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Biomedical subjects

E Voigt

Publications and source records attributed to E Voigt.

At least 37 records · Page 2Linked to original sources

[Influence of left atrial pressure on left ventricular function after extracorporeal circulation (author's transl)].

In 10 patients with coronary heart disease, in 9 with advanced mitral and in 11 with aortic valve disease left ventricular function curves were constructed by volume loading immediately after cardiopulmonary bypass. After aortocoronary bypass surgery an approximately linear correlation between both cardiac index and stroke volume index and left ventricular filling pressure was demonstrated. After aortic and mitral valve replacement increase in left ventricular filling pressure above 15 mm Hg failed to result in significant increase in CI and SVI. Apparently, volume loading has limited effects in regulating left ventricular function in advanced aortic and mitral valve disease.

Atrial Function↗

[Material changes of plastic syringes (author's transl)].

During storage of syringes changes can develop in the material possibly depending on surrounding conditions. This can lead to precipitation of oleic acid amide into the lumen of the syringe. This material floats in corpuscular form on the injection fluid.

Oleic Acids↗

Enlarged acid-base and blood gas calculations by electronical data computing in the blood gas laboratory.

A rapid anaysis of parameters of the acid-base equilibrium and blood gases during open heart surgery and emergency therapy is absolutely necessary. Computing of the several parameters of the acid-base status by slide rules or nomograms is time consuming and can be shortened by computer applications. The central blood gas laboratory consists of a blood gas analyzer for PO2, PCO2 and pH, an electronic desktop calculator, a four color X-Y-plotter and two data lines to the cardiac surgery unit and to the intensive care unit. The time needed for computing and feedback of the parameters could be decreased to one quarter. In addition to numerical data printout, a graphical representation of the several parameters is possible on a X-Y-plotter and includes the Rahn-Fenn-O2-CO2-Diagram with venous admixture, ventilation perfusion ratio, alveolar dead space ventilation and the standard and actual oxygen dissociation curve as well as the pH/HCO3- Acid-Base nomogram. Furthermore, a computer diagnosis of the actual disturbances can be plotted.

Acid-Base Equilibrium↗

[Necessity to control endexpiratory CO2-concentration during laparoscopic sterilisation under general anaesthesia with controlled ventilation (author's transl)].

During laparoscopy and intraabdominal insufflation of CO2 cardio-respiratory accidents following increased PaCO2 are possible. The continuous measurement of endexpiratory CO2-concentration by infrared absorption spectrometry is a simple method for controlling the level of ventilation. Respiratory acidosis under controlled artificial ventilation during laparoscopy can thus be avoided.

Acidosis, Respiratory↗

[A new CO2 analyzer for monitoring of artificial ventilation (author's transl)].

A new CO2-Analyzer for continuous measurement of CO2 content during artificial respiration is described. Based on infra red absorption, this device may be used for measuring the carbon dioxide content of expiration in anaesthesia and intensive care. Carbon dioxide infrared absorption is affected by nitrous oxide. This side effect can be compensated by a single switch, if the sample contans N2O.

Anesthesia↗

[Data processing in the blood gas laboratory (author's transl)].

A computer-assisted system for the calculation of derived blood-gas and acid-base parameters, consisting of an analysator (AVL 937) desk calculator (HP 9825A) and external printer (HP 5150A) is described. For the calculation of the derived parameters corrections were made for patient temperature, plasma protein, reduced haemoglobin and CO2-carbamino haemoglobin. The time needed for calculating and feed back was shortened.

Blood Gas Analysis↗

[The role of ventilatory disturbances in the late postoperative hypoxaemia after upper abdominal surgery. A contribution to the risk of upper abdominal surgery in patients with respiratory damage (author's transl)].

The purpose of our investigations was to evaluate the influence of disturbed inspiratory gas distribution on postoperative hypoxemia in patients with abnormal lung function undergoing upper abdominal surgery. The lung function analyzer Hewlett-Packard 47402 A was used (Volume-time and flow-volume curves of forced expiration, single and multiple breath nitrogen washout tests with indices of ventilatory gas distribution). It was demonstrated that postoperative hypoxaemia in the undamaged lung is almost exclusively the result of augmented true right to left shunt. In patients with abnormal lung function the cause of postoperative hypoxaemia is, for the most part, an increase of disturbances of ventilatory gas distribution. These changes in the postoperative period can be explained by a reduction of FRC, that follows from changing of position (sitting-lying) and from pain. In patients with borderline lung function this reduction of FRC postoperatively may limit surgical treatment. The management of pain is of great importance in these patients. Continuous epidural anaesthesia certainly produces the best results in this respect.

Abdomen↗

[Ventilation distribution disorders. Evaluation based on nitrogen elimination curves of the lung and on an inspiratory gas-distribution index derived from it].

An uneven distribution of the inspiratory gas volume to the alveolar volume leads to disturbances of the ventilation/perfusion ratio VA/Q with resulting arterial hypoxemia. These ventilatory disturbances can be verified by nitrogen-washout-curves and an inspiratory gas distribution index derived from those curves. Preoperative diagnostic and the control of respiratory diseases during intensive therapy are possible without technical difficulties.

Humans↗

[Artificial ventilation of prematures and new bornes with the bennett pr-2 (author's transl)].

Difficulties and complications during artificial ventilation of prematures and newbornes gave rise to investigate the pressure-flow-characteritics during artificial respiration with the flow-time-cycled respirator Bennett PR-2 in combination with thin tracheal tubes. The flow and corresponding pressures generated by the respirator under different conditions were investigated. It is suggested that a sufficient respiration is not possible with a low generator pressure and high tidal frequencies under pathological conditions as it is often practised.

Humans↗

[Closing volume and ventilatory distribution disturbances (author's transl)].

Ventilatory disturbances are induced by airway closure associated with an increase of the venous admixture from alveoli with a low ventilation-perfusion-ratio. Closing volume was measured by single breath nitrogen washout curves and correlated with ventilatory disturbances derived from multiple breath nitrogen washout curves and an inspiratory gas distribution index (IDI). There was present a close correlation between the closing volume in relation to the functional residual capacity and the IDI. With rising closing volume in relation to functional residual capacity a deterioration of the inspiratory gas distribution with increasing venous admixture was observed.

Adolescent↗

[Disturbances of ventilatory distribution as a cause of postoperative hypoxemia after cardio-thoracic surgery (author's transl)].

In a group of 21 patients with thoracotomy the lung function was investigated pre-and postoperatively with particular consideration to N2-clearance. From the N2-clearance an Inspiratory Gas Distribution Index (IDI) is derived. This Index allows in combination with blood gas analysis an interpretation of ventilatory disturbances in the lung.

Blood Gas Analysis↗

[Studies on reducing the crude protein content of feeds fed to chicks and young hens (laying stock)].

2 rearing trials were carried out on a total of 8550 hybrid chicks (White Leghorn) to investigate in which way food mixtures containing reduced levels of crude protein (supplemented or unsupplemented with amino acids) might influence the growth of chicks and young hens. Decreases from 21.5% to 16.5% in the crude protein content of chicken feed and from 15% to 13% in feeds feed to young hens (greater than 8 weeks of life) did not reduce the live weight of birds at the end of the rearing period to any appreciable extent. No clearly defined differences were found to exist between the different types of feed tested concerning the amount of food and energy consumed per unit of weight gain and the mortality rate among the birds; it was shown, however, that the demand for crude protein per unit of weight gain was clearly reduced in birds reared at the lower crude protein level. For young hens receiving the diet poorer in protein the date when the birds began laying was slightly delayed. Otherwise, no statistically significant differences were found to exist between the young birds fed varying levels of crude protein, concerning the age at 50% laying performance and other parameters that are characteristic of the entire laying period (laying performance, weight of individual eggs, food consumption, mortality, fertilization of hatching eggs, hatchability of eggs). It appears that the feeding of a reduced protein diet to chicks and young hens (laying stock) did not have any detrimental effect on the growth and later laying performance of the birds. Apart from the fact that the demand for protein feeds is considerably reduced during the rearing period the costs of feeding per bird can also be cut down.

Animal Feed↗

[Gas exchange and pulmonary mechanics under anaesthesia and artificial ventilation (author's transl)].

During general anaesthesia with controlled ventilation and normocapnia the A-a DO2 and pulmonary shunt were investigated in a group of 7 patients undergoing a parotidectomy or laryngectomy. In a second group of 21 patients the behaviour of the total, lung- and thorax compliance was investigated. Within the first 1 1/2 hours after induction of anesthesia the A-a DO2 and shunt increased. During the time the thorax compliance did not change, whereas the total and lung compliance decreased significantly. After 1 1/2 hours no further change occured.

Adolescent↗