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Biomedical subjects

E Strandman

Publications and source records attributed to E Strandman.

33 records · Page 2Linked to original sources

"Psychogenic needs" in patients with affective disorders.

To investigate the occurrence of different psychogenic needs or groups of needs, 118 consecutive out-patients with previous depressive disorders were asked to complete the Cesarec and Marke Personality Inventory; 103 completed it. Strict diagnostic criteria were used in subgrouping the series which thus consisted of unipolar depressive psychosis (UP), 26 patients; bipolar depressive psychosis (BP), 16; unclassified depression (NUD), 8; and reactio neurotico-depressive (RND), 15. BP distinguished themselves from the other groups by a tendency to have a reduced need of approval, dependency, guilt feelings and ego conflicts and a stronger wish to dominate and lead. These results are in line with earlier findings. The NUD group was small but tended to have extreme scores, i.e. a particularly weak need to dominate and to be in the centre but also to be cared for.

Adjustment Disorders↗

Serum dopamine-beta-hydroxylase in affective disorders.

Serum dopamine-beta-hydroxylase (DBH) activity was tested in 160 psychiatric patients suffering from affective disorders. The patients were divided into subgroups according to strict diagnostic criteria and clinical state at the time of the examination. Since no relationship was found between DBH activity and age or sex, these variables have been discarded from further analyses. Bipolar (manic-depressive) patients had lower (p less than 0.05) BDH mean values than patients suffering from unipolar, recurrent depressive psychoses. No other differences were found either among group or in relation to the clinical state. As such a wide range of DBH values was recorded in all the groups examined, measurements of DBH activity do not seem to be useful as a diagnostic acid, or as an indicator of the clinical state of patients suffering from affective disorders.

Adult↗

Genetic markers in cycloid psychosis.

Frequencies of HLA antigens, blood groups, serum groups and red cell enzyme types in patients with cycloid psychosis were compared with those in patients with bipolar psychosis and in normal controls. Patients with cycloid psychosis showed (1) an increased frequency of the Rh-negative type compared to controls, (2) an increased frequency of the K(+) phenotype compared to both bipolar patients and controls, and (3) an increased frequency of the serum group Gc2--1.

Bipolar Disorder↗

Serum protein and red cell enzyme polymorphisms in affective disorders.

Frequencies of serum groups (Hp and Gc) and red cell enzyme types (PGM1, 6-PGD and ES D) were studied in 195 patients with affective disorders. The patients were classified into four groups: (1) bipolar (manic-depressive) psychosis; (2) unipolar, recurrent, depressive psychosis; (3) non-psychotic reactive depression, and (4) unclassifiable. The Hp2 gene was increased in reactive and unclassifiable patients, the PGM1 1 gene was increased in bipolar patients and the ES D1 gene in reactive patients. No associations were found between affective disorders and the Gc and 6-PGD systems.

Affective Symptoms↗

Blood groups and affective disorders.

Frequencies of ABO, Rh, MNSs, P, Kell, Lewis and Duffy blood groups were studied in a total of 219 patients with affective disorders. The patients were classified into four groups: (1) bipolar (manic-depressive) psychosis; (2) unipolar recurrent depressive psychosis; (3) nonpsychotic 'reactive' depression, and (4) 'unclassifiable'. The following statistically significant results were found: an increased frequency of the blood group factor B among psychotic (bipolar and unipolar) patients compared to nonpsychotic patients, a decreased frequency of the SS phenotype in the unclassifiable group and an increased frequency of the K(+) phenotype among the nonpsychotic patients. Previous results concerning differences between bipolar and unipolar patients with respect to the A and O blood types were not confirmed in this investigation.

Affective Symptoms↗

HLA antigens and affective disorders.

A total of 168 patients with different types of affective disorders were examined with respect to their HLA antigens. The frequency of the A10 antigen was found to be increased in the patients particularly in those with the unipolar type of disease. The frequency of the A1 antigen was decreased among unipolar patients. A decreased frequency of the B7 antigen was found in the total material of patients, and in particular in those with a bipolar type of disease. Our results were in disagreement with findings by other investigators. So far there is no conclusive evidence for association between any HLA antigen and affective disorders.

Affective Symptoms↗

A comparison between "Cronholm-Ottosson depression rating scale" and variables concerned with depressive symptomatology in "the comprehensive psychopathological rating scale--CPRS".

In a study concerning 40 patients with depressive disorders the Cronholm-Ottosson depression rating scale and items concerning symptomatology from the Comprehensive Psychopathological Rating Scale--CPRS were compared. The total scores scales showed a rather satisfactory correlation (rs - 0,77). When patients were divided into two groups with depressive syndromes of a psychotic and non-psychotic dimension respectively the total scores of the items from CPRS from CPRS differed significantly for the groups while the total scores for the Cronholm-Ottosson depression rating scale showed a less pronounced, statistically non-significant difference between the groups, probably reflecting a reduced validity for the latter scale.

Adult↗

Diurnal variations in intensity of symptoms in patients of different diagnostic groups.

Consecutive patients, regardless of diagnostic group, upon admission to the Department of Psychiatry, University of Umea, were asked to fill in a special form about diurnal variation in their symptomatology and sleep disturbances. Three trained psychiatrists separately reviewed the records and completed a second form comprising information about diagnosis and certain background factors. Among the background factors only age and ongoing antidepressive medication were found to be of importance. In the study no strong consistency in the symptom complex of early awakening, experience of symptomatology as worst in the morning, and a feeling of relief in the afternoon was found. However, the experience of symptomatology as a whole, anxiety and inhibition as being worst in the morning is significantly more common in patients with unipolar and bipolar affective disorders but is also common in all diagnostic subgroups and seems in no way to be specific for depressive disorders. Furthermore, the phenomenon of diurnal variation of symptomatology was not found to be of diagnostic help and should be employed very cautiously as a basis in pathogenic consideration.

Adult↗

Prophylactic lithium and personality variables. An international collaborative study.

61 patients - 28 suffering from bipolar, and 33 from unipolar psychotic affective disorders - completed two personality inventories, one before and one about 6 months after starting lithium treatment to prevent relapses. On the basis of empirical observations it had been assumed that personality characteristics would change more in bipolar than in unipolar patients and that these changes would concern mainly those personality characteristics which reflect sociability and impulsivity. The inventories used were the EPI and the MNT. The results were in agreement with the predictions. Moreover, a significant decrease in N-scores was found both in bipolar and unipolar patients. It is assumed that these changes reflect both the therapeutic effect of lithium and an effect upon the personality characteristics of patients who suffer from bipolar or unipolar affective disorders.

Adult↗

The influence of carbon content on the mechanical properties in a cast dental Co-Cr alloy.

By varying the amount of acetylen in acetylene-oxygen flames Co-Cr test pieces with a varying carbon content were produced. The hardness, yield point for 0.05 per cent, 0.1 per cent and 0.2 per cent tensile strength and elongation were determined for these test-pieces. The results showed that hardness, yield points and tensile strength increased with increased carbon content, whereas the elongation lessened. The clinical importance of the altered mechanical properties due to increased carbon content in the Co-Cr alloy under study was discussed.

Carbon↗

The influence of different heat treatments on a dental Co-Cr alloy.

The change in microstructure and hardness in a cast Co-Cr alloy (type A) with a carbon content of 0.45% was studied both when the alloy was aged at temperatures between 600 degree C and 1200 degrees C and when it was isothermically heat-treated at temperatures between 800 degrees C and 1000 degrees C after solubility treatment at 1200 degrees C. Furthermore, studies were undertaken on how aging at 800 degrees C, solubility treatment at 1200 degrees C and isothermal heat treatment at 800 degrees C after solubility treatment at 1200 degrees C affected the mechanical properties. The results showed that both aging and isothermal heat treatment could change both microstructure and hardness. The changes in the mechanical properties by heat-treatment, however, did not improve the usefulness of the alloy in dentistry, principally because the elongation was reduced. The change in microstructure explained the change in hardness and in mechanical properties. It was interesting to note that the properties of a Co-Cr alloy were not affected by heat-treatment at temperatures below 600 degrees C. This means that addition of gold alloys, which are soldered to a base of Co-Cr, can be both homogenised and/or hardened without affecting the properties of the Co-Cr alloy.

Carbon↗

An equipment for standardized casting of Co-Cr alloys in dentistry.

The temperature and the chemical character of an acetylene-oxygen flame change with change in the gasmixture. When heating a Co-Cr alloy with this flame both temperature and chemical character in the parts of the flame used may influence the temperature increase of the alloy. To study the influence of different acetylene-oxygen flames on the heating process of dental Co-Cr alloy, a gasmeasuring and casting equipment was constructed. This made it possible to cast in a standardized way.

Acetylene↗

On the characteristics of acetylene-oxygen flames used in dental casting.

In a specially designed casting and gas measuring equipment the melting process used in dentistry for Co-Cr alloys using the acetylene-oxygen flame as heating source were investigated. The influence of different gas mixtures in the flame and different crucible temperatures on: 1. The temperature increase in the alloy. 2. The melting time of the alloy. 3. The temperature in the alloy when all the metal has melted and forms the spherical shape--the Bull's eye stage. 4. The melting time when different amounts of alloy were used in the melt. 5. The temperature increase and melting time when flux are used. 6. Different distances between the torch and the alloy. were studied. The results showed that the melting process is mainly governed by the heating effect and the chemical character of the parts of the flame used and also on the initial temperature of the crucible.

Acetylene↗

Influence of different types of acetylene-oxygen flames on the carbon content of a dental Co-Cr alloy.

The influence of different acetylene-oxygen flames on the carbon content of a dental cobalt-chromium alloy, type A, was studied under standardised casting conditions. The alloy was cast, both immediately after the formation of the Bull's eye and after prolonging the melting time. Further, the effect of re-casting, varying the amount of alloy casted and using different sections of the same acetylene-oxygen flame when melting was studied. The results showed on the one hand that the chemical character of the section of flame used and not the gasmixture as such determined the carbon content of the casting, and on the other that the acetylene-oxygen flames can increase but not decrease the carbon content in the casting. Increase of the carbon content of a cobalt-chromium alloy causes a considerable change in its microstructure.

Acetylene↗