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E Weissman

Publications and source records attributed to E Weissman.

6 recordsLinked to original sources

The cost of access to mental health services in managed care.

Managed care has controlled the cost of specialty mental health services, but its impact on access to care is not well described. In a retrospective design, the study used empirical data to demonstrate a direct relationship between managed care plans' claims costs per member per month and the proportion of plan members who use specialty mental health services annually. Each increment of $1 per member per month in spending on claims was associated with a.9 percent increase in the proportion of enrollees receiving specialty mental health treatment. These data raise concerns that plans with low per-member per-month costs may unduly restrict access to specialty treatment.

Cost Control↗

Sigmoidoscopy.

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Colorectal Neoplasms↗

Characterization of cholecystokinin from the human brain.

Human forms of cholecystokinin have not previously been characterized chemically. In this study, we have extracted and purified the predominant molecular form of cholecystokinin present in human cerebral cortex. The peptide was characterized by amino acid analysis, automated peptide sequencing, and fast atom bombardment mass spectrometry. It appears to be identical to porcine cholecystokinin-octapeptide, with the sequence of Asp-Tyr(SO3)-Met-Gly-Trp-Met-Asp-Phe(NH2). This structural identity is consistent with the observations that the peptide in human brain and porcine cholecystokinin-octapeptide are recognized similarly by a battery of antisera to porcine cholecystokinin; that they coelute from several chromatographic systems, including gel filtration, ion exchange, and reversed-phase; and that they possess similar biological activities.

Brain Chemistry↗

Interstitial lung disease in primary biliary cirrhosis.

A 51-year-old woman with a 5-1/2 year history of primary biliary cirrhosis (PBC) developed interstitial lung disease (ILD). The initial pulmonary infiltrate consisted of unilateral nodules mimicking neoplastic disease and later progressed to involve both lungs with a diffuse interstitial process. Tissue obtained by open lung biopsy was compatible with lymphoid interstitial pneumonia. The pulmonary infiltrates cleared spontaneously but recurred on two more occasions with subsequent resolution. This pulmonary disease activity appeared unrelated to the chemical activity of the PBC, which progressed to a fatal termination. The association of ILD, especially of a recurrent nature, with PBC is rare.

Female↗