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Biomedical subjects

E Taub

Publications and source records attributed to E Taub.

97 records · Page 6Linked to original sources

Behavioral development after forelimb deafferentation on day of birth in monkeys with and without blinding.

Four infant monkeys underwent somatosensory deafferentation of both forelimbs within hours after birth. Ambulation, climbing, and reaching toward objects developed spontaneously in each case. Thumb-forefinger prehension could be trained by operant shaping methods. Two infants deafferented at birth and blinded by eyelid closure were retarded in motor development by only 1 to 2 weeks. Results indicate that topographic sensory feedback and autogenetic spinal reflexes are not necessary after birth for the development of most types of movement performed by the forelimb musculature in monkeys.

Animals↗

Prism adaptation: control of intermanual transfer by distribution of practice.

Correction of errors in localizing movements produced by laterally displacing vision by means of wedge prisms has been termed "prism adaptation." Intermanual transfer of prism adaptation from an exposed to an unexposed hand, with subject's head immobilized, has been reported not to occur. However, it was found that a standard learning variable, distribution of practice, controls the occurrence or nonoccurrence of transfer. When practice is massed, there is no transfer of adaptation; when it is spaced, the transfer is extensive. Spacing of practice also influences the amount of aftereffect displayed by the exposed hand.

Adaptation, Ocular↗

Summated cortical evoked response testing in the deafferented primate.

Dorsal rhizotomy from C(2) or C(3) to T(4) in the primate results in failure to elicit summated cortical responses from systematic stimulation of the appropriate peripheral nerves. Under these conditions there is thus no evidence of sensory input into the cerebral cortex. A nonclassical mechanism must therefore be operational to explain the extensive purposive movements observed in the deafferented animals.

Animals↗

Deafferentation in monkeys: effect on conditioned grasp response.

A preliminary technique was developed for conditioning grasp response in monkeys, for use in studying the effect of damage to the central nervous system on skilled movement. That subjects were able to learn this response with a deafferented hand, in the absence of vision, indicated that purposive movements of the distal musculature are less under the control of peripheral feedback than had been generally believed.

Animals↗