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Biomedical subjects

E T Edens

Publications and source records attributed to E T Edens.

At least 19 recordsLinked to original sources
PubMed1986

Diagnostic application of a monoclonal antibody against small cell lung cancer.

A monoclonal antibody (MOC-1) directed against an antigen present in small cell lung cancer (SCLC) was used for diagnostic purposes. After screening of biopsy specimens of lung tumors, MOC-1 was found to react with SCLC (n = 10) and adenocarcinoma of the lung (4 of 9 cases). Except for a few cells in a poorly differentiated tumor, the reaction with squamous cell cancer was negative (n = 6). Staining with MOC-1 by an immunoperoxidase technique on imprints of biopsy specimens procured by rigid bronchoscopy was found to be a reliable and rapid method for diagnosing SCLC (16 of 17 positive). All cytologically proven bone marrow and pleural metastases of SCLC were found by staining on a cytospin preparation with MOC-1. Moreover, in three cytologically negative cases, MOC-1-positive cells were detected.

Antibodies, Monoclonal↗
PubMed1986

Experiences with the silicone T-tube in man and dog.

Silicone T-tubes are particularly useful for long-term stenting of the laryngotracheal airway. Silicone is useful when non-autogenous non-reactive soft material is wanted for use in the human and animal body. Two case reports illustrate the use of the silicone T-tube.

Adult↗
PubMed1985

Microendoscopic surgery of the hypopharyngeal pouch with the CO2 laser.

In 1964 we started to treat hypopharyngeal (Zenker's) diverticula endoscopically, using the procedure described by Dohlman. With the increase in the number of patients (350), the technique and the instruments used have improved. This paper describes the technique, which involves exposure of the tissue bridge between esophagus and diverticulum with the aid of a specially designed scope and subsequent severance with the CO2 laser of this bridge under microscopic control. The use of an operating microscope and the laser is a great improvement in endoscopic treatment of hypopharyngeal diverticula.

Diverticulum↗
PubMed1984

Leiomyo(sarco)ma of the oesophagus.

Leiomy(sarco)mas of the oesophagus are rare tumours, which often cause ill-defined disturbances in the passage of solid food. The diagnosis can be established by simple radiological examination and endoscopy. There is no infiltration of the mucosa and it is undesirable to take biopsy specimens from such tumours through intact mucosa. The treatment of choice of leiomyoma is enucleation; that of leiomyosarcoma is resection.

Adult↗
PubMed1981

Colon-interposition as replacement for the esophagus. A follow-up study.

The longterm results of the use of colon-interposition as a substitution for the esophagus have been studied. Colon-interposition was carried out in eleven patients. There was one operative death. A second child died of an unknown cause nine years and eight months after operation. Nine patients could be studied from sixteen years and nine months to thirteen months after the operation. In six patients a satisfactory result has been achieved. One child is staying in a psychiatric infirmary. Feeding problems due to recurrent fistulae have led to growth retardation in another patient, while a third patient has regurgitation symptoms. A study of the case histories gives insight into the many early and late complications which occur in this operative procedure. The colon-interposition is a complicated procedure and should only be carried out in centers for pediatric surgery, because of its specific indication, its technique and the occurrence of complications afterwards. The development of alternative, less complicated, methods leaves a restricted indication for colon-interposition.

Adolescent↗
PubMed1978

Intramural diverticulosis of the esophagus.

A description is given of the etiology and pathology of intramural esophageal diverticulosis as so far discussed in the literature. In view of the course and the clinical findings in two young patients in whom this diagnosis was established, it is suggested that intramural diverticulosis develops as a result of a devolopmental disorder in the autonomic nervous system.

Adolescent↗
PubMed1977

Viral lesions of the respiratory tract compared to iatrogenic trauma.

A comparison between the mucosal pathology of the respiratory tract in cases of viral infections and of iatrogenic trauma after bronchoscopy and tantalum bronchography indicates that the respiratory mucosa has a very high degree of resistance against infection after trauma and is capable of rapid regeneration as long as the production of mucus continues and the surface remains moist. Viral infection might primarily inhibit mucus production and open the road to secondary infection.

Animals↗