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E Stern

Publications and source records attributed to E Stern.

123 records · Page 7Linked to original sources
PubMedDate not supplied

Fiberoptic intubation in the emergency department: a case series.

A prospective descriptive study was conducted to evaluate the feasibility of using fiberoptic bronchoscopy to replace blind nasotracheal intubation. The study was performed from November 1989 to August 1991 at a university teaching tertiary care hospital. Intubations were performed by three senior emergency physicians with no prior clinical experience in emergency fiberoptic intubation. Training in fiberoptic intubation was carried out on anesthetized patients, intubation manikins, and cadavers. All patients coming to the emergency department who would have been intubated in the blind nasotracheal manner were eligible for fiberoptic intubation, except for apneic patients and those intubated by residents learning other techniques. An independent observer collected the data. Forty-two patients were entered into the study, 22 males and 20 females, with an average age of 64 years. The success rate was 72% (30/42), with one of the investigators performing most of the intubations (22, 52%). His success rate was 82%. The other two investigators' success rates were 64% and 56%. Most failures were ascribed to coping with secretions. In conclusion, intubation with the fiberoptic bronchoscope can be a useful alternative to blind nasotracheal intubation. Success with this technique is dependent on the airway being free of secretions and blood.

Aged↗
PubMedDate not supplied

Effect of immunonutrition on virulence strategies in bacteria.

A coevolutionary balance exists between bacteria within the mammalian gastrointestinal tract and the lining epithelia. Recent advances in the molecular detection of bacteria have demonstrated that under normal circumstances, the lining mucosal epithelium in the gastrointestinal tract is sterile. Under conditions of stress and dietary alteration however, the probability of bacteria adhering to and altering epithelial function is a reflection of the virulence tactics of the resident bacteria balanced against the innate mucosal defense system. This pathologic event may be caused in part by the adaptive response of intestinal bacteria to their changing environment and food supply. Accustomed to a warm climate and a constant and predictable food supply, bacteria exposed to luminal nutrient starvation and a catabolically stressed host may express virulence determinants that can harm the host. The causes and consequences of bacterial adherence to host intestinal epithelia during stress and dietary manipulation are discussed.

Bacteria↗
PubMedDate not supplied

A simple method of producing a monolayer of cervical cells for digital image processing.

A manual method of producing a monolayer of isolated and evenly distributed cervical epithelial cells has been developed for use in an automated digital image analysis system. The cervical scrape specimen is vortexed from the spatula into a solution of Mucosol. The suspension is filtered through a 10 micro nylon mesh to remove polys and debris and then syringed to disaggregate epithelial clumps. The cells are plated out on a Nuclepore filter. The filter is touched directly onto a glass microscopic slide to transfer cells, which are then fixed and stained in a routine manner. Cell counts reveal elimination of 92% polys, with only 2% loss of squamous cells.

Autoanalysis↗
PubMedDate not supplied

Endocervical columnar cell atypia coincident with cervical neoplasia characterized by digital image analysis.

In the course of classifying uterine cervical epithelial cells for digital image analysis, certain changes in endocervical cells were observed. These changes coincided with the process ongoing in the squamous or metaplasia epithelium. Specifically, in severe dysplasias or carcinomas in situ (CIS), the endocervical nuclei reflected some of the same cytologic changes observed in the dysplastic or CIS squamous cells and yet definitely retained their columnar shape and cytoplasmic quality. This paper deals with almost unexplored area of the endocervical columnar cell in the face of significant cervical neoplasia. Correlation is made between the cytologic criteria observed by the human eye with the light microscope and significant parameters measured by digital image analysis. These measurements suggest that endocervical columnar cells may participate in the dysplastic progression toward CIS.

Carcinoma in Situ↗