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E V Giulling

Publications and source records attributed to E V Giulling.

At least 37 records · Page 2Linked to original sources

[Study of the thymus as a source of humoral factors stimulating antibody formation].

A fraction stimulating antibody formation in neonatal animals was obtained in separation of the calf thymus extract (1A) prepared by the method of Goldstein et al. on a column with Sephadex G-25 (fine). Testing of the activity of analogous fractions of the extracts of calf tonsils, spleen, lymph nodes and the liver led to a supposition that the thymus was the only source of specific humoral factor stimulating antibody formation, which could accumulate in the peripheral lymphoid formations. Low activity of tonsillar extracts failed to confirm the hypothesis on the role played by the tonsils as the central immunity organ similar to the bursa Fabricii.

Animals↗

[Restoration of antibody synthesis by means of thymus extract in neonatally thymectomized animals].

One of the fractions of the thymus extract of a calf obtained by the authors restored the synthesis of antibodies to sheep erythrocytes in neonatally thymectomized mice and rats. Fractions isolated anologously from the tonsils and the lymph nodes failed to influence the antibody genesis. The data obtained are in favor of the endocrine function of the thymus of significance in the establishment and regulation of the immunological reactivity.

Animals↗

[Relation of atherogenesis and T-immunodeficiency].

Experiments on rabbits have shown that state of T-immunodeficiency induced by persisting virus infection promotes atherogenesis. Correction of age immunodeficiency by transplantation of the autologous bone marrow taken in young age considerably retards the atherosclerosis development. Inhibition of atherogenesis is also achieved by introduction (to animals) of natural thymic vilosene preparation which compensates a decrease in the functional activity of the thymus gland occurring under conditions of experimental hyperlipidemia.

Animals↗