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Biomedical subjects

E Takeuchi

Publications and source records attributed to E Takeuchi.

At least 181 records · Page 10Linked to original sources
PubMed1986

Long term results of mitral commissurotomy.

This study aims to evaluate the different surgical procedures used in 358 patients undergoing mitral commissurotomy. 89 patients underwent closed mitral commissurotomy by finger fracture (CMCF) and 162 by transventricular dilator (CMCD). 107 patients underwent open mitral commissurotomy (OMC). The following conclusions can be made: Commissurotomy is one of the better palliative procedures for mitral stenosis (MS). It is logical to continue the use of CMCD for selected patients with MS. A careful follow-up study of patients with mitral commissurotomy is necessary, and reoperation should be carried out positively when indicated. It has been confirmed in the survey that 7 patients out of 358 succumbed to sudden death. It is one of the goals of future work to determine the causes of sudden death and to develop an effective method of prevention. It can be expected that a patient with MS who undergoes a flawless operation at the right time will survive and recover full strength.

Actuarial Analysis↗
PubMed1985

Problems of artificial pacemaker therapy.

Four hundred and sixty-seven cases with implantation of an artificial pacemaker were studied. The postoperative survival rate was 63% for 15 years. Seventy-two percent of type III patients of the sick sinus syndrome were free from postoperative thromboembolism and the lowest of the three types of the sick sinus syndrome. Comparing postoperative physical activity, cardiothoracic ratio and exercise tolerance time, physiological pacing was superior to ventricular pacing in hemodynamic effects and clinical symptoms. In a hundred cases of physiological pacing, complications and problems of physiological pacing were discussed. Atrial sensing failure and over-sensing were observed in seven and two cases respectively. A low amplitude of atrial potential and use of unipolar atrial leads were considered to be the main causes of these complications. Bipolar lead should be used as the atrial lead to avoid such complications, because the atrial potential by bipolar leads is not less than that by unipolar leads. Atrial sensing may be more sensitive without electromagnetic interference. The fixed A-V delay time whenever the atrium is sensed or paced, often results in a ventricular fusion beat and hemodynamic change on every beat, according to the interval of atrial and ventricular contractions. The A-V delay time should be changed in accordance with atrial sensing or pacing.

Cardiac Pacing, Artificial↗
PubMed1985

Studies on the delayed neurotoxicity of organophosphorus compounds--(III).

TOCP (Tri-orthocresyl phosphate), an organophosphorus compound, has been implicated in producing neuropathy in the male S. D. rats. Repeated subcutaneous doses of TOCP (600 mg/kg) for up to 6 weeks produced ataxia, most striking at 50 days after final injection, followed by gradual recovery. Ultrastructurally, the internal structure of affected nerve fibers was primarily composed of altered smooth endoplasmic reticulum, tubular membrane system, and mitochondria, although myelin sheath was found to be essentially normal. In the histopathological examination, axonal and myelin degeneration was disclosed in the gracile nucleus and in the gracile fasciculus of the cords as well as in the sciatic nerves. The localization and degree of these changes were considered to be "dying back", showing systemic neuropathy. In addition, muscular lesion showed small group atrophy, corresponding to Type I fiber atrophy.

Animals↗