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Biomedical subjects

E Trell

Publications and source records attributed to E Trell.

At least 91 records · Page 5Linked to original sources
PubMed1981

Smoking habits and carboxyhaemoglobin. A cross-sectional study of an urban population of middle-aged men.

In this cross-sectional population study we report on the distribution of carboxyhaemoglobin concentrations in the morning, before smoking, in an urban population of 1037 men born in 1931. The median concentration was the same in non-smokers as in ex-smokers: 0.5%. It increased with increasing daily tobacco consumption. But when carboxyhaemoglobin concentrations are measured in reasonably well-standardised circumstances there are large variations between individuals, even in those who smoke equal amounts of tobacco a day. This makes it difficult to predict the concentration in the individual smoker when only his daily tobacco consumption is known. Measurements of carboxyhaemoglobin concentration should be a valuable complement to smoking history to identify the smoker at high risk of cardiovascular disease, to provide an extra argument to make the patient give up the habit, and to reinforce the efforts of those who try to do so.

Carboxyhemoglobin↗
PubMed1980

Alcohol consumption and premature death in middle-aged men.

All the men living in Malmö born in 1926-9 were invited for a screening examination which included an assessment of alcohol consumption and measurement of gamma-glutamyltransferase (GGT) activity. They were followed for up to four years (median 2) and their mortality assessed. Sixty-two deaths occurred, 41 (0.9%) among the 4571 men who attended the screening investigation and 21 (1.3%) among the 1609 who did not respond to the invitation. Evidence of alcohol abuse or an alcohol-related cause of death was present in 25 (61%) of the deaths among the attenders and 13 (62%) of those among the non-responders. GGT values at the screening investigation were significantly increased in 19 (46%) of those who died, but established risk factors, such as cholesterol and triglyceride concentrations and blood pressure, had little predictive value. Measurement of GGT provided an objective index of alcohol consumption, though the full clinical importance of a raised value needs further assessment. The finding that heavy alcohol consumption was the single most important factor associated with premature death in these middle-aged men has important implications for prevention.

Alcohol Drinking↗
PubMed1980

Interactive computer system for monitoring multiphasic health screening.

In an on-going population screening investigation at the Department of Preventive Medicine in Malmö, an interactive computer system has been developed for monitoring: (i) the electron and invitation of the health screening population; (ii) on-line registration and representation of demographic informations, test results and questionnaires; (iii) generation of the patient files and other listings; (iv) systems for diagnostic and statistical processing and representation. Ten thousand health screening investigations have now been monitored by the system, which is described in this report.

Computers↗
PubMed1980

Hypertension, levels of serum gamma glutamyl transpeptidase and degree of blood pressure control in middle-aged males.

Among the first screened 2439 males born in 1926 and 1927, aged 48-49 years at the time of screening and representing 76% of these age cohorts, uncontrolled or partly controlled hypertension was found in 7.5%. Of these individuals, 30% preferred to remain with their physicians, regardless of the degree of control they had achieved. Among those who were referred to the Hypertension Unit (5.2% of the screened population), elevated S-GT levels (greater than or equal to 1.10 mukat/l) were found in 38.3%, against 18.5% in the two cohorts. During 24 months of treatment and follow-up only two men among the entire group of hypertensives referred dropped out, both were heavy drinkers (greater than 80 g alcohol daily). The mean BP after treatment was significantly lower among men with normal than high S-GT values or in those who admitted to heavy drinking. Of the 99 males treated for more than two years, 82 (83%) were responders (supine DBP less than or equal to 95 mmHg). Of the non-responders, 70% were either heavy drinkers or had abnormal S-GT values. The possible role of alcohol in the pathogenesis of essential hypertension in middle-aged males is discussed.

Alcohol Drinking↗
PubMed1980

Serum gamma-glutamyl transferase and a somatic health score in middle-aged men.

In an ongoing population investigation of middle-aged men in Malmö, Sweden, several health screening variables showed strong but crude individual covariations with the level of the hepatic enzyme, serum gamma-glutamyl transferase (GGT). These variables were combined, according to an analysis of their normal distributions, into a score index which exhibited a much smoother correlation with low, normal, and elevated levels of GGT when tested in a random population subsample. It is concluded that this scoring system may find further utilisation as a general descriptive method of recording statistical covariations between health screening tests and sum them up.

Adult↗
PubMed1978

Serum inorganic phosphate and serum calcium in middle-aged men. II. Relation to glucose and insulin parameters in glucose tolerance tests.

Fasting serum inorganic phosphate and fasting serum calcium were measured in 752 49-year-old Malmö males, in whom an oral or i.v. glucose tolerance test, in 189 cases including plasma insulin measurements, was performed as part of an internal medical screening examination. The serum inorganic phosphate and calcium levels were analysed statistically in relation to various glucose and insulin response parameters. A significant, positive correlation of serum inorganic phosphate with the early insulin response in the i.v. glucose tolerance tests was found but not with any of the other glucose or insulin response parameters included in the study. Serum calcium showed no significant correlations. These findings are discussed in relation to the pertinent literature.

Age Factors↗
PubMed1977

Serum inorganic phosphate in middle-aged men. I. Inverse relation to body weight.

Serum inorganic phosphate was determined in 752 men born in 1926. An inverse correlation was found between serum inorganic phosphate levels and body weight. Other parameters of possible relevance to this finding, such as serum calcium, serum albumin, serum lambda-glutamyltransferase, and the occurrence of upper gastrointestinal disorders were analysed, and no correlations to the phosphate level were detected.

Age Factors↗