Aompound tumour of the adrenal medulla.
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Biomedical subjects
Publications and source records attributed to E Tapp.
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An unusual tumour of the urinary bladder is described. It consists of two distinct nodules each with a quite different histological appearance, one being mucus-secreting adenocarcinoma, the other transitional cell carcinoma. Where the nodules are in contact there is little intermingling of the two histological patterns and it is suggested that the findings are probably due to the collision of two separate neoplasms. Metaplastic changes are present in the bladder mucosa adjacent to the tumour. The significance of these changes in the pathogenesis of adanocarcinoma is discussed.
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Three patients were found at necropsy to have Zahn's ;infarcts' of the liver. In one of these cases the ;infarct' merely showed severe centrilobular congestion. In the other two cases there was centrilobular necrosis, and in one of these early fibrosis was seen. Portal vein occlusion was present in all three cases and this had followed splenectomy in two of them. There was no evidence of hepatic artery or vein occlusion. Circulatory failure is considered to have played a part in the pathogenesis of the lesions.
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