Identifying practice patterns for therapy interventions following distal radius fractures (DRFs) is necessary to define the most frequently used examination and intervention techniques. The purpose of this study was to identify preferred practice patterns and physical and functional outcome measures used during DRF management. Two hundred forty-two therapists (PTs, OTs, and CHTs) were surveyed by questionnaire at an annual hand therapy meeting. A descriptive analysis of data was performed. Preferred practice patterns during the immobilization and the post-immobilization periods were identified. More than 75% of the surveyed therapists used upper extremity range-of-motion exercises and compressive wrap with retrograde massage during the immobilization phase. More than 90% of therapists included range-of-motion exercises and heat/cold modalities in the post-immobilization treatment plans. Physical impairment measures of outcome were used much more frequently than functional outcome questionnaires in assessing progress during treatment. This study advances the evidence-based practice of therapy by establishing a foundation for future research.

Evidence-Based Medicine↗

PubMedDate not supplied

Comparison of N-linked oligosaccharides of recombinant human tissue kallikrein produced by Chinese hamster ovary cells on microcarrier beads and in serum-free suspension culture.

Glycosylation heterogeneity in recombinant human tissue kallikrein (r-HuTK) produced by Chinese hamster ovary (CHO) cells from microcarrier culture and from a serum-free suspension cell recycle process has been compared. Significant differences in the degree of sialylation were observed in glycoform distribution and oligosaccharide heterogeneity. High-performance liquid chromatography with a pellicular anion-exchange column under low pH eluant conditions was used to characterize the number and types of N-linked complex type oligosaccharides present. The oligosaccharides were released by N-glycanase and, after reduction, were resolved into a number of peaks containing one, two, three, and four sialic acids with an additional subfractionation based on the nature of the antennary structure. The microcarrier process resulted in a reduced amount of sialylated oligosaccharide species as compared to the suspension cell process. Removal of sialic acid followed by chromatography of the asialooligosaccharides under high pH anion-exchange conditions indicated that the same antennary structures were present but in slightly different relative amounts. The oligosaccharide profiles are indicative of a highly complex array of microheterogeneity present, encompassing mono-, di-, tri-, and tetrasialylated complex type oligosaccharides.

Animals↗

PubMedDate not supplied

Continuing education in nursing in Jamaica, West Indies.

Explore the source record for details and available documents.

Certification↗

PubMedDate not supplied

Continence. A basis for change.

Explore the source record for details and available documents.

Adolescent↗

PubMedDate not supplied

Dead to the world.

Explore the source record for details and available documents.

Adult↗

PubMedDate not supplied

Fine needle aspiration and endoscopic brush cytology: comparison of direct smears and rinsings.

When cellular samples obtained by endoscopic brushings and by fine needle aspirations were prepared by the direct smear thechnique, 22% were unsatisfactory due to scantiness of the cellular sample, air drying of the cells or bloodiness of the specimens. To improve diagnostic accuracy, an additional specimen was prepared by rinsing the brush or needle in a balanced salt solution, from which cells were recovered by membrane filtration. The combination of direct smears and rinsings decreased our unsatisfactory rate to 2% and increased our diagnosis rate for malignant neoplasms by 24%.

Biopsy, Needle↗