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Biomedical subjects

E V Gruz

Publications and source records attributed to E V Gruz.

8 recordsLinked to original sources

[Optimization of anthrax vaccination on the basis of rational classification of populated sites].

The improved epidemiological situation requires the proper revision of the tactics used in vaccinating the population against anthrax. The important task lies in the optimization of the immunoprophylaxis of the rural population in accordance with the epizootologic situation in a given locality. To ensure correct orientation in choosing the groups of population to be vaccinated a rational classification of inhabited localities is proposed: they are classified as anthrax-free and anthrax-affected, and the latter fall into manifest, conditionally manifest, nonmanifest and unclassified. The use of the cartographic method based on this classification is recommended. The proposed vaccination tactics will allow to reduce the number of persons covered by immunoprophylaxis by 70-75%, making this coverage more exact, and to improve the epidemiological effectiveness of vaccination.

Agricultural Workers' Diseases↗

[Immunological properties of the preparations of the anti-anthrax antigen].

The results of examination of immunological properties of the preparations of anthrax protective antigen on laboratory animals (guinea pigs) confirmed the efficacy of using the lactic-peptone medium for obtaining the anthrax protective antigen. Incubation for 18 hours at 37 degrees C of the strain-producer (STI-1) and a double immunization scheme with the antigen obtained proved to be the most rational conditions for inducing the immunological response in the vaccinated laboratory animals. Three fractions of the anthrax protective antigen obtained possessed weaker immunobiological properties than the whole preparation of this antigen.

Animals↗