes.

Fifty-four carboxydotrophic actinomycetes isolated from soils and composts were compared through 119 unit characters with representative mesophilic and thermophilic streptomycetes. The data were examined using the Jaccard, pattern and simple matching coefficients and clustering achieved using the unweighted pair group method with arithmetic averages algorithm. Acceptable cophenetic correlation and test error values allowed confidence to be placed in the resultant numerical taxonomies. The carboxydotrophic actinomycetes, which were distinct from cluster-groups corresponding to the mesophilic and thermophilic streptomycetes, formed two major cluster-groups the members of which were examined for the presence of diagnostic chemical markers. All but two of the carboxydotrophic actinomycetes had a profile of chemical properties consistent with their assignment to the genus Streptomyces. Quantitative fatty acid data were examined using the SIMCA package and the two statistically significant groups obtained corresponded with the cluster-groups circumscribed in the numerical phenetic analysis. Members of the two groups were also distinguished on the basis of their phospholipid composition. The two strains that contained meso-as opposed to LL-diaminopimelic acid in their peptidoglycan also showed a distinct chemotaxonomic profile. It was concluded that the carboxydotrophic actinomycetes form a novel and taxonomically diverse group.

Actinomycetales↗

Retrospective analysis of Silastic implant arthroplasty of the first metatarsophalangeal joint.

The purpose of this study was to evaluate the outcome of implant arthroplasty according to subjective, biomechanic, and radiographic parameters over a long period of time. Implants in 40 feet (27 patients) were analyzed at an average follow-up time of 8.25 years and a mean patient age of 63. The results were consistent with the subjective findings of previous studies that demonstrated that most patients were satisfied with the procedure. Ninety-six percent of the patients in this study confirmed they would undergo the procedure a second time. The radiographic results did not demonstrate a high incidence of implant fracture as previously reported. This review suggests that implants can be effective when used with patients who are carefully selected according to age, activity level, and diagnosis.

Aged↗

Detection of Chlamydia trachomatis in first catch urine samples from symptomatic and asymptomatic males.

BACKGROUND AND OBJECTIVES: Non-invasive tests are needed to detect Chlamydia trachomatis in the genital tract. For men, urine appears to be a useful specimen for chlamydial antigen or nucleic acid detection. GOAL OF THIS STUDY: To evaluate enzyme immunoassays (EIA) for chlamydial antigens in first catch urine (FCU) from symptomatic and asymptomatic men. STUDY DESIGN: We conducted five different studies; FCUs and urethral swabs were collected from 1,341 symptomatic and 816 asymptomatic males. Four EIAs (SureCell, Chlamydiazyme, MicroTrak and IDEIA) were tested on the FCU sediments. RESULTS: Prevalence of chlamydia by tissue culture isolation was 6% for asymptomatic and 14% for symptomatic men. With symptomatic males, the EIA sensitivities and specificities were: SureCell 85% and 97%, IDEIA 82% and 98%, MicroTrak 86% and 99%, and Chlamydiazyme 91% and 95%. For asymptomatic men, Chlamydiazyme sensitivity was 35% with frozen urine vs 77% with fresh urine. Overall, tissue culture sensitivity was about 90%. CONCLUSION: EIA results on FCU sediments are comparable to that of tissue culture isolation on urethral swabs. In many settings, FCU may be the specimen of choice for diagnosing chlamydial infections in men.

Chlamydia Infections↗

The family with AIDS: multiple challenges for caregivers.

Acquired Immune Deficiency Syndrome (AIDS) continues to increase in the United States, especially among minority groups. The disease is impacting not only individuals, but entire families through multiple infections of family members. This results in simultaneous illness and multiple loss within the family system. Delivery and management of quality care for the family is often made difficult by the lack of resources experienced by families with limited income and the multiplicity of problems associated with poverty in the US. This presents numerous challenges to health care providers. Utilizing a case study, this article presents a model demonstrating the coordination of services among several providers as a means of meeting a variety of family needs and providing quality, cost-effective care.

Acquired Immunodeficiency Syndrome↗

Fare's fair?

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Hospitals↗

Co-dependency.

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Alcoholism↗