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Biomedical subjects

E Weinberger

Publications and source records attributed to E Weinberger.

60 records · Page 4Linked to original sources
PubMedDate not supplied

Discoid menisci in children: MR features.

OBJECTIVE: To define the MR appearance of discoid meniscus in children. MATERIALS AND METHODS: In 22 children (15 girls and 7 boys; age range 5-17 years; median age 9 years) who were referred for evaluation of painful knees 27 discoid lateral menisci were identified. Meniscal shape and signal intensity and abnormalities of the surrounding structures were evaluated and compared with adult standards. Clinical (11 knees) or surgical (10 knees) follow-up was available on 16 patients (21 knees). RESULTS: The menisci were classified as slab type (no. 20) or wedge type (no. 7). Transverse diameter at the midbody was 22.4 mm (range 10.5-36.7 mm) for discoid lateral menisci and 6 mm (range 5.1-28.3 mm) for medial menisci. Of 27 menisci, 23 had a central band of diffusely increased signal. Extension of intrameniscal signal to the joint space was noted in 16 of 23 menisci. Of 9 patients with intrameniscal signal who underwent surgery, only 7 had tears. Associated popliteal cysts occurred in 3 knees. No medial meniscal injury was observed. CONCLUSION: The characteristic MRI appearance of symptomatic discoid meniscus in children is that of a diffusely thick meniscus with a slab configuration and diffusely increased intrameniscal signal that may or may not extend to the joint surface.

Child↗
PubMedDate not supplied

Three-dimensional fast spin echo T1-weighted imaging of the pediatric spine.

OBJECTIVE: We evaluated the feasibility of using a three-dimensional (3D) fast SE (FSE) pulse sequence to acquire T1-weighted (T1W) images of the pediatric spine. MATERIALS AND METHODS: The 3D FSE T1W images were acquired in nine pediatric patients undergoing spine MRI for different clinical indications. The 3D FSE images were compared with our standard 2D SE T1W images. RESULTS: Image contrast was comparable between the two sequences. The 3D FSE sequence produced contiguous thin sections that allowed multiplanar reformations not possible with the 2D SE sequence. CONCLUSION: 3D T1W spine imaging with conventional SE-like contrast is feasible with 3D FSE.

Cerebrospinal Fluid↗
PubMedDate not supplied

Quantitative comparison of conventional spin echo and fast spin echo during brain myelination.

PURPOSE: Fast SE (FSE) sequences have largely replaced conventional SE (CSE) T2-weighted sequences in the brain and have been generally accepted as qualitatively comparable. The purpose of the present study was to subject these sequences to a quantitative comparative analysis in the brain. METHOD: A quantitative analysis of relative signal intensities of white and gray matter was performed comparing CSE and FSE T2-weighted sequences in brains of 20 children at varying stages of myelination. RESULTS AND CONCLUSION: At all ages in individual patients, white matter had less signal intensity (SI) relative to gray matter on FSE than CSE, though the relative difference in SI was small. This resulted in white matter appearing slightly more myelinated on FSE than CSE. This difference is attributed to differences in magnetization transfer. In myelinated brain (white matter hypointense to gray matter), contrast-to-noise was greater with FSE, while in unmyelinated brain, contrast-to-noise was greater with CSE.

Brain↗
PubMedDate not supplied

An unusual case of cellulitis associated with a Molteno implant in a 1-year-old child.

The Molteno seton implant has recently been used in pediatric patients with advanced childhood glaucoma, who would otherwise have been treated with cyclodestructive surgery. We report a case of Molteno implant (first stage) associated with orbital cellulitis in a 1-year-old child. The presence of the implant was initially unrecognized until, in the course of evaluation for orbital cellulitis, computerized tomography of the orbit suggested a foreign body. We believe this is the first report of a complication associated with the first stage of this procedure.

Cellulitis↗
PubMedDate not supplied

MR imaging of phenylketonuria.

Cranial MR imaging was performed on nine patients (13-27 years old) with classical phenylketonuria in order to define the spectrum of abnormal findings and to determine if these could be related to clinical or biochemical findings. MR abnormalities consistent with demyelination were found in varying degrees in a distribution corresponding to previous histopathologic studies. Specifically, increased signal was seen on T2-weighted sequences, most marked in the periventricular deep cerebral white matter. These changes were more prominent posteriorly, especially about the optic radiations. Comparison with clinical history and MR findings in this small series revealed that patients with adequate dietary control of phenylalanine levels had less severe white matter abnormalities than did patients with poorly controlled phenylalanine intake.

Adolescent↗