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E V Rozova

Publications and source records attributed to E V Rozova.

At least 19 recordsLinked to original sources
PubMed1994

[The physiological role of the structural-functional changes in the air-blood barrier of the lungs in supplying the body with oxygen under the action of extreme factors].

Hypoxic states, under the effect of extreme factors, induced changes in the endothelium of the lung capillaries irrespective of the nature of the factors (exo- or endogenous) causing the hypoxic state. Significant changes of the mitochondrial apparatus of the lung air-blood barrier cells occurred in the hypoxic hypoxia. The data obtained suggest that the thickness of the ABB, under extreme conditions, cannot serve as a parameter of the morphofunctional state of the lung ABB. The compensatory-adaptive response of the cell structures seem to decrease the oxygen diffusion from the alveolar gas into the blood of the lung capillaries.

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PubMed1992

[The morphofunctional characteristics of the pulmonary air-blood barrier in rats breathing gas mixtures with a high content of hydrogen sulfide].

The influence of gas mixtures with high concentration of pure hydrogen sulphide and natural gas of the Astrakhan deposit (NGAD) upon the morphofunctional state of the aerohematic barrier (AHB) and the surfactant system of the lungs was studied in 80 albino Wistar rats of 180-250 g body weight. The influence of both hydrogen sulphide and NGAD results in the appearance of morphofunctional alterations in the AHB and surfactant system of the lungs. However, if the action of hydrogen sulphide in concentrations of 300-330 and 600-700 mg/m3 is followed not only by pathological manifestations but also by mobilization of certain compensatory-adaptational mechanisms such as reinforcement of pinocytosis, the action of NGAD with the similar concentration of hydrogen sulphide seems to be too toxic, surpassing the possibilities of compensation, and there occurs the development of purely pathological phenomenon--pulmonary edema.

Animals↗
PubMed1989

[The electron microscopic characteristics of stress lung].

The influence of long-term (6 hours) immobilization stress on morphofunctional state of lung air-blood barrier was studied in experiments of the rats. It was shown that stress provoked the marked ultrastructural changes in the lungs, which were as follows: lung tissue oedema, pronounced thickening of lung air-blood barrier and its separate layers, edema-hemorrhagic syndrome, alveolar epithelial injury, disturbance of lung surfactant systems. Such a pathological complex may be designated as a "stress lung".

Animals↗
PubMed1988

[Changes in the blood-air barrier of the lungs in hyperthermia].

The influence of hyperthermia on the ultrastructure of lung air-blood barrier (ABB) was studied in experiments on dogs. It was shown that in hyperthermia both mean arithmetic and mean harmonic thickness of ABB were increased. The lung capillary endothelial layer was the most thick ABB layer, in which severe micropinocytosis could be observed. Marked destructive changes were noted in lung alveolar epithelial ABB layer up to the appearance of cell content in alveolar space and denudation of the epithelial basal membrane.

Animals↗
PubMed1983

[Changes in the air-blood barrier of the lungs during the breathing of helium-oxygen gas mixtures].

The changes in the pulmonary air-blood barrier (ABB), occurring under the influence of helium-oxygen gaseous mixtures containing 11, 21 and 40% O2 in helium were studied in rats of two age groups (adult animals and 2-week-old cubs). The mean arithmetic and harmonic thickness of the ABB increased and its ultrastructure changed. It is suggested that helium exerts an indirect effect on the pulmonary ABB and that this effect does not depend on the O2 concentration in a gaseous mixture or on the animals' age. The electron microscopy data have demonstrated the endothelium of lung capillaries to be the most sensitive structural component as regards the action of helium-oxygen gaseous mixtures.

Animals↗
PubMedDate not supplied

[Effect of the antihypoxic agent ionol on the morphofunctional state of the air-blood barrier of the lungs in hypoxic anoxia].

It is shown that antihypoxic ionol has promoted normalization of the air-blood lung barrier ultrastructure, activation of the surfactant system under acute hypoxic hypoxia effect as well as compensatory redistribution of the thickness of separate barrier layers due to intensified synthesis of phospholipids which are the components of cytoplasmic membranes and pulmonary surfactant.

Animals↗