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Biomedical subjects

E Stoupel

Publications and source records attributed to E Stoupel.

At least 73 records · Page 4Linked to original sources
PubMed1982

[Indirect evaluation of effort angina. Automatic and traditional analysis of the ST segment, the amplitude of the R wave and thallium scintiscanning].

Forty-six patients presenting typical or non-typical angina pectoris were all submitted to analysis of effort angina, traditional or automatic, and to analysis of the amplitude of the R wave and to an effort myocardial scan using thallium 201 (taken as reference substance) during maximal muscle exercise. The following conclusions may be drawn from this study. 1) Autoanalysis of the ECG improves considerably the sensitivity without changing the specificity of the method (92 and 82 p. cent for 79 and 82 p. cent). Analysis of the variations in amplitude of the R wave gave no further information. It should be reserved for patients whose effort ECG was difficult to interpret: e.g. left or right bundle branch block, digitalis effect, very abnormal resting ECG, or average age female population.

Adult↗
PubMed1981

Efficacy of intravenous disopyramide in acute cardiac arrhythmias.

The efficacy of intravenous disopyramide was studied during 200 episodes of supraventricular and ventricular arrhythmias in 160 patients, mainly presenting with acute myocardial infarction or cardiac failure. Disopyramide 50 mg was administered in a few seconds and any remaining dose within 2 to 5 min. The overall success rate was 80.5%. Intravenous disopyramide was more effective in patients with ventricular arrhythmias (85%) than in those with supraventricular arrhythmias (76%). Dose dependent prolongation of the PR interval, QRS time and the QT interval occurred in 16.32 and 20% of the cases, respectively. The adverse effects were aggravation of the arrhythmias, decrease of blood pressure and anticholinergic activity.

Acute Disease↗
PubMed1981

Analysis of exercise-induced R-wave-amplitude changes in detection of coronary artery disease in patients with typical or atypical chest pain under digitalis treatment.

Specificity and sensitivity of exercise ECG were compared to exercise stress thallium 201 scanning and coronary arteriograms in 70 male patients with typical or atypical chest pain complaints, without previous myocardial infarction. 50 patients (group I) did not receive any treatment; 20 patients (group II) received digitalis as preventive treatment of atrial arrhythmias or for no particular reason. Only subjects with concordant results in radionuclide and angiography examinations were considered as coronary artery disease patients. Exercise stress tests were performed sitting on the bicycle ergometer using a progressive loading profile (30 W for 3 min), to the symptom-limited capacity (VO2SL). Positive exercise ECG were confirmed on ST decrease (1.5 mm) or on absence or increase in R-wave-amplitude modifications (V5). In the group I patients, ECG-ST-modification sensitivity, specificity, predictive value (+) and efficiency were, respectively, 92, 82, 86 and 88%. R-wave-variation sensitivity, specificity, predictive value (+) and efficiency were, respectively, 41, 74, 65 and 56%. In the group II patients, ST-depression sensitivity, specificity, predictive value (+) and efficiency were, respectively, 100, 33, 59 and 65%. R-wave-variation sensitivity, specificity, predictive value (+) and efficiency were, respectively, 50, 70, 63 and 60%. It was concluded that R-wave-amplitude variations induced lower false positive responses than ST-segment depression in patients under digitalis treatment. False negative responses were unfortunately 50% using the R-wave criterion. Exercise ECG was finally judged as a poor indicator of CAD in patients under digitalis treatment.

Adult↗
PubMed1980

[Adult respiratory distress syndrome and military tuberculosis (author's transl)].

A patient with miliary tuberculosis developed the adult respiratory distress syndrome. The diagnosis of tuberculosis was not made especially because of several negative bacteriological examinations and of initial radiological aspects. Patient died of respiratory failure complicated with disseminated intravascular coagulation. This straightens the hypothesis of a physiopathological relationship between the two syndromes. The necessity of anti-tuberculous therapy should be evocated in every situation of adult respiratory distress syndrome of unknown origin.

Adult↗
PubMed1979

Cardiac tamponade with renal failure due to hemangioma of the heart.

In a 18 year-old woman, an isolated benign hemangioma of the right atrium led to cardiac tamponade and acute renal failure. After 8 days of anuria, the tumor was excised and replaced by a pericardial patch. The persistence of severe renal shutdown necessitated further hemodialysis during 22 days postoperatively. The patient was discharged on the 45th day in good hemodynamic and renal condition. Thirteen cases of benign hemangioma of the heart have been reported in the literature: 12 were found at autopsy; only 4 were complicated by hemopericardium but none of these survived.

Acute Kidney Injury↗
PubMed1976

Permeability of artificial membranes to a pluridisperse solution of 125I-polyvinylpyrrolidone.

The validity of the transport equation for uncharged macromolecules across a porous membrane developed by Verniory et al. (1973, J. Gen. Physiol. 62:489) has been tested on several types of artificial membranes (Amicon PM-30, XM-50, and XM-100 Diaflo ultrafilters) using a pluridisperse solution of polyvinylpyrrolidone as filtrand. The influence of the filtration pressure on the shape of the sieving curve predicted by the theory has been verified. A mean pore radius and the width of the pore demonstrated that the method used previously to determine the effective filtration pressure in the glomerulus from sieving data is valid. The transport equation previously proposed by Renkin (1954, J. Gen. Physiol. 38:225) gives results that are less consistent than those obtained with the new transport equation.

Iodine Radioisotopes↗
PubMed1975

The role of membrane parameters and of filtration pressure in the determination of the shape of the polyvinylpyrrolidone sieving curve. An in vitro and in vivo study.

The theoretical equations describing the transport of a solute across a porous membrane predict that the shape of the sieving curve (ratio of solute concentrations in filtrate and filtrand versus molecular size) depends not only on the porosity of the membrane but also on the filtration pressure. This has been verified experimentally on an artificial membrane (Amicon XM-50). This model has been used to interpret the effects of angiotensin II on the shape of the glomerular 125I PVP sieving curve. The mean effective filtration pressure is increased by the intrarenal perfusion of angiotensin II.

Angiotensin II↗