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Biomedical subjects

E Weiss

Publications and source records attributed to E Weiss.

At least 127 records · Page 7Linked to original sources
PubMed1990

[Serum fructosamine assay in the evaluation and follow-up of diabetics].

Fructosamine (FRA) levels were determined in diabetic and nondiabetic patients. A normal mean of 2.38 mmol/L +/- 0.21 (SD), and range of 2.0-2.8, was found in 156 nondiabetic subjects. A highly significant correlation was found between FRA and glycosylated hemoglobin, and between FRA and fasting glucose and 2-hour postprandial glucose in the 163 diabetics. The mean FRA in 60 diabetics receiving oral hypoglycemic agents was 3.05 +/- 0.34. It ranged from 3.28 +/- 0.65 in patients with NIDDM receiving insulin to 3.50 +/- 1.03 in those with IDDM. Over 60% of the latter were inadequately controlled, as assessed by FRA levels. FRA repeated during 4-12 months in 68 patients showed no improvement in 45%, despite determined attempts to control blood glucose. However, fasting blood glucose in diabetics with normal FRA was 134 +/- 51 mg/dl. Therefore, a consistently normal level of FRA does not indicate normoglycemia. The FRA assay is rapid, simple, economical and of significant aid in the control of diabetes.

Blood Glucose↗
PubMed1990

Atypical presentation of pulmonary embolism.

Today we have discussed an interesting patient with an atypical presentation of pulmonary embolism. We have outlined a suggested algorithm to aid in the diagnosis and management of this disease. References 8 through 24 in the reference section are suggested readings that offer further insight into the diagnosis and management of this entity.

Aged↗
PubMed1990

[Doppler ultrasound findings in umbilical cord abnormalities. An in vivo model for clarifying resistance relations of the fetoplacental circulation].

In cases with different umbilical cord anomalies the influence of foetoplacental resistance on the flow velocity wave forms is discussed. If there is no anastomosis between the two umbilical arteries, the end-diastolic flow velocities depend on the volume of the foetoplacental vessel tree, i.e. higher resistance indices (RI) are found in the arteria with the smaller placental area. If there is only one umbilical artery, the peripheral resistance is reduced to 50%, because the part of the placenta part belonging to this solitary umbilical artery is twofold compared to cases with two umbilical arteries. This leads to a higher perfusion pressure gradient with higher flow velocities and lower RI values, resulting in an underestimation of the foetoplacental resistance. In cases of thrombosis of chorionic membrane vessels or stem villi vessels, placental regions are excluded from the perfusion, followed by an increasing foetoplacental resistance in the same manner as it happens in slowly developing failures of villus maturation. This means that the presented cases of umbilical cord anomalies and function disorders of allantois vessels can be interpreted as an in-vivo model to show pressure and resistance parameters in foetoplacental circulation.

Adult↗
PubMed1990

[Acute and chronic reduction of diastolic blood flow velocity in fetal umbilical arteries: a Doppler ultrasound study].

The significance of increased placental resistance for the development of fetal distress was examined in 800 pregnant women by pulsed Doppler flow velocimetry of the umbilical arteries. Moderately elevated resistance with reduced diastolic flow velocities with forward flow throughout the diastole, leads to an increased frequency of cesarean section for fetal distress and to a more negative fetal outcome. Severely elevated resistance of the fetal placental circulation shows absent diastolic velocities or even a diastolic reverse flow in the umbilical arteries. In 90% of 25 pregnancies this flow pattern leads to a premature delivery by cesarean section for fetal distress or to intrauterine fetal death. Standardised conditions of the Doppler signal measurement are required, before an absence of diastolic flow velocities is diagnosed. Acute changes in the resistance of the fetoplacental circulation were measured in 6 fetuses showing variable decelerations of the fetal heart rate (FHR). In 3 fetuses the flow curves showed a rapid change from normal to absent and to reverse diastolic flow during a period of time of 20-25 sec, which can indicate an acute resistance and a mechanical occlusion of the umbilical cord. Nevertheless, we found in 2 fetuses variable decelerations without any changes in the flow pattern of the umbilical arteries except for a frequency effect. One fetus showed both types of flow changes. Since two completely different sorts of flow changes exist, we conclude, that umbilical cord compression is not always the cause of variable decelerations of the FHR.

Asphyxia Neonatorum↗
PubMed1990

[Rate of spontaneous abortion in relation to the time of fetal viability assessment].

For the first time, the rate of spontaneous abortion is reported in a multicenter study of three different gynecological centers. In 1987 und 1988, the average spontaneous abortion rate in 315 pregnancies was 3.3%, after foetal heart actions had been verified by ultrasonic examination between the 7th and 12th week of gestation. A statistical significance has been calculated between the spontaneous abortion rate of 6.3%, if foetal heart beats were seen between the 7th and 9th week, and the spontaneous abortion rate of 1.0% with an evidence of foetal life (p less than 0.01) between the 10th to 12th week of gestation. The rate of spontaneous abortion of women above 34 years of age (8.9%) is statistically different (p less than 0.01) to that of women under 35 (1.9%). In women older than 34, the spontaneous abortion rate before the 10th week of gestation is 22.2% in contrast to 3.2% of women younger than 35 (p less than 0.01). Considering the evidence of foetal heart actions between the 10th and 12th week, the spontaneous abortion rate of women above the age of 34 is 1.9%, compared to 0.8% of women younger than 35. The statistical higher spontaneous abortion rate of women above the age of 34 before the 10th week of gestation and the lack of statistical difference of the abortion rate in this defined age group for foetal life to be proven from the 10th week on, should be an argument in favour of the 10th week of gestation as the earliest date of prenatal diagnosis.(ABSTRACT TRUNCATED AT 250 WORDS)

Abortion, Spontaneous↗
PubMed1990

[Does vascularization of the fetal placenta modify end-diastolic blood flow velocity in umbilical arteries? A histometric contribution to the validation of Doppler ultrasound].

The foetal intravillous blood volume was approximately determined in 90 cases, using placental histiometry post partum. This was compared with the Doppler sonographic flow patterns in the umbilical arteries determined during the last week ante partum. A direct dependence was seen: The larger the peripheral vascular tree of the placenta fetalis, the lower the resistance against the blood flow in the umbilical artery, i.e. the higher the enddiastolic blood flow velocities and vice versa. There is a highly significant correlation between the foetal intravillous blood volume and the foetal risks of Caesarean section performed, because of intrauterine asphyxia, growth retardation or reduced foetal outcome.

Asphyxia Neonatorum↗
PubMed1990

[The genesis of permanent growth of the beak wattle of a wattle-type pigeon].

Variation in size of warts located on the beak of wattle-pigeons represents a dominant trait of this breed. Excessive growth to extraordinary size in two breeds (barbs and carriers), in addition to a large beak, can cause losses due to the inability of the parents to feed the offspring properly. In older birds, respiration is impeded and the field of vision is limited. This permanent growth in barbs and carriers could not be attributed neither to an infection with papovaviruses, nor to the overexpression of the retroviral c-src-protooncogen. This finding, in conjunction with the genetic analysis, underlines that this prominent trait is genetically determined.

Animals↗
PubMed1989

[Accidental thymus involution in calves].

In 149 necropsied calves (age 0 to 28 days) a reduced thymus was found. The absolute thymus weights varied between 6 and 220 g. The relative thymus weights (applied to bodyweight) were between 0.02 and 0.52% (healthy controls 0.24 to 0.67%). The histological changes resemble those of accidental thymus involution. Corresponding to the duration of the disease and/or loss of body weight of the animals there is an increase of lymphocyte depletion. The accidental thymus involution is presumed to be a morphological expression of a secondary immunodeficiency.

Animals↗
PubMed1989

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6.

Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the alpha-helical region of the alpha 1 domain flanked by the amino acid positions 74-83. Comparison of their amino acid sequences with those of other HLA-B-locus alleles established HLA-Bw6 to be distinguished by Ser at residue 77 and Asn at residue 80. In contrast, HLA-Bw4 is characterized by at least seven different patterns of amino acid exchanges at positions 77 and 80-83. Reactivity patterns of Bw4- or Bw6-specific monoclonal antibodies reveal two alloantigenic epitopes contributing to the HLA-Bw4 or -Bw6 specificity residing next to the region of highest diversity of the alpha 1 domain.

Amino Acid Sequence↗
PubMed1989

Hysterical stridor: a benign cause of upper airway obstruction.

We present the cases of three patients with stridor that resolved spontaneously. Paradoxical vocal cord motion was documented in one patient. Normal vocal cord motion was present in the other two patients, but stridor had resolved in both cases. Many different terms have been used to describe this entity in the literature. Emergency physicians must recognize the subtle signs of hysterical stridor. Once more serious etiologies are ruled out, sedation and reassurance instead of aggressive airway intervention are required for this benign condition.

Adolescent↗