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Biomedical subjects

E Stieger

Publications and source records attributed to E Stieger.

4 recordsLinked to original sources

Sulfolobicins, specific proteinaceous toxins produced by strains of the extremely thermophilic archaeal genus Sulfolobus.

Several novel strains of "Sulfolobus islandicus" produced proteinaceous toxins, termed sulfolobicins, which killed cells of other strains of the same species, as well as of Sulfolobus solfataricus P1 and Sulfolobus shibatae B12, but not of the producer strains and of Sulfolobus acidocaldarius DSM639. The sulfolobicin purified from the strain HEN2/2 had a molecular mass of about 20 kDa. It was found to be associated with the producer cells as well as with cell-derived S-layer-coated spherical membrane vesicles 90 to 180 nm in diameter and was not released from the cells in soluble form.

Culture Media↗

[The Pola-test in asthenopia (author's transl)].

Seventy-three patients with asthenopia and 43 control subjects were examined with the Pola-Test. The two populations showed a significantly different frequency of pathologic results on the four test patterns. The so-called "stereo test" seems to be the most important test pattern. Patients with a pathologic stereo pattern reported asthenopic symptoms significantly more frequently than the control subjects who were questioned for similar symptoms. However, since 30% of the asthenopic patients showed normal results on the four Pola-Test patterns, the indication for treatment can be based only on a combined evaluation of binocular tests and asthenopic symptoms. In asthenopia visual and conjunctival symptoms are more prominent than headache. At times they may be masked by psychogenic factors. In a double-blind study on 12 asthenopic patients symptoms improved significantly during treatment with prisms.

Adult↗