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Biomedical subjects

E T Jones

Publications and source records attributed to E T Jones.

30 records · Page 2Linked to original sources
PubMed1981

Pitfalls in the use of computed tomography for musculoskeletal tumors in children.

We retrospectively reviewed the use of computed tomography scans for the preoperative evaluation of musculoskeletal neoplasms in nineteen children. Of twenty-five scans, there was accurate correlation with the surgical findings in thirteen patients (fourteen scans), while overestimation or underestimation of the extent of soft-tissue disease was evident in nine patients (eleven scans). We concluded that computed tomography is a useful adjunct to the more conventional means of preoperative assessment but that overdependence on this one method of evaluation should be avoided.

Adolescent↗
PubMed1975

The sequence of amino acid residues around the oxidation-reduction active disulfide in yeast glutathione reductase.

A 14-residue peptide containing the oxidation-reduction active cystine residue from yeast glutathione reductase has been isolated from proteolytic digests of the enzyme in which the free sulfhydryl groups had been reacted with N-ethylmaleimide. The sequence of this disulfide-containing peptide was found to be:(see article). The sequence was highly homologous with the active cystine regions in Escherichia coli and pig heart lipoamide dehydrogenase. The sequences of three of the postulated four thiol-containing regions of the enzyme are also presented, as well as evidence supporting the view that the enzyme is composed of two identical subunits.

Amino Acid Sequence↗
PubMedDate not supplied

Infantile dislocation of the elbow complicating obstetric palsy.

This is a report of three cases of complete dislocation of both the radius and ulna at the elbow in infants born with obstetric palsy. All three patients had painless elbow-flexion contractures. The pathologic anatomy included (a) medial and posterior displacement of the radius and ulna on the humerus, (b) laxity of the lateral capsule and collateral ligaments, (c) contracted medial capsule and collateral ligaments, (d) contracted biceps and triceps muscles, and (e) hypoplasia of the capitellum, trochlea, coronoid process, and olecranon fossa. Open reduction was attempted in all three of these patients and was successful in two.

Birth Injuries↗
PubMedDate not supplied

Spinal deformity in idiopathic juvenile osteoporosis.

Idiopathic juvenile osteoporosis is an unusual condition appearing in the prepubertal child who is otherwise normal. Characteristically, the condition is of variable severity and of limited duration and always affect the spine. One of the major complications of idiopathic juvenile osteoporosis has been residual kyphosis. The present paper reports two cases of this condition and reviews the literature. The results of treatment with a Milwaukee brace in one case have been particularly gratifying and would indicate that brace treatment should be considered when this condition is encountered.

Adolescent↗
PubMedDate not supplied

Tetracycline labeling as an aid to complete excision of partial physeal arrest: a rabbit model.

We determined whether ultraviolet (UV) visualization of tetracycline-labeled bone allows more complete excision of experimentally created physeal arrests while minimizing required bone resection. Lateral distal femoral growth arrests were surgically created bilaterally in eight 6-week-old New Zealand white rabbits, given 3 daily oxytetracycline doses (10 mg/kg); the animals were killed 6 weeks postoperatively. Femurs were excised and dissected free of soft tissue. Ten of 16 operated femurs randomized into two groups had consistent deformity. In group I, arrest was excised with a high-speed burr without, and, in group II, with ultraviolet visualization. In group II, metaphyseal bone and calcified arrest glowed brightly, contrasting well with the epiphyseal plate. All excised specimens were examined under x 9 magnification to assess remaining bone bridges. Excision defects were filled with modeling clay, which was then removed and weighed. Thorough excision was confirmed in each specimen. Resection was easier and less bone usually was resected in the UV group (difference not statistically significant). This technique would best be used in resection of arrests involving small physes such as the distal radius, in which maximal visualization and minimal resection are essential to preserve all possible growth potential. Tetracycline labeling and intraoperative UV visualization of fluorescence allows thorough excision of partial physeal arrest while minimizing required bone resection.

Animals↗
PubMedDate not supplied

Median nerve injuries associated with supracondylar fractures of the humerus in children.

If not specifically examined for median nerve function, partial injury associated with supracondylar fracture of the humerus in children will go unrecognized. These injuries occur in as high as 5% of supracondylar fractures of the humerus in children. The 6 patients reported here as well as many cases described in the orthopedic literature present evidence that special exercises and supportive care are important as soon as the fracture is healed. Functional return may be seen as long as 4 to 5 months following supracondylar fracture, and exploration should be delayed at least that long in this type of peripheral nerve injury.

Child↗
PubMedDate not supplied

Extremity lawn-mower injuries in children: report by the Research Committee of the Pediatric Orthopaedic Society of North America.

In a multicenter study of pediatric lawn-mower injuries (push or riding gas-powered machines), we reviewed 144 children at an average age of injury of 7.0 years; 77% were boys. Most injuries (92 of 104) occurred in the afternoon. The child was the machine operator in 36 cases, a bystander in 84, and a passenger in 21. The average hospital stay was 13.3 days with 2.6 surgeries per child. Amputations occurred in 67 children; 63 were unilateral and four bilateral; the most common level was the toes (63%). Blood transfusions were given to 35 children. Children injured by riding lawn mowers, when compared with those by push lawn mowers, were younger (5.4 vs. 11.0 years), less frequently the operator (15 vs. 60%), had longer hospitalizations (15.0 vs. 8.9 days), and required more surgeries (3.0 vs. 1.6) and blood transfusions (41 vs. 3%). Children with free flaps needed more transfusions (78 vs. 26%), and transfused children were younger (4.6 vs. 8.1 years), more likely to be bystanders (91 vs. 63%), required more surgeries (4.1 vs. 2.0), and were hospitalized longer (21.6 vs. 9.7 days). Soft-tissue infections occurred in eight of 118 and osteomyelitis occurred in six of 117 children. At an average follow-up of 1.9 years, there were 43 satisfactory and 84 unsatisfactory results. When excluding those children with amputations of digits, there were 42 satisfactory and 47 unsatisfactory results. If children younger than 14 years had not been permitted around lawn mowers, approximately 85% of the injuries in this report would have been prevented. Further public dissemination of the following information is needed: (a) children younger than 14 years should not operate lawn mowers, (b) children younger than 14 years should not be in the yard while the lawn is being mowed, and (c) no passengers, regardless of age, should be allowed on riding mowers.

Accidents, Home↗