Differential activity of allelic gamma-globulin genes in antibody-producing cells.
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Biomedical subjects
Publications and source records attributed to E Weiler.
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This study examined the effects of age on the types of errors produced when recalling names of faces. The types of errors included confusions (errors within the target set), intrusions (errors outside the target set), errors phonologically similar to the target, errors not phonologically similar to the target, and errors containing the same number of syllables as the target name. Participants included 49 elderly adults (57-85 years) and 48 undergraduate students (18-44 years). Age group had a significant effect on the number of name errors produced (n=681 for elderly and n=422 for undergraduates). Elderly participants produced more confusions than their younger counterparts; however, younger participants produced significantly more intrusions. The age groups also differed in their production of error names that were phonologically similar to the target name. The elderly participants produced more errors that were not phonologically similar to the target than the young adults. The results are discussed with regard to theories of name-face association and tip-of-the-tongue phenomena.
SJL mice (CH allogroup Igb) were immunized against immunoglobulins from strain BALB/c (allogroup Iga). We used either animals purchased directly from the Jackson Institute, or Jackson-derived mice which had been inbred further in our laboratory. In some mice from three independent immunization series we observed, contrary to expectation, the expression of molecules carrying allotypic determinants of Iga instead of the expected production of antibodies against these determinants. Various types of breeding experiments were carried out with parents being either "orthodox" SJL mice, or animals expressing the "wrong" allotype. Among the progeny, as analyzed so far, we again found animals which changed their allotype after antiallotypic immunization. The data do not appear to be compatible with a single-gene, dominant mendelian inheritance of allotypic determinants in this stock of mice.